Adenoid Hypertrophy & Adenoidectomy
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OM-85) on Frequency of Upper Respiratory Tract Infections and Size of Adenoid Tissue in Preschool Children with Adenoid Hypertrophy
STUDY PROTOCOL Effect of Vaxoral® (OM-85) on frequency of upper respiratory tract infections and size of adenoid tissue in preschool children with adenoid hypertrophy Study Product(s) Vaxoral® (OM-85) Indication Recurrent RTIs, adenoid hypertrophy Sponsor Dr Sami Ulus Maternity and Children Research and Training Hospital, Department of Pediatric Allergy and Immunology, Ankara, TURKEY Anticipated Turkey Countries Introduction OM-85 significantly reduces RTIs in children. This effect was proved by many clinical studies and meta-analyses1. A Cochrane meta-analysis first published in 2006 and updated recently (Del- Rio-Navarro 2012) showed that immunostimulants (IS) could reduce acute RTIs (ARTIs) by almost 39% when compared to placebo. Among the different IS, OM-85 showed the most robust evidence with 4 trials of “A quality” according to the Cochrane grading criteria. Pooling six OM-85 studies, the Cochrane review reported a mean number of ARTIs reduction by -1.20 [95% CI: - 1.75, -0.66] and a percentage difference in ARTIs by -35.9% [95% CI: -49.46, -22.35] compared to placebo1. Adenoid hypertrophy (AH) is one of the most important respiratory disease in preschool children2. In normal conditions adenoid tissue enlarges up to 5 years and become smaller afterwards. But in some children who have recurrent URTIs, it keeps growing and this can be associated with complications2. AH may cause recurrent respiratory infections and each infection contributes to enlargement of adenoid tissue thus promoting a vicious cycle. Additionally enlarged adenoids are known to be reservoir for microbes and cause of recurrent or long lasting RTIs3. AH is associated with chronic cough, recurrent and chronic sinusitis, recurrent tonsillitis, recurrent otitis media with effusion, recurrent other respiratory problems such as, nasal obstruction and sleep disturbances, sleep apneas2-3. -
Fossa of Rosenmüller Rosenmüller
Quick Review: Fossa of pharyngeal recess or the fossa of Rosenmüller Rosenmüller. The nasopharynx is a fibromuscular sling suspended from the skull base. The human nasopharynx is mainly derived from the primitive pharynx. It represents the nasal portion of the pharynx behind the nasal cavity and above the free border of the soft palate. The nasopharynx communicates with the nasal cavities through posterior nasal apertures. The choanal orifices along with the posterior edge of the Saggital section of the postnasal space (L E Loh et al 1991) nasal septum form the anterior boundary of the nasopharynx. The The superior constrictor muscle does superior surface of the soft palate not reach the base of skull hence a constitutes its floor and lateral gap (sinus of Morgagni) is velopharyngeal isthum provides created. Fossa of Rosenmüller is a communication between nasopharynx herniation of the nasopharyngeal and oropharynx. The body of mucosa through this deficiency sphenoid, basiocciput and first and between skull base and superior most second cervical vertebrae combine to fibers of the superior constrictor form roof of the nasopharynx. muscle. Through this gap bridged only by the pharyngobasilar fascia, the The part of nasopharynx proximal to eustachian tube enters the the tubal orifice is innervated by the nasopharynx with its two muscles, one maxillary division of the trigeminal (V) on each side. Along the inferior border nerve, and that posterior to the tubal of the two muscles the Fossa of orifice by the glossopharyngeal (IX) Rosenmüller is separated from the nerve. parapharyngeal space by mucosa and pharyngobasilar fascia. Functional studies with contrast and cinefluorography reveal structural The borders of the Fossa of differences between the two Rosenmüller are: components. -
Clinical Study Microbiological Profile of Adenoid Hypertrophy Correlates to Clinical Diagnosis in Children
Hindawi Publishing Corporation BioMed Research International Volume 2013, Article ID 629607, 10 pages http://dx.doi.org/10.1155/2013/629607 Clinical Study Microbiological Profile of Adenoid Hypertrophy Correlates to Clinical Diagnosis in Children Anita Szalmás,1 Zoltán Papp,2 Péter Csomor,2 József Kónya,1 István Sziklai,2 Zoltán Szekanecz,3 and Tamás Karosi2 1 Department of Medical Microbiology, Medical and Health Science Center, University of Debrecen, Nagyerdei Krt. 98, Debrecen 4032, Hungary 2 Department of Otolaryngology and Head and Neck Surgery, Medical and Health Science Center, University of Debrecen, Nagyerdei Krt. 98, Debrecen 4032, Hungary 3 Department of Rheumatology, Medical and Health Science Center, University of Debrecen, Nagyerdei Krt. 98, Debrecen 4032, Hungary Correspondence should be addressed to Tamas´ Karosi; [email protected] Received 24 April 2013; Accepted 23 August 2013 Academic Editor: Ralph Mosges¨ Copyright © 2013 Anita Szalmas´ et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Objective. Adenoid hypertrophy is a common condition in childhood, which may be associated with recurring acute otitis media (RAOM), otitis media with effusion (OME), and obstructive sleeppnea a syndrome (OSAS). These different clinical characteristics have some clinical overlap; however, they might be explained by distinct immunologic and infectious profiles and result in various histopathologic findings of adenoid specimens. Methods. A total of 59 children with adenoid hypertrophy undergoing adenoidectomy were studied. Three series of identical adenoid specimens were processed to hematoxylin-eosin (H.E.) and Gram staining and to respiratory virus specific real-time PCR, respectively. -
Dentofacial Development in Children with Chronic Nasal Respiratory Obstruction -- a Cephalometric Study
Loyola University Chicago Loyola eCommons Master's Theses Theses and Dissertations 1989 Dentofacial Development in Children with Chronic Nasal Respiratory Obstruction -- a Cephalometric Study Tai-Yang Hsi Loyola University Chicago Follow this and additional works at: https://ecommons.luc.edu/luc_theses Part of the Dentistry Commons Recommended Citation Hsi, Tai-Yang, "Dentofacial Development in Children with Chronic Nasal Respiratory Obstruction -- a Cephalometric Study" (1989). Master's Theses. 3577. https://ecommons.luc.edu/luc_theses/3577 This Thesis is brought to you for free and open access by the Theses and Dissertations at Loyola eCommons. It has been accepted for inclusion in Master's Theses by an authorized administrator of Loyola eCommons. For more information, please contact [email protected]. This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License. Copyright © 1989 Tai-Yang Hsi DENTOFACIAL DEVELOPMENT IN CHILDREN WITH CHRONIC NASAL RESPIRATORY OBSTRUCTION -- A CEPHALOMETRIC STUDY by TAI-YANG HSI B.D.S. A Thesis Submitted to the Faculty of the Graduate School of Loyola University of Chicago in Partial Fulfillment of the Requirements for the Degree of Master of Science December 1989 ACKNOWLEDGEMENTS I would like to express my sincere gratitude and appreciation to the following people: To Dr. Lewis klapper, Chairman of Orthodontics, thesis director, for his support, guidance and instruction through this investigation. To Dr. Richard Port, assistance professor of Orthodontic department, for passing his original study to me and his instruction and assistance. To Dr. Michael Kiely, Professor of department of Anatomy, for his instruction and assistance. To Delia Vazquez, clinic coordinator of Orthodontic department, for her assistance to take all the head x-ray film of all the patients in this study. -
Foley Catheter Action in the Nasopharynx a Cadaveric Study
ORIGINAL ARTICLE Foley Catheter Action in the Nasopharynx A Cadaveric Study Wai Chung Lee, FRCS(ORL); Peter Ka Ming Ku, FRCSEd; Charles Andrew van Hasselt, FRCS Objectives: To determine the action of the Foley cath- eral side at appropriate inflation volumes in 17 (85%) of eter in the posterior nasal cavity in relation to balloon 20 nasal fossae. Complete sealing between volumes of 12 volume, and to deduce its implications in the treatment and 15 mL was achieved in 13 fossae (65%), between 11 of posterior epistaxis. and 15 mL in 10 nasal fossae (50%), and between 5 and 15 mL in 3 nasal fossae (15%). Failure to seal at any vol- Design: Human cadaveric study. ume occurred in 3 nasal fossae (15%). Bimodal seal (ie, complete seal at high [15 mL] and low volumes [4-7 mL], Materials: Twenty nasal fossae of 10 adult cadavers. but leakage in intermediate volumes) occurred in 3 na- sal fossae (15%). The balloon remained in the nasopha- Interventions: A Foley catheter (size 14) was inserted rynx under traction and did not slip past the choanal rim into the nasopharynx via each nostril. The catheter bal- to encroach on the middle and inferior turbinates until loon was inflated to its recommended maximum vol- the balloon volume was reduced to between 4 and 7 mL. ume with 15 mL of water. Firm traction was applied to The balloon slid out of the nose at a volume of 5 mL or the catheter. Colored liquid was instilled into the ipsi- less. The inflation volumes ranging from 8 to 12 mL were lateral aspect of the nasal cavity, and liquid leakage into statistically more effective in sealing the choana than lower the contralateral side was monitored using a nasoendo- volumes (4-7 mL) (P,.002, x2 test). -
Mediastinum and Subcutaneous Emphysema: a Rare Complication of a Common Procedure
Case Report Brunei Int Med J. 2017; 13 (1): 29-32 Post adenotonsillectomy pneumo- mediastinum and subcutaneous emphysema: A rare complication of a common procedure. Farah Wahida ABD MANAB1,2, Nor Shahida ABDUL MUTALLIB1, Hisham ABDUL RAH- MAN1, Hamidah MAMAT1 1Department of otorhinolaryngology-Head and Neck surgery, Hospital Sultan Abdul Halim, Kedah, Malaysia, 2Department of Otorhinolaryngology, Head and Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia ABSTRACT Cervicofacial and pneumomediastinum subcutaneous emphysema is a very rare complication of adenotonsillectomy procedure. Even though it is a self limiting complication and can be treated conservatively, it can alarming for the patient or patient’s family as well as leading to more seri- ous and fatal consequences occurring from tension pneumomediastinum. We report a case of incidental finding of pneumomediastinum in postadenotonsillectomy patient. He was managed conservatively and made an uneventful recovery. Keywords: tonsillectomy, subcutaneous emphysema, complication INTRODUCTION Case Report Adenotonsillectomy is a common surgical pro- A 12 year old boy was admitted to our Ear, cedure among paediatric age group. It is rela- Nose and Throat (ENT) ward for elective sur- tively a safe procedure with minimal compli- gery of adenotonsillectomy. The indication for cations. Common complications are intraoper- surgery was recurrent attacks of acute tonsil- ative or postoperative haemorrhage, infec- litis. He had underlying Allergic Rhinitis and tion, damaged to soft tissue and surrounding Bronchial Asthma. structure such as teeth, odynophagia and oropharyngeal edema.1 Cervicofacial and Patient was given general anaesthesia with pneumomediastinum subcutaneous emphyse- fentanyl, propofol and cisatracium during in- ma is a very rare complication. -
Anatomy, Histology, and Embryology
ANATOMY, HISTOLOGY, 1 AND EMBRYOLOGY An understanding of the anatomic divisions composed of the vomer. This bone extends from of the head and neck, as well as their associ- the region of the sphenoid sinus posteriorly and ated normal histologic features, is of consider- superiorly, to the anterior edge of the hard pal- able importance when approaching head and ate. Superior to the vomer, the septum is formed neck pathology. The large number of disease by the perpendicular plate of the ethmoid processes that involve the head and neck area bone. The most anterior portion of the septum is a reflection of the many specialized tissues is septal cartilage, which articulates with both that are present and at risk for specific diseases. the vomer and the ethmoidal plate. Many neoplasms show a sharp predilection for The supporting structure of the lateral border this specific anatomic location, almost never of the nasal cavity is complex. Portions of the occurring elsewhere. An understanding of the nasal, ethmoid, and sphenoid bones contrib- location of normal olfactory mucosa allows ute to its formation. The lateral nasal wall is visualization of the sites of olfactory neuro- distinguished from the smooth surface of the blastoma; the boundaries of the nasopharynx nasal septum by its “scroll-shaped” superior, and its distinction from the nasal cavity mark middle, and inferior turbinates. The small su- the interface of endodermally and ectodermally perior turbinate and larger middle turbinate are derived tissues, a critical watershed in neoplasm distribution. Angiofibromas and so-called lym- phoepitheliomas, for example, almost exclu- sively arise on the nasopharyngeal side of this line, whereas schneiderian papillomas, lobular capillary hemangiomas, and sinonasal intesti- nal-type adenocarcinomas almost entirely arise anterior to the line, in the nasal cavity. -
Tonsillitis and Enlarged Adenoids and More
Tonsils and Adenoids Insight into tonsillectomy and adenoidectomy What conditions affect the tonsils and adenoids? When should I see a doctor? Common symptoms of tonsillitis and enlarged adenoids and more... Tonsils and adenoids are the body’s first line of defense as part of the immune system. They “sample” bacteria and viruses that enter the body through the mouth or nose, but they sometimes become infected. At times, they become more of a liability than an asset and may even cause airway obstruction or repeated bacterial infections. Your ear, nose, and throat (ENT) specialist can suggest the best treatment options. What are tonsils and adenoids? Tonsils and adenoids are similar to the lymph nodes or “glands” found in the neck, groin, and armpits. Tonsils are the two round lumps in the back of the throat. Adenoids are high in the throat behind the nose and the roof of the mouth (soft palate) and are not visible through the mouth or nose without special instruments. What affects tonsils and adenoids? The two most common problems affecting the tonsils and adenoids are recurrent infections of the nose and throat, and significant enlargement that causes nasal obstruction and/or breathing, swallowing, and sleep problems. Abscesses around the tonsils, chronic tonsillitis, and infections of small pockets within the tonsils that produce foul-smelling white deposits can also affect the tonsils and adenoids, making them sore and swollen. Cancers of the tonsil, while uncommon, require early diagnosis and aggressive treatment. When should I see a doctor? You should see your doctor when you or your child experience the common symptoms of infected or enlarged tonsils or adenoids. -
Adenoid Tissue Rhinopharyngeal Obstruction Grading Based on fiberendoscopic findings: a Novel Approach to Therapeutic Management
International Journal of Pediatric Otorhinolaryngology (2003) 67, 1303—1309 Adenoid tissue rhinopharyngeal obstruction grading based on fiberendoscopic findings: a novel approach to therapeutic management Pasquale Cassano a,1, Matteo Gelardi b,2, Michele Cassano b,*, M.L. Fiorella b, R. Fiorella b a Department of Otorhinolaryngology, University of Foggia, Foggia, Italy b Department of Otorhinolaryngology, University of Bari, Bari, Italy Received 6March 2002 ; received in revised form 26July 2003; accepted 27 July 2003 KEYWORDS Summary Objective: A grading into four classes of hypertrophied adenoid rhinopha- Nasal obstruction; ryngeal obstructions in children on the basis of fiberendoscopic findings to outline an Adenoid hypertrophy; effective therapeutic program according to this classification. Methods: Ninety-eight Rhinopharyngeal children with chronic nasal obstruction and oral respiration were examined by anterior fiberendoscopy; rhinoscopy, and fiberendoscopy. During the investigation, the fiberendoscopic images of the choanal openings were divided into four segments from the upper choanal Adenoidectomy; border to the nasal floor. In view of clinical findings, 78 patients also underwent ac- Adenoid grading; tive anterior rhinomanometry. Results: In eight patients (8.2%), the fiberendoscopic Upper respiratory tract imaging revealed that the adenoid tissue occupied only the upper segment in the phlogosis rhinopharyngeal cavity (<25%). Therefore, choanal openings were free (first degree obstructions). In 20 patients (20.4%), the adenoid tissue was confined to the upper half (<50%) of the rhinopharyngeal cavity (second degree obstructions) and in 63 pa- tients (64.3%) the tissue extended over the rhinopharynx (<75%) with obstruction of choanal openings and partial closure of tube ostium (third degree obstructions). Only in seven cases (7.14%), the obstruction was almost total. -
Pediatric Adenoidectomy
5/14/16 Pediatric Adenoidectomy: Clinical Update Shraddha Mukerji, MD, FACS Pediatric Otolaryngology Assistant Professor Baylor College of Medicine, Texas Children’s Hospital 05/14/2016 Talk Is Focused on • Clinical symptoms of large adenoids • Indications for adenoidectomy: updated guidelines • Complications and contra-indications 1 5/14/16 Basic Anatomy Relationship to Paranasal Sinuses and Eustachian Tube Paranasal sinus 2 5/14/16 Clinical Symptoms of Large Adenoids/Adenoid Inflammation Recurrent Sinusis or chronic Nasal sinusis symptoms ETD, AOM or Nasal obstruc;on OME Hyponasal speech Middle ear Mouth breathing problems Adenoid facies Adenoid Facies Long pinched nose Nasal obstruction Palatal and alveolar Crowding of teeth problems Mouth breathing 3 5/14/16 When to Perform Adenoidectomy in Children? • Nasal obstruction • Sleep disordered breathing, obstructive sleep apnea • Recurrent otitis media, otitis media with effusion • Recurrent or chronic sinusitis Case Scenario • A 2-year-old male comes for evaluation of symptoms of SDB: snoring, mouth breathing, restless sleeper • PE: normal weight child, 1+ tonsils, no turbinate hypertrophy 4 5/14/16 Next Step… • Intranasal steroid spray • Adenoid evaluation • Sleep study Adenoid Evaluation 5 5/14/16 Adenoidectomy is commonly performed for nasal obstruction and sleep apnea with or without tonsillectomy Adenoidectomy for OME and Recurrent AOM 6 5/14/16 Otitis Media and Adenoid Removal: Updated Guidelines Previous guidelines Newer guidelines • Adenoidectomy was performed for • If the child is LESS THAN 4 a child with otitis media who was YEARS, adenoidectomy is not undergoing a SECOND set of recommended even if the child is tubes, irrespective of age and nasal having a second set of tubes, symptoms. -
Evolution of the Nasal Structure in the Lower Tetrapods
AM. ZOOLOCIST, 7:397-413 (1967). Evolution of the Nasal Structure in the Lower Tetrapods THOMAS S. PARSONS Department of Zoology, University of Toronto, Toronto, Ontario, Canada SYNOPSIS. The gross structure of the nasal cavities and the distribution of the various types of epithelium lining them are described briefly; each living order of amphibians and reptiles possesses a characteristic and distinctive pattern. In most groups there are two sensory areas, one lined by olfactory epithelium with nerve libers leading to the main olfactory bulb and the other by vomeronasal epithelium Downloaded from https://academic.oup.com/icb/article/7/3/397/244929 by guest on 04 October 2021 with fibers to the accessory bulb. All amniotes except turtles have the vomeronasal epithelium in a ventromedial outpocketing of the nose, the Jacobson's organ, and have one or more conchae projecting into the nasal cavity from the lateral wall. Although urodeles and turtles possess the simplest nasal structure, it is not possible to show that they are primitive or to define a basic pattern for either amphibians or reptiles; all the living orders are specialized and the nasal anatomy of extinct orders is unknown. Thus it is impossible, at present, to give a convincing picture of the course of nasal evolution in the lower tetrapods. Despite the rather optimistic title of this (1948, squamates), Stebbins (1948, squa- paper, I shall, unfortunately, be able to do mates), Bellairs and Boyd (1950, squa- iittle more than make a few guesses about mates), and Parsons (1959a, reptiles). Most the evolution of the nose. I can and will of the following descriptions are based on mention briefly the major features of the these works, although others, specifically nasal anatomy of the living orders of cited in various places, were also used. -
Echocardiographic Characteristics of Nigerian Children with Adenoidal
nal atio Me sl d n ic a in r e T Animasahun et al., Transl Med (Sunnyvale) 2016, 6:4 Translational Medicine DOI: 10.4172/2161-1025.1000189 ISSN: 2161-1025 Research Article Open Access Echocardiographic Characteristics of Nigerian Children with Adenoidal Hypertrophy: A Multicenter Study Barakat Adeola Animasahun*, Motunrayo O Adekunle, Henry Olusegun Gbelee and Olisamedua Fidelis Njokanma Department of Paediatrics Lagos State University Teaching Hospital Ikeja, Lagos, Nigeria *Corresponding author: Adeola Barakat Animasahun, Lagos State University College of Medicine, Lagos, Nigeria, Tel: +2348055341166; Fax: 2348037250264; E-mail: [email protected] Recieved date: October 27, 2016; Accepted date: November 07, 2016; Published date: November 14, 2016 Copyright: © 2016 Animasahun AB, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Abstract Background: Adenoidal hypertrophy is a common respiratory disease in childhood with a lethal complication of Cor-Pulmonale. There are few studies on the prevalence of adenoidal hypertrophy in children in Nigeria. The aim of the current study is to document the echocardiographic characteristics of Nigerian Children with adenoidal hypertrophy and compare the findings with those of other children in other parts of the world. Method: The study was prospective, involving subjects from three centers which were; a tertiary hospital, a private hospital and a major cardiology center. Children with clinical and radiological diagnosis of adenoidal hypertrophy had transthoracic echocardiography done by a cardiologist. Results: A total of 1,346 children had echocardiography done within the three years studied period in the centers.