CHAPTER 11 Skin, Hair, and Nails Color Variations in Light and Dark
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In Diagnosis Must Be Based on Clinical Signs and Symptoms. in This Paper
242 POST-GRADUATE MEDICAL JOURNAL August, 1938 Postgrad Med J: first published as 10.1136/pgmj.14.154.242 on 1 August 1938. Downloaded from SOME REMARKS ON DIFFERENTIAL DIAGNOSIS OF BLOOD DISEASES. By A. PINEY, M.D., M.R.C.P. (Assistant Physician, St. Mary's Hospital for Women and Children.) Differential diagnosis of blood diseases has been discussed time and again, but, as a rule, blood-pictures, rather than clinical features, have been taken into account, so that the impression has become widespread that the whole problem is one for the laboratory, rather than for the bed-side. It is obvious, however, that the first steps in diagnosis must be based on clinical signs and symptoms. In this paper, there- fore, certain outstanding clinical features of blood diseases, and various rather puzzling syndromes will be described. The outstanding external sign that leads the practitioner to consider the possi- bility of a blood disease is pallor, which is not quite so simple a state as is often supposed. It is, of course, well known that cutaneous pallor is not an infallible sign of anaemia, but it is often presumed that well-coloured mucous membranes are fairly good evidence that anaemia is not present. This is not necessarily true. The conjunctive may be bright pink in spite of anaemia, because mild inflammationProtected by copyright. may be present, masking the pallor. This is quite frequently due to irritation by eyelash dyes. Similarly, the finger-nails, which used to serve as a reliable index of pallor, are now found disguised with coloured varnish. -
Review Cutaneous Patterns Are Often the Only Clue to a a R T I C L E Complex Underlying Vascular Pathology
pp11 - 46 ABstract Review Cutaneous patterns are often the only clue to a A R T I C L E complex underlying vascular pathology. Reticulate pattern is probably one of the most important DERMATOLOGICAL dermatological signs of venous or arterial pathology involving the cutaneous microvasculature and its MANIFESTATIONS OF VENOUS presence may be the only sign of an important underlying pathology. Vascular malformations such DISEASE. PART II: Reticulate as cutis marmorata congenita telangiectasia, benign forms of livedo reticularis, and sinister conditions eruptions such as Sneddon’s syndrome can all present with a reticulate eruption. The literature dealing with this KUROSH PARSI MBBS, MSc (Med), FACP, FACD subject is confusing and full of inaccuracies. Terms Departments of Dermatology, St. Vincent’s Hospital & such as livedo reticularis, livedo racemosa, cutis Sydney Children’s Hospital, Sydney, Australia marmorata and retiform purpura have all been used to describe the same or entirely different conditions. To our knowledge, there are no published systematic reviews of reticulate eruptions in the medical Introduction literature. he reticulate pattern is probably one of the most This article is the second in a series of papers important dermatological signs that signifies the describing the dermatological manifestations of involvement of the underlying vascular networks venous disease. Given the wide scope of phlebology T and its overlap with many other specialties, this review and the cutaneous vasculature. It is seen in benign forms was divided into multiple instalments. We dedicated of livedo reticularis and in more sinister conditions such this instalment to demystifying the reticulate as Sneddon’s syndrome. There is considerable confusion pattern. -
Anemia in Children with Palmar Pallor Aged 02 Months to 05 Years
eCommons@AKU Department of Paediatrics and Child Health Division of Woman and Child Health 2-28-2017 Anemia in children with palmar pallor aged 02 months to 05 years Saroop Chand Farzana Shaikh Chetan Das Yasmeen Memon Mohammad Akbar Nizamani See next page for additional authors Follow this and additional works at: https://ecommons.aku.edu/ pakistan_fhs_mc_women_childhealth_paediatr Part of the Pediatrics Commons Authors Saroop Chand, Farzana Shaikh, Chetan Das, Yasmeen Memon, Mohammad Akbar Nizamani, and Zulfiqar Ali Qutrio Baloch IAJPS 2017, 4 (02), 290-295 Zulfiqar Ali Qutrio Baloch et al ISSN 2349-7750 CODEN (USA): IAJPBB ISSN: 2349-7750 INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES http://doi.org/10.5281/zenodo.345648 Available online at: http://www.iajps.com Research Article ANEMIA IN CHILDREN WITH PALMAR PALLOR AGED 02 MONTHS TO 05 YEARS Dr. Saroop Chand1, Dr. Farzana Shaikh1, Dr. Chetan Das1, Dr. Yasmeen Memon1, Dr. Mohammad Akbar Nizamani1 and *Dr. Zulfiqar Ali Qutrio Baloch2 1Department of pediatrics Liaquat University of Medical and Health Sciences (LUMHS). 2Brandon Regional Hospital, Brandon, Florida. Received: 10 February 2016 Accepted: 25 February 2017 Published: 28 February 2017 Absract: Objective: To determine the frequency of anemia in children with palmar pallor aged 02 months to 05 years Patients and Methods: This cross sectional descriptive study of six months (01-12-2012 to 31-05-2013) was conducted in the department of paediatrics at Liaquat University Hospital Hyderabad. All the children, from 02 months to 05 years, of either gender had palmar pallor on examination were recruited and evaluated for anemia by assessing the level of haemoglobin and categorized anemia as mild, moderate and severe. -
DERMATOLOGISTS SHARE SKIN CARE TIPS for PEOPLE with VITILIGO June Is Vitiligo Awareness Month
DERMATOLOGISTS SHARE SKIN CARE TIPS FOR PEOPLE WITH VITILIGO June is Vitiligo Awareness Month ROSEMONT, Ill. (June 11, 2019) — Millions of people worldwide have vitiligo, a condition that causes the skin to lose its natural color, resulting in patches of light skin. Although the white or light patches do not typically cause other symptoms, the condition can cause low self-esteem and depression in patients—of whom nearly half develop vitiligo before the age of 21. Although there is no cure for vitiligo, dermatologists from the American Academy of Dermatology say there is a lot patients can do at home to make vitiligo less visible and help prevent the condition from spreading. “Many people with vitiligo do not have any other signs or symptoms and feel completely healthy,” says board-certified dermatologist Anisha Patel, MD, FAAD. “However, the change in appearance caused by vitiligo can affect people emotionally, especially those who are younger and more concerned about their appearance. The good news is that there are things patients can do at home to make the condition more manageable.” To help vitiligo patients care for their skin, Dr. Patel recommends the following tips: 1. Protect your skin from the sun. Exposure to the sun’s harmful ultraviolet (UV) rays increases your risk of skin cancer, including melanoma, the deadliest form. Since vitiligo skin can burn more easily, it’s important to protect your skin whenever you’re outdoors. To do this, seek shade, wear protective clothing—including a lightweight, long-sleeved shirt, pants, a wide-brimmed hat and sunglasses—and apply sunscreen to all areas of the body not covered by clothing. -
Cerebellar Disease in the Dog and Cat
CEREBELLAR DISEASE IN THE DOG AND CAT: A LITERATURE REVIEW AND CLINICAL CASE STUDY (1996-1998) b y Diane Dali-An Lu BVetMed A thesis submitted for the degree of Master of Veterinary Medicine (M.V.M.) In the Faculty of Veterinary Medicine University of Glasgow Department of Veterinary Clinical Studies Division of Small Animal Clinical Studies University of Glasgow Veterinary School A p ril 1 9 9 9 © Diane Dali-An Lu 1999 ProQuest Number: 13815577 All rights reserved INFORMATION TO ALL USERS The quality of this reproduction is dependent upon the quality of the copy submitted. In the unlikely event that the author did not send a com plete manuscript and there are missing pages, these will be noted. Also, if material had to be removed, a note will indicate the deletion. uest ProQuest 13815577 Published by ProQuest LLC(2018). Copyright of the Dissertation is held by the Author. All rights reserved. This work is protected against unauthorized copying under Title 17, United States C ode Microform Edition © ProQuest LLC. ProQuest LLC. 789 East Eisenhower Parkway P.O. Box 1346 Ann Arbor, Ml 48106- 1346 GLASGOW UNIVERSITY lib ra ry ll5X C C ^ Summary SUMMARY________________________________ The aim of this thesis is to detail the history, clinical findings, ancillary investigations and, in some cases, pathological findings in 25 cases of cerebellar disease in dogs and cats which were presented to Glasgow University Veterinary School and Hospital during the period October 1996 to June 1998. Clinical findings were usually characteristic, although the signs could range from mild tremor and ataxia to severe generalised ataxia causing frequent falling over and difficulty in locomotion. -
Vitiligo to Predict How Much Pig- S Ment an Individual Will the Pigment Found in the Skin, Retina, and Hair of Human Beings Lose
ddiseasesanddisorders Vitiligo to predict how much pig- s ment an individual will The pigment found in the skin, retina, and hair of human beings lose. Its incidence is is called melanin and is produced in melanocyte cells. If these cells higher in people with thy- die or cannot form melanin, the result is a skin condition called roid conditions and some vitiligo, in which the skin becomes lighter or completely white in other metabolic diseases, patches, usually on the face, lips, hands, arms, legs, and genital but most patients are in areas. Because of the social effects of the change in appearance, good health and suffer no it is considered by many to be a skin disorder that has more soci- symptoms other than etal than medical significance. areas of pigment loss. Medical researchers are not sure what causes vitiligo, but some The first cases of 1803 engraving of man with vitiligo. believe it originates from both genetic and environmental factors. vitiligo were recorded in Vitiligo sometimes runs in families, and one study conducted by the religious texts such as the Bible and the Koran. University of Florida College of Medicine (Genes Immun. 2003, There are several treatment options for the disease. The easi- 4, 492–499) found that 20% of the relatives of vitiligo patients also est is disguising the patches with makeup, self-tanning com- have the disease—suggesting that some people are born with pounds, or skin dyes, which is considered a safe, albeit temporary, genes that make them more likely to way to make the patches less noticeable. -
History & Physical Format
History & Physical Format SUBJECTIVE (History) Identification name, address, tel.#, DOB, informant, referring provider CC (chief complaint) list of symptoms & duration. reason for seeking care HPI (history of present illness) - PQRST Provocative/palliative - precipitating/relieving Quality/quantity - character Region - location/radiation Severity - constant/intermittent Timing - onset/frequency/duration PMH (past medical /surgical history) general health, weight loss, hepatitis, rheumatic fever, mono, flu, arthritis, Ca, gout, asthma/COPD, pneumonia, thyroid dx, blood dyscrasias, ASCVD, HTN, UTIs, DM, seizures, operations, injuries, PUD/GERD, hospitalizations, psych hx Allergies Meds (Rx & OTC) SH (social history) birthplace, residence, education, occupation, marital status, ETOH, smoking, drugs, etc., sexual activity - MEN, WOMEN or BOTH CAGE Review Ever Feel Need to CUT DOWN Ever Felt ANNOYED by criticism of drinking Ever Had GUILTY Feelings Ever Taken Morning EYE OPENER FH (family history) age & cause of death of relatives' family diseases (CAD, CA, DM, psych) SUBJECTIVE (Review of Systems) skin, hair, nails - lesions, rashes, pruritis, changes in moles; change in distribution; lymph nodes - enlargement, pain bones , joints muscles - fractures, pain, stiffness, weakness, atrophy blood - anemia, bruising head - H/A, trauma, vertigo, syncope, seizures, memory eyes- visual loss, diplopia, trauma, inflammation glasses ears - deafness, tinnitis, discharge, pain nose - discharge, obstruction, epistaxis mouth - sores, gingival bleeding, teeth, -
FDA CVM Comprehensive ADE Report Listing for Sarolaner
CVM ADE Comprehensive Clinical Detail Report Listing Cumulative Date Range : 24-Feb-2016 -thru- 31-Jul-2018 Included 1932a cases = : True Included Medicated Feed cases = : False DRUG: SAROLANER Species: Cat Route of Administration: oral Sign: ACCIDENTAL EXPOSURE, Number of times reported: 41 Sign: SEIZURE NOS, Number of times reported: 25 Sign: VOMITING, Number of times reported: 15 Sign: TREMOR, Number of times reported: 10 Sign: HYPERSALIVATION, Number of times reported: 9 Sign: MUSCLE TREMOR, Number of times reported: 7 Sign: TWITCHING, Number of times reported: 6 Sign: LETHARGY, Number of times reported: 5 Sign: ANOREXIA, Number of times reported: 4 Sign: HIDING, Number of times reported: 4 Sign: PANTING, Number of times reported: 4 Sign: ATAXIA, Number of times reported: 3 Sign: BEHAVIOURAL DISORDER NOS, Number of times reported: 3 Sign: DROOLING, Number of times reported: 3 Sign: EMESIS, Number of times reported: 3 Sign: FOAMING AT THE MOUTH, Number of times reported: 3 Sign: HYPERAESTHESIA, Number of times reported: 3 Sign: HYPOTHERMIA, Number of times reported: 3 Sign: NOT EATING, Number of times reported: 3 Sign: SHAKING, Number of times reported: 3 Sign: ANXIETY, Number of times reported: 2 Sign: DEHYDRATION, Number of times reported: 2 Sign: HEAD TREMOR, Number of times reported: 2 Sign: HYPERPHOSPHATAEMIA, Number of times reported: 2 Sign: LATERAL RECUMBENCY, Number of times reported: 2 Sign: NEUROLOGICAL SIGNS NOS, Number of times reported: 2 Sign: ABNORMAL MOVEMENT NOS, Number of times reported: 1 Sign: ABNORMAL ULTRASOUND -
4 Edema in Childhood
Kidney International, Vol. 51, Suppl. 59 (1997). pp. S-100-S-104 (1) Red Hypo Ne] Liv Edema in childhood Ma Pre Sev SATOSHI HISANO, SEUNGHOON HAHN, NANCY B. KUEMMERLE, JAMES CM. CHAN, (2) Incr. and NATALE G. DESANTO Cardi He: h Pediatric Nephrology Division, Virginia Commonwealth University's Medical College of Virginia, Richmond, Virginia, USA, and Divisione di Nefrologia Art dell' Adulto e del Bambino, Seconda Universita'degli Studi di Napoli, Naples, Italy Renal Act ACt Idiops Fan Edema in childhood. There are two types of edema: localized edema sympathetic nervous system (SNS) activity; and (3) antidiuretic Nor and generalized edema. The causes ofgeneralized edema in childhoodare hormone (ADH) release [4-6]. These forces and perhaps as yet diverse. Formation of generalizededema involves retention of sodium and Prej unidentified factors give rise to the consequential water and water in the kidney. The treatment of generalized edema depends on the (3) Incre primary etiology. Supportive nutritional and medicaltherapies are needed sodium retention, which promotes the development of edema, Allerg to prevent further edema. These and related features of edema in The sodium and water retention leads to further decreased Vascu childhood are discussed in this review. den plasma oncotic pressure, setting up a vicious cycle perpetuating dise the edema formation. The movement of water from intracellular space to interstitial space by itself also contributes to the devel opment of edema formation [1, 3]. Edema can be defined as the presence of excess fluid in the In contrast, the mechanism of "overfilling edema" is expanded interstitial space of the body. Edema is divided into two types, extracellular volume that results from primary renal sodium localized edema and generalized edema. -
Skin Tone and Stratification in the Black Community Author(S): Verna M
Skin Tone and Stratification in the Black Community Author(s): Verna M. Keith and Cedric Herring Source: The American Journal of Sociology, Vol. 97, No. 3 (Nov., 1991), pp. 760-778 Published by: The University of Chicago Press Stable URL: http://www.jstor.org/stable/2781783 Accessed: 23/04/2009 17:58 Your use of the JSTOR archive indicates your acceptance of JSTOR's Terms and Conditions of Use, available at http://www.jstor.org/page/info/about/policies/terms.jsp. JSTOR's Terms and Conditions of Use provides, in part, that unless you have obtained prior permission, you may not download an entire issue of a journal or multiple copies of articles, and you may use content in the JSTOR archive only for your personal, non-commercial use. Please contact the publisher regarding any further use of this work. Publisher contact information may be obtained at http://www.jstor.org/action/showPublisher?publisherCode=ucpress. Each copy of any part of a JSTOR transmission must contain the same copyright notice that appears on the screen or printed page of such transmission. JSTOR is a not-for-profit organization founded in 1995 to build trusted digital archives for scholarship. We work with the scholarly community to preserve their work and the materials they rely upon, and to build a common research platform that promotes the discovery and use of these resources. For more information about JSTOR, please contact [email protected]. The University of Chicago Press is collaborating with JSTOR to digitize, preserve and extend access to The American Journal of Sociology. -
What Is Albinism?
INFORMATION ABOUT ALBINISM What Is Albinism? Albinism is an inherited genetic condition that reduces the amount of melanin pigment formed in the skin, hair and/ or eyes. Albinism occurs in all racial and ethnic groups throughout the world. In the U.S., approximately one in 18,000 to 20,000 people has some type of albinism. In other parts of the world, the occurrence can be as high as one in 3,000. Most children with albinism are born to parents whose hair and eye color are typical for their ethnic backgrounds. A common myth is that people with albinism have red eyes. Although lighting conditions can allow the blood vessels at the back of the eye to be seen, which can cause the eyes to look reddish or violet, most people with albinism have blue eyes, and some have hazel or brown eyes. There are Photo courtesy of Positive Exposure, Rick Guidotti different types of albinism and the amount vision in a variety of ways and are able to of pigment in the eyes varies. However, perform innumerable activities such as vision problems are associated with all reading, riding a bike or fishing. Some have types of albinism. sufficient vision to drive a car. Vision Considerations Dermatological Considerations People with albinism have vision problems Because most people with albinism that are not correctable with eyeglasses, have fair complexions, it’s important to and many have low vision. It’s the abnormal avoid sun damage to the skin and eyes development of the retina and abnormal by taking precautions such as wearing patterns of nerve connections between sunscreen or sunblock, hats, sunglasses and the eye and the brain that cause vision sun-protective clothing. -
Human Pigmentation Variation: Evolution, Genetic Basis, and Implications for Public Health
YEARBOOK OF PHYSICAL ANTHROPOLOGY 50:85–105 (2007) Human Pigmentation Variation: Evolution, Genetic Basis, and Implications for Public Health Esteban J. Parra* Department of Anthropology, University of Toronto at Mississauga, Mississauga, ON, Canada L5L 1C6 KEY WORDS pigmentation; evolutionary factors; genes; public health ABSTRACT Pigmentation, which is primarily deter- tic interpretations of human variation can be. It is erro- mined by the amount, the type, and the distribution of neous to extrapolate the patterns of variation observed melanin, shows a remarkable diversity in human popu- in superficial traits such as pigmentation to the rest of lations, and in this sense, it is an atypical trait. Numer- the genome. It is similarly misleading to suggest, based ous genetic studies have indicated that the average pro- on the ‘‘average’’ genomic picture, that variation among portion of genetic variation due to differences among human populations is irrelevant. The study of the genes major continental groups is just 10–15% of the total underlying human pigmentation diversity brings to the genetic variation. In contrast, skin pigmentation shows forefront the mosaic nature of human genetic variation: large differences among continental populations. The our genome is composed of a myriad of segments with reasons for this discrepancy can be traced back primarily different patterns of variation and evolutionary histories. to the strong influence of natural selection, which has 2) Pigmentation can be very useful to understand the shaped the distribution of pigmentation according to a genetic architecture of complex traits. The pigmentation latitudinal gradient. Research during the last 5 years of unexposed areas of the skin (constitutive pigmenta- has substantially increased our understanding of the tion) is relatively unaffected by environmental influences genes involved in normal pigmentation variation in during an individual’s lifetime when compared with human populations.