STC2 rabbit monoclonal antibody interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and Catalog Number: H00008614-K phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive Regulatory Status: For research use only (RUO) overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced Product Description: Rabbit monoclonal antibody bone and skeletal muscle growth, and organomegaly. raised against a human STC2 peptide using ARM Expression of this gene is induced by estrogen and Technology. altered in some breast cancers. [provided by RefSeq]
Immunogen: A synthetic peptide of human STC2 is used for rabbit immunization. Customer or Abnova will decide on the preferred peptide sequence.
Host: Rabbit
Reactivity: Human
Applications: ELISA, WB-Tr (See our web site product page for detailed applications information)
Protocols: See our web site at http://www.abnova.com/support/protocols.asp or product page for detailed protocols
Purification: Protein A
Isotype: IgG
Storage Buffer: In 1x PBS, pH 7.4
Storage Instruction: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Entrez GeneID: 8614
Gene Symbol: STC2
Gene Alias: STC-2, STCRP
Gene Summary: This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may
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