Otosclerosis
Total Page:16
File Type:pdf, Size:1020Kb
Load more
Recommended publications
-
Perforated Eardrum
Vinod K. Anand, MD, FACS Nose and Sinus Clinic Perforated Eardrum A perforated eardrum is a hole or rupture m the eardrum, a thin membrane which separated the ear canal and the middle ear. The medical term for eardrum is tympanic membrane. The middle ear is connected to the nose by the eustachian tube. A perforated eardrum is often accompanied by decreased hearing and occasional discharge. Paih is usually not persistent. Causes of Eardrum Perforation The causes of perforated eardrum are usually from trauma or infection. A perforated eardrum can occur: if the ear is struck squarely with an open hand with a skull fracture after a sudden explosion if an object (such as a bobby pin, Q-tip, or stick) is pushed too far into the ear canal. as a result of hot slag (from welding) or acid entering the ear canal Middle ear infections may cause pain, hearing loss and spontaneous rupture (tear) of the eardrum resulting in a perforation. In this circumstance, there may be infected or bloody drainage from the ear. In medical terms, this is called otitis media with perforation. On rare occasions a small hole may remain in the eardrum after a previously placed P.E. tube (pressure equalizing) either falls out or is removed by the physician. Most eardrum perforations heal spontaneously within weeks after rupture, although some may take up to several months. During the healing process the ear must be protected from water and trauma. Those eardrum perforations which do not heal on their own may require surgery. Effects on Hearing from Perforated Eardrum Usually, the larger the perforation, the greater the loss of hearing. -
Experimental Studies on the Function of the Stapedius Muscle Inman
EXPERIMENTAL STUDIES ON THE FUNCTION OF THE STAPEDIUS MUSCLE INMAN AKADEMISK AVHANDLING som med vederbörligt tillstånd av Medicinska fakulteten vid Umeå Universitet för vinnande av medicine doktorsgrad offentligen försvaras i Samhällsvetarhuset, sal D, lördagen den 25 maj 1974 kl. 9.15 f.m. av JOHN-ERIK ZAKRISSON med.lic. UMEÅ 1974 UMEÀ UNIVERSITY MEDICAL DISSERTATIONS No. 18 1974 From the Department of Otorhinolaryngology, University of Umeå, Umeå, Sweden and the Division of Physiological Acoustics, Department of Physiology II, Karolinska Institutet, Stockholm, Sweden EXPERIMENTAL STUDIES ON THE FUNCTION OF THE STAPEDIUS MUSCLE IN MAN BY JOHN-ERIK ZAKRISSON UMEÂ 1974 To Karin Eva and Gunilla The present thesis is based on the following papers which will be referred to in the text by the Roman numerals: I. Zakrisson, J.-E., Borg, E. & Blom, S. The acoustic impedance change as a measure of stapedius muscle activity in man. A methodological study with electromyography. Acta Otolaryng, preprint. II. Borg, E. & Zakrisson, J.-E. Stapedius reflex and monaural masking. Acta Otolaryng, preprint. III. Zakrisson, J.-E. The role of the stapedius reflex in poststimulatory audi tory fatigue. Acta Otolaryng, preprint. IV. Borg, E. & Zakrisson, J.-E. The activity of the stapedius muscle in man during vocalization. Acta Otolaryng, accepted for publication. CONTENTS ABBREVIATIONS .......................................... 8 INTRODUCTION.............................................................................................. 9 MATERIAL..................................................................................................... -
A Molecular and Genetic Analysis of Otosclerosis
A molecular and genetic analysis of otosclerosis Joanna Lauren Ziff Submitted for the degree of PhD University College London January 2014 1 Declaration I, Joanna Ziff, confirm that the work presented in this thesis is my own. Where information has been derived from other sources, I confirm that this has been indicated in the thesis. Where work has been conducted by other members of our laboratory, this has been indicated by an appropriate reference. 2 Abstract Otosclerosis is a common form of conductive hearing loss. It is characterised by abnormal bone remodelling within the otic capsule, leading to formation of sclerotic lesions of the temporal bone. Encroachment of these lesions on to the footplate of the stapes in the middle ear leads to stapes fixation and subsequent conductive hearing loss. The hereditary nature of otosclerosis has long been recognised due to its recurrence within families, but its genetic aetiology is yet to be characterised. Although many familial linkage studies and candidate gene association studies to investigate the genetic nature of otosclerosis have been performed in recent years, progress in identifying disease causing genes has been slow. This is largely due to the highly heterogeneous nature of this condition. The research presented in this thesis examines the molecular and genetic basis of otosclerosis using two next generation sequencing technologies; RNA-sequencing and Whole Exome Sequencing. RNA–sequencing has provided human stapes transcriptomes for healthy and diseased stapes, and in combination with pathway analysis has helped identify genes and molecular processes dysregulated in otosclerotic tissue. Whole Exome Sequencing has been employed to investigate rare variants that segregate with otosclerosis in affected families, and has been followed by a variant filtering strategy, which has prioritised genes found to be dysregulated during RNA-sequencing. -
Hearing Screening Training Manual REVISED 12/2018
Hearing Screening Training Manual REVISED 12/2018 Minnesota Department of Health (MDH) Community and Family Health Division Maternal and Child Health Section 1 2 For more information, contact Minnesota Department of Health Maternal Child Health Section 85 E 7th Place St. Paul, MN 55164-0882 651-201-3760 [email protected] www.health.state.mn.us Upon request, this material will be made available in an alternative format such as large print, Braille or audio recording. 3 Revisions made to this manual are based on: Guidelines for Hearing Screening After the Newborn Period to Kindergarten Age http://www.improveehdi.org/mn/library/files/afternewbornperiodguidelines.pdf American Academy of Audiology, Childhood Screening Guidelines http://www.cdc.gov/ncbddd/hearingloss/documents/AAA_Childhood%20Hearing%2 0Guidelines_2011.pdf American Academy of Pediatrics (AAP), Hearing Assessment in Children: Recommendations Beyond Neonatal Screening http://pediatrics.aappublications.org/content/124/4/1252 4 Contents Introduction .................................................................................................................... 7 Audience ..................................................................................................................... 7 Purpose ....................................................................................................................... 7 Overview of hearing and hearing loss ............................................................................ 9 Sound, hearing, and hearing -
SENSORY MOTOR COORDINATION in ROBONAUT Richard Alan Peters
SENSORY MOTOR COORDINATION IN ROBONAUT 5 Richard Alan Peters 11 Vanderbilt University School of Engineering JSC Mail Code: ER4 30 October 2000 Robert 0. Ambrose Robotic Systems Technology Branch Automation, Robotics, & Simulation Division Engineering Directorate Richard Alan Peters II Robert 0. Ambrose SENSORY MOTOR COORDINATION IN ROBONAUT Final Report NASNASEE Summer Faculty Fellowship Program - 2000 Johnson Space Center Prepared By: Richard Alan Peters II, Ph.D. Academic Rank: Associate Professor University and Department: Vanderbilt University Department of Electrical Engineering and Computer Science Nashville, TN 37235 NASNJSC Directorate: Engineering Division: Automation, Robotics, & Simulation Branch: Robotic Systems Technology JSC Colleague: Robert 0. Ambrose Date Submitted: 30 October 2000 Contract Number: NAG 9-867 13-1 ABSTRACT As a participant of the year 2000 NASA Summer Faculty Fellowship Program, I worked with the engineers of the Dexterous Robotics Laboratory at NASA Johnson Space Center on the Robonaut project. The Robonaut is an articulated torso with two dexterous arms, left and right five-fingered hands, and a head with cameras mounted on an articulated neck. This advanced space robot, now dnven only teleoperatively using VR gloves, sensors and helmets, is to be upgraded to a thinking system that can find, in- teract with and assist humans autonomously, allowing the Crew to work with Robonaut as a (junior) member of their team. Thus, the work performed this summer was toward the goal of enabling Robonaut to operate autonomously as an intelligent assistant to as- tronauts. Our underlying hypothesis is that a robot can deveZop intelligence if it learns a set of basic behaviors ([.e., reflexes - actions tightly coupled to sensing) and through experi- ence learns how to sequence these to solve problems or to accomplish higher-level tasks. -
Study Guide Medical Terminology by Thea Liza Batan About the Author
Study Guide Medical Terminology By Thea Liza Batan About the Author Thea Liza Batan earned a Master of Science in Nursing Administration in 2007 from Xavier University in Cincinnati, Ohio. She has worked as a staff nurse, nurse instructor, and level department head. She currently works as a simulation coordinator and a free- lance writer specializing in nursing and healthcare. All terms mentioned in this text that are known to be trademarks or service marks have been appropriately capitalized. Use of a term in this text shouldn’t be regarded as affecting the validity of any trademark or service mark. Copyright © 2017 by Penn Foster, Inc. All rights reserved. No part of the material protected by this copyright may be reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, or by any information storage and retrieval system, without permission in writing from the copyright owner. Requests for permission to make copies of any part of the work should be mailed to Copyright Permissions, Penn Foster, 925 Oak Street, Scranton, Pennsylvania 18515. Printed in the United States of America CONTENTS INSTRUCTIONS 1 READING ASSIGNMENTS 3 LESSON 1: THE FUNDAMENTALS OF MEDICAL TERMINOLOGY 5 LESSON 2: DIAGNOSIS, INTERVENTION, AND HUMAN BODY TERMS 28 LESSON 3: MUSCULOSKELETAL, CIRCULATORY, AND RESPIRATORY SYSTEM TERMS 44 LESSON 4: DIGESTIVE, URINARY, AND REPRODUCTIVE SYSTEM TERMS 69 LESSON 5: INTEGUMENTARY, NERVOUS, AND ENDOCRINE S YSTEM TERMS 96 SELF-CHECK ANSWERS 134 © PENN FOSTER, INC. 2017 MEDICAL TERMINOLOGY PAGE III Contents INSTRUCTIONS INTRODUCTION Welcome to your course on medical terminology. You’re taking this course because you’re most likely interested in pursuing a health and science career, which entails proficiencyincommunicatingwithhealthcareprofessionalssuchasphysicians,nurses, or dentists. -
Sensory Change Following Motor Learning
A. M. Green, C. E. Chapman, J. F. Kalaska and F. Lepore (Eds.) Progress in Brain Research, Vol. 191 ISSN: 0079-6123 Copyright Ó 2011 Elsevier B.V. All rights reserved. CHAPTER 2 Sensory change following motor learning { k { { Andrew A. G. Mattar , Sazzad M. Nasir , Mohammad Darainy , and { } David J. Ostry , ,* { Department of Psychology, McGill University, Montréal, Québec, Canada { Shahed University, Tehran, Iran } Haskins Laboratories, New Haven, Connecticut, USA k The Roxelyn and Richard Pepper Department of Communication Sciences and Disorders, Northwestern University, Evanston, Illinois, USA Abstract: Here we describe two studies linking perceptual change with motor learning. In the first, we document persistent changes in somatosensory perception that occur following force field learning. Subjects learned to control a robotic device that applied forces to the hand during arm movements. This led to a change in the sensed position of the limb that lasted at least 24 h. Control experiments revealed that the sensory change depended on motor learning. In the second study, we describe changes in the perception of speech sounds that occur following speech motor learning. Subjects adapted control of speech movements to compensate for loads applied to the jaw by a robot. Perception of speech sounds was measured before and after motor learning. Adapted subjects showed a consistent shift in perception. In contrast, no consistent shift was seen in control subjects and subjects that did not adapt to the load. These studies suggest that motor learning changes both sensory and motor function. Keywords: motor learning; sensory plasticity; arm movements; proprioception; speech motor control; auditory perception. Introduction the human motor system and, likewise, to skill acquisition in the adult nervous system. -
Vestibular Neuritis and Labyrinthitis
Vestibular Neuritis and DISORDERS Labyrinthitis: Infections of the Inner Ear By Charlotte L. Shupert, PhD with contributions from Bridget Kulick, PT and the Vestibular Disorders Association INFECTIONS Result in damage to inner ear and/or nerve. ARTICLE 079 DID THIS ARTICLE HELP YOU? SUPPORT VEDA @ VESTIBULAR.ORG Vestibular neuritis and labyrinthitis are disorders resulting from an 5018 NE 15th Ave. infection that inflames the inner ear or the nerves connecting the inner Portland, OR 97211 ear to the brain. This inflammation disrupts the transmission of sensory 1-800-837-8428 information from the ear to the brain. Vertigo, dizziness, and difficulties [email protected] with balance, vision, or hearing may result. vestibular.org Infections of the inner ear are usually viral; less commonly, the cause is bacterial. Such inner ear infections are not the same as middle ear infections, which are the type of bacterial infections common in childhood affecting the area around the eardrum. VESTIBULAR.ORG :: 079 / DISORDERS 1 INNER EAR STRUCTURE AND FUNCTION The inner ear consists of a system of fluid-filled DEFINITIONS tubes and sacs called the labyrinth. The labyrinth serves two functions: hearing and balance. Neuritis Inflamation of the nerve. The hearing function involves the cochlea, a snail- shaped tube filled with fluid and sensitive nerve Labyrinthitis Inflamation of the labyrinth. endings that transmit sound signals to the brain. Bacterial infection where The balance function involves the vestibular bacteria infect the middle organs. Fluid and hair cells in the three loop-shaped ear or the bone surrounding semicircular canals and the sac-shaped utricle and Serous the inner ear produce toxins saccule provide the brain with information about Labyrinthitis that invade the inner ear via head movement. -
Vestibular Neuritis, Labyrinthitis, and a Few Comments Regarding Sudden Sensorineural Hearing Loss Marcello Cherchi
Vestibular neuritis, labyrinthitis, and a few comments regarding sudden sensorineural hearing loss Marcello Cherchi §1: What are these diseases, how are they related, and what is their cause? §1.1: What is vestibular neuritis? Vestibular neuritis, also called vestibular neuronitis, was originally described by Margaret Ruth Dix and Charles Skinner Hallpike in 1952 (Dix and Hallpike 1952). It is currently suspected to be an inflammatory-mediated insult (damage) to the balance-related nerve (vestibular nerve) between the ear and the brain that manifests with abrupt-onset, severe dizziness that lasts days to weeks, and occasionally recurs. Although vestibular neuritis is usually regarded as a process affecting the vestibular nerve itself, damage restricted to the vestibule (balance components of the inner ear) would manifest clinically in a similar way, and might be termed “vestibulitis,” although that term is seldom applied (Izraeli, Rachmel et al. 1989). Thus, distinguishing between “vestibular neuritis” (inflammation of the vestibular nerve) and “vestibulitis” (inflammation of the balance-related components of the inner ear) would be difficult. §1.2: What is labyrinthitis? Labyrinthitis is currently suspected to be due to an inflammatory-mediated insult (damage) to both the “hearing component” (the cochlea) and the “balance component” (the semicircular canals and otolith organs) of the inner ear (labyrinth) itself. Labyrinthitis is sometimes also termed “vertigo with sudden hearing loss” (Pogson, Taylor et al. 2016, Kim, Choi et al. 2018) – and we will discuss sudden hearing loss further in a moment. Labyrinthitis usually manifests with severe dizziness (similar to vestibular neuritis) accompanied by ear symptoms on one side (typically hearing loss and tinnitus). -
Inner Ear Infection (Otitis Interna) in Dogs
Hurricane Harvey Client Education Kit Inner Ear Infection (Otitis Interna) in Dogs My dog has just been diagnosed with an inner ear infection. What is this? Inflammation of the inner ear is called otitis interna, and it is most often caused by an infection. The infectious agent is most commonly bacterial, although yeast and fungus can also be implicated in an inner ear infection. If your dog has ear mites in the external ear canal, this can ultimately cause a problem in the inner ear and pose a greater risk for a bacterial infection. Similarly, inner ear infections may develop if disease exists in one ear canal or when a benign polyp is growing from the middle ear. A foreign object, such as grass seed, may also set the stage for bacterial infection in the inner ear. Are some dogs more susceptible to inner ear infection? Dogs with long, heavy ears seem to be predisposed to chronic ear infections that ultimately lead to otitis interna. Spaniel breeds, such as the Cocker spaniel, and hound breeds, such as the bloodhound and basset hound, are the most commonly affected breeds. Regardless of breed, any dog with a chronic ear infection that is difficult to control may develop otitis interna if the eardrum (tympanic membrane) is damaged as it allows bacteria to migrate down into the inner ear. "Dogs with long, heavy ears seem to bepredisposed to chronic ear infections that ultimately lead to otitis interna." Excessively vigorous cleaning of an infected external ear canal can sometimes cause otitis interna. Some ear cleansers are irritating to the middle and inner ear and can cause signs of otitis interna if the eardrum is damaged and allows some of the solution to penetrate too deeply. -
Hearing Loss, Vertigo and Tinnitus
HEARING LOSS, VERTIGO AND TINNITUS Jonathan Lara, DO April 29, 2012 Hearing Loss Facts S Men are more likely to experience hearing loss than women. S Approximately 17 percent (36 million) of American adults report some degree of hearing loss. S About 2 to 3 out of every 1,000 children in the United States are born deaf or hard-of-hearing. S Nine out of every 10 children who are born deaf are born to parents who can hear. Hearing Loss Facts S The NIDCD estimates that approximately 15 percent (26 million) of Americans between the ages of 20 and 69 have high frequency hearing loss due to exposure to loud sounds or noise at work or in leisure activities. S Only 1 out of 5 people who could benefit from a hearing aid actually wears one. S Three out of 4 children experience ear infection (otitis media) by the time they are 3 years old. Hearing Loss Facts S There is a strong relationship between age and reported hearing loss: 18 percent of American adults 45-64 years old, 30 percent of adults 65-74 years old, and 47 percent of adults 75 years old or older have a hearing impairment. S Roughly 25 million Americans have experienced tinnitus. S Approximately 4,000 new cases of sudden deafness occur each year in the United States. Hearing Loss Facts S Approximately 615,000 individuals have been diagnosed with Ménière's disease in the United States. Another 45,500 are newly diagnosed each year. S One out of every 100,000 individuals per year develops an acoustic neurinoma (vestibular schwannoma). -
Hearing Loss
Randal W. Swenson, M.D. Joshua G. Yorgason, M.D. David K. Palmer, M.D. Wesley R. Brown, M.D. John E. Butler, M.D. Nancy J. Stevenson, PA-C Justin D. Gull, M.D. ENT SPECIALISTS Kristin G. Hoopes, PA-C www.entslc.com Hearing Loss Approximately one in ten persons in the United may result from blockage of the ear canal (wax), States has some degree of hearing loss. Hearing is from a perforation (hole) in the ear drum, or from measured in decibels (dB), and a hearing level of 0- infection or disease of any of the three middle ear 25 dB is considered normal hearing. Your level is: bones. With a conductive loss only, the patient will never go deaf, but will always be able to hear, either Right ear _______ dB Left ear _______dB with reconstructive ear surgery or by use of a properly fitted hearing aid. Some patients who are Hearing Severity / % Loss not candidates for surgery, may benefit from a new 25 dB (normal).….0% 65dB(Severe)……...60% technology, the Baha (bone-anchored hearing aid). 35 dB (mild)……..15% 75dB(Severe)……...75% When there is a problem with the inner ear or 45 dB (moderate)..30% >85dB (Profound)..>90% nerve of hearing, a sensori-neural hearing loss occurs. This is most commonly from normal aging, Normal speech discrimination is 88-100%. Yours is: is usually worse in high frequencies, and can progress to total deafness. Noise exposure is another Right ear _______ % Left ear_______% common cause of high frequency hearing loss. Patients with sensori-neural hearing loss usually complain of difficulty hearing in loud environments.