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Catalog Number:ATP217 Anti NSUN2 polyclonal antibody

Product overview product name Anti NSUN2 polyclonal antibody catalog No. ATP217

Category Primary antibody

Host Rabbit

Species specificity Human,other species was not test

Tested applications WB:1:2000~1:8000,ICC:1:50~200,IHC:1:50~100

Clonality Polyclonal

Conjugation Unconjugated

Immunogen Recombinant protein of human NSUN2(His415-Arg767).

Alternative Names tRNA methyltransferase 4 homolog,hTrm4,tRNA cytosine C(5)-methyltransferase,

RNA cytosine C(5)-methyltransferase NSUN2,NOL1/NOP2/Sun domain family

member 2,TRM4,SAKI,mRNA cytosine C(5)-methyltransferase,Myc-induced SUN

domain-containing protein,Misu,Substrate of AIM1/Aurora kinase B,NSUN2

Uniprot ID Q08J23

Product performance

Form Liquid

Buffer PBS,pH7.4,containing 0.05% proclin300,50% glycerol.

Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles.Store at 4°C

for frequent use.Store at -20 to -80 °C for twelve months from the date of receipt.

Concentration 0.68mg/ml

Isotype IgG

MW 86kDa

Purity Antigen affinity purification

Dilution range

WB,ICC,IHC

Product experiment picture

Web:www.atagenix.com E-mail: [email protected] Tel: 027-87433958 ATAGENIX LABORATORIES

Catalog Number:ATP217 Anti NSUN2 polyclonal antibody

Reference

PMID: 23871666,PMID: 22995836,PMID: 22395603,PMID: 19596847,PMID: 17071714

Product background

NSUN2, also known as SAKI or Misu (Myc-induced SUN-domain-containing protein) , is a methyltransferase which catalyses

(cytosine-5-)-methylation of tRNA. NSUN2 is direct target gene of c-Myc and may act downstream of Myc to regulate epidermal cell growth and proliferation. NSUN2 is overexpressed in various cancer tissues and may be a valuable target for cancer therapy and a cancer diagnostic marker. Recently a splicing mutation in NSUN2 has been identified as the cause of a Dubowitz- like syndrome, an autosomal recessive disorder.

Web:www.atagenix.com E-mail: [email protected] Tel: 027-87433958