Basic Histology (23 Questions): Oral Histology (16 Questions
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Ono -- PTH-Pthrp Receptor Signaling in Osterix-Expressing Progenitors.Pdf
3/27/14 Root forma)on Cementum Dentin Cementoblast Odontoblast Role of PTH/PTHrP Receptor Signaling on Root Epithelial rests Formaon of Malassez (ERM) Dental Wanida Ono papilla cells AGE Orthodon;cs, Department of Developmental Biology, Harvard School of Dental Medicine Endocrine Unit, MassachuseLs General Hospital and Harvard Medical School Dental follicle cells Hertwig’s epithelial root sheath (HERS) Osterix PTHrP-PPR system • Transcripon factor essen;al to osteoblast differen;aon PTHrP (Nakashima K et al. 2002) PTH/PTHrP receptor (PPR) • Expressed in odontoblasts and alveolar osteoblasts during Gαs Gq tooth development (Chen S et al. 2009) • Controls cellular cementum formaon (Cao Z et al. 2012) • Mediates epithelial-mesenchymal interacons • Osterix-expressing precursors in the perichondrium move • PTHrP is expressed in enamel epithelia/HERS? to bone marrow and become osteoblasts during fetal • PPR is expressed in dental mesenchymes development (Maes C, Kronenberg HM et al. 2010) (Beck et al 1995; Lee Deeds and Segre 1995; Liu et al 1998) • PTHrP is required for tooth erup;on in mice (Philbrick WM, Karaplis AC et al. PNAS 1998) Osterix+ Root-forming • PPR haploinsufficiency is associated with primary cells progenitors failure of tooth erup;on (PFE) in humans ? (Decker E, Weber BH et al. Am J Hum Gen 2008) PTHrP expression paern during root morphogenesis Aims of this study PTHrPLacZ/+ x40 P7 P14 P49 • Iden;fy how osterix-expressing progenitors contribute to murine root morphogenesis • Understand how PTH/PTHrP receptor signal regulates root-forming progenitors PTHrP-LacZ x200 P7 x400 P14 ? PTHrP Epithelial root sheath PPR PTHrP-LacZ Osx+ progenitors Odontoblast PTHrP par;cipates in ……. -
Experimental Induction of Odontoblast Differentiation and Stimulation During Preparative Processes
Cells and Materials Volume 3 Number 2 Article 8 1993 Experimental Induction of Odontoblast Differentiation and Stimulation During Preparative Processes H. Lesot Institut de Biologie Médicale C. Begue-Kirn Institut de Biologie Médicale M. D. Kubler Institut de Biologie Médicale J. M. Meyer Institut de Biologie Médicale A. J. Smith Dental School, Birmingham See next page for additional authors Follow this and additional works at: https://digitalcommons.usu.edu/cellsandmaterials Part of the Biomedical Engineering and Bioengineering Commons Recommended Citation Lesot, H.; Begue-Kirn, C.; Kubler, M. D.; Meyer, J. M.; Smith, A. J.; Cassidy, N.; and Ruch, J. V. (1993) "Experimental Induction of Odontoblast Differentiation and Stimulation During Preparative Processes," Cells and Materials: Vol. 3 : No. 2 , Article 8. Available at: https://digitalcommons.usu.edu/cellsandmaterials/vol3/iss2/8 This Article is brought to you for free and open access by the Western Dairy Center at DigitalCommons@USU. It has been accepted for inclusion in Cells and Materials by an authorized administrator of DigitalCommons@USU. For more information, please contact [email protected]. Experimental Induction of Odontoblast Differentiation and Stimulation During Preparative Processes Authors H. Lesot, C. Begue-Kirn, M. D. Kubler, J. M. Meyer, A. J. Smith, N. Cassidy, and J. V. Ruch This article is available in Cells and Materials: https://digitalcommons.usu.edu/cellsandmaterials/vol3/iss2/8 Cells and Materials, Vol. 3, No. 2, 1993 (Pages201-217) 1051-6794/93$5. 00 +. 00 Scanning Microscopy International, Chicago (AMF O'Hare), IL 60666 USA EXPERIMENTAL INDUCTION OF ODONTOBLAST DIFFERENTIATION AND STIMULATION DURING REPARATIVE PROCESSES 1 1 1 2 2 1 H. -
Selecting Different Approaches for Palate and Pharynx Surgery
SPECIAL ISSUE 4: INVITED ARTICLE Selecting Different Approaches for Palate and Pharynx Surgery: Palatopharyngeal Arch Staging System Rodolfo Lugo-Saldaña1 , Karina Saldívar-Ponce2 , Irina González-Sáez3 , Daniela Hernández-Sirit4 , Patricia Mireles-García5 ABSTRACT The examination of the anatomical structures involved in the upper airway collapse in patients with the obstructive sleep apnea-hypopnea syndrome (OSAHS) is a key for integrated evaluation of patients. Our proposal is for a noninvasive classification system that guides us about the presence of anatomical differences between the palatopharyngeal muscle (PFM). The functions of the PFM are narrowing the isthmus, descending the palate, and raising the larynx during swallowing; these characteristics give the PFM a special role in the collapse of the lateral pharyngeal wall. Complete knowledge of the anatomy and classification of different variants can guide us to choose the appropriate surgical procedures for the lateral wall collapse. Until now there is not a consensus about description of the trajectory or anatomical variants of the PFM into oropharynx, the distance between both muscles, and the muscle tone. Here we also present the relationship between the lateral wall surgeries currently available (lateral pharyngoplasty by Cahali, expansion sphincteroplasty by Pang, relocation pharyngoplasty by Li, Roman blinds pharyngoplasty by Mantovani, and barbed sutures pharyngoplasty by Vicini) with the proposed classification of the palatopharyngeal arch staging system (PASS). Keywords: -
Cell Biology and Fundamentals in Histology - En-Cours-2018-Liepr1004 Liepr1004 Cell Biology and Fundamentals in 2018 Histology
Université catholique de Louvain - Cell biology and fundamentals in histology - en-cours-2018-liepr1004 liepr1004 Cell biology and fundamentals in 2018 histology 5 credits 45.0 h Q2 Teacher(s) Behets Wydemans Catherine ;Henriet Patrick ; Language : French Place of the course Louvain-la-Neuve Main themes The major themes are : - Characteristics common to all living species - The human cell, its functioning and division - Classical, evolutive and molecular genetics - Cellular bases in sexual reproduction - The differents cell types and their organisation in tissues - The major steps in human embryonic development Aims By the end of the module, students should understand the bases of unicity and diversity in the living world. They will know the structure and functioning of human cell and genome as well as the mechanisms of 1 cell division and embryonic development. Moreover, they will know the structure of the major types of human tissues. - - - - The contribution of this Teaching Unit to the development and command of the skills and learning outcomes of the programme(s) can be accessed at the end of this sheet, in the section entitled “Programmes/courses offering this Teaching Unit”. Content (auteurs - titulaires actuels) : P. Henriet and Ph. van den Bosch de Aguilar 1. UNICITY IN THE LIVING WORLD 2. THE HUMAN CELL 3. DIVERSITY IN THE LIVING WORLD 4. MOLECULAR GENETICS 5. CELL DIVISION 6. GAMETOGENESIS AND FERTILIZATION 7. INTRODUCTION TO HUMAN EMBRYOLOGY Histology 1. EPITHELIAL TISSUE 2. CONNECTIVE TISSUE 3. BLOOD TISSUE 4. MUSCLE TISSUE -
Journal of Dental Research
Journal of Dental Research http://jdr.sagepub.com/ Cell Differentiation and Matrix Organization in Engineered Teeth A. Nait Lechguer, M.L. Couble, N. Labert, S. Kuchler-Bopp, L. Keller, H. Magloire, F. Bleicher and H. Lesot J DENT RES 2011 90: 583 originally published online 4 February 2011 DOI: 10.1177/0022034510391796 The online version of this article can be found at: http://jdr.sagepub.com/content/90/5/583 Published by: http://www.sagepublications.com On behalf of: International and American Associations for Dental Research Additional services and information for Journal of Dental Research can be found at: Email Alerts: http://jdr.sagepub.com/cgi/alerts Subscriptions: http://jdr.sagepub.com/subscriptions Reprints: http://www.sagepub.com/journalsReprints.nav Permissions: http://www.sagepub.com/journalsPermissions.nav >> Version of Record - Apr 13, 2011 OnlineFirst Version of Record - Feb 4, 2011 What is This? Downloaded from jdr.sagepub.com at Service Commun de la Documentation Université de Strasbourg on September 6, 2013 For personal use only. No other uses without permission. © 2011 International & American Associations for Dental Research RESEARCH REPORTS Biomaterials & Bioengineering A. Nait Lechguer1,2, M.L. Couble3,4, N. Labert3,4, S. Kuchler-Bopp1,2, Cell Differentiation and L. Keller1,2, H. Magloire3,4, F. Bleicher3,4, Matrix Organization in and H. Lesot1,2* Engineered Teeth 1INSERM UMR 977, Faculté de Médecine, 11, rue Humann, F-67085 Strasbourg, France; 2Dental School, University of Strasbourg, Strasbourg, France; 3Université de Lyon, Faculté d’Odontologie, Rue Guillaume Paradin, F-69372 Lyon Cedex 08, France; and 4IGFL, CNRS UMR 5242, Ecole Normale Supérieure, 46 Allée d’Italie, 69364, Lyon Cedex 08, France; *corresponding author, [email protected] J Dent Res 90(5):583-589, 2011 ABSTRACT InTRODuCTIOn Embryonic dental cells were used to check a series of criteria to be achieved for tooth engineering. -
Immune Response and Histology of Humoral Rejection in Kidney
Document downloaded from http://www.elsevier.es, day 23/05/2017. This copy is for personal use. Any transmission of this document by any media or format is strictly prohibited. n e f r o l o g i a 2 0 1 6;3 6(4):354–367 Revista de la Sociedad Española de Nefrología www.revistanefrologia.com Review Immune response and histology of humoral rejection in kidney transplantation a,∗ a b a Miguel González-Molina , Pedro Ruiz-Esteban , Abelardo Caballero , Dolores Burgos , a c a a Mercedes Cabello , Miriam Leon , Laura Fuentes , Domingo Hernandez a Nephrology Department, Regional University Hospital of Malaga, Malaga University, IBIMA, REDINREN RD12/0021/0015, Malaga, Spain b Immunology Department, Regional University Hospital of Malaga, Malaga University, IBIMA, REDINREN RD12/0021/0015, Malaga, Spain c Pathology Department, Regional University Hospital of Malaga, Malaga University, IBIMA, REDINREN RD12/0021/0015, Malaga, Spain a r t i c l e i n f o a b s t r a c t Article history: The adaptive immune response forms the basis of allograft rejection. Its weapons are direct Received 4 June 2015 cellular cytotoxicity, identified from the beginning of organ transplantation, and/or anti- Accepted 26 March 2016 bodies, limited to hyperacute rejection by preformed antibodies and not as an allogenic Available online 3 June 2016 response. This resulted in allogenic response being thought for decades to have just a cellu- lar origin. But the experimental studies by Gorer demonstrating tissue damage in allografts Keywords: due to antibodies secreted by B lymphocytes activated against polymorphic molecules were Immune response disregarded. -
Abbreviations - Diagnosis
Abbreviations - Diagnosis AB abrasion AT attrition CA caries CFL cleft lip CFP cleft palate CLL cervical line lesion - See TR CMO craniomandibular osteopathy DT deciduous (primary) tooth DTC dentigerous cyst E enamel E/D enamel defect E/H enamel hypocalcification or hypoplasia FB foreign body FORL feline odontoclastic resorptive lesion - See TR FX fracture (tooth or jaw) G granuloma G/B buccal granuloma (cheek chewing lesion) G/L sublingual granuloma (tongue chewing lesion) G/E/L eosinophilic granuloma - lip G/E/P eosinophilic granuloma - palate G/E/T eosinophilic granuloma - tongue GH gingival hyperplasia GR gingival recession LAC laceration LAC/B laceration buccal (cheek) LAC/L laceration lip LAC/T laceration tongue MAL malocclusion MAL/1 class 1 malocclusion (neutroclusion - normal jaw relationship, specific teeth are incorrectly positioned) MAL/2 class 2 malocclusion (mandibular distoclusion - mandible shorter than maxilla) MAL/3 class 3 malocclusion (mandibular mesioclusion - maxilla shorter than mandible) BV buccoversion (crown directed towards cheek) CXB caudal crossbite DV distoversion (crown directed away from midline of dental arch) LABV labioversion (crown directed towards lip) LV linguoversion (crown directed towards tongue) MV mesioversion (crown directed towards midline of dental arch) OB open bite RXB rostral crossbite MN mandible or mandibular MN/FX mandibular fracture MX maxilla or maxillary MX/FX maxillary fracture OM oral mass OM/AD adenocarcinoma OM/EPA acanthomatous ameloblastoma (epulis) OM/EPF fibromatous epulis -
6 Development of the Teeth: Root and Supporting Structures Nagat M
AVERY Chap.06 27-11-2002 10:09 Pagina 108 108 II Development of the Teeth and Supporting Structures 6 Development of the Teeth: Root and Supporting Structures Nagat M. ElNesr and James K. Avery Chapter Outline Introduction Introduction... 108 Objectives... 108 Root development is initiated through the contributions Root Sheath Development... 109 of the cells originating from the enamel organ, dental Single-Root Formation... 110 papilla, and dental follicle. The cells of the outer enamel Multiple-Root Formation... 111 epithelium contact the inner enamel epithelium at the Root Formation Anomalies... 112 base of the enamel organ, the cervical loop (Figs. 6.1 and Fate of the Epithelial Root Sheath (Hertwig's Sheath)... 113 6.2A). Later, with crown completion, the cells of the cer- Dental Follicle... 114 vical loop continue to grow away from the crown and Development of (Intermediate) Cementum... 116 become root sheath cells (Figs. 6.2B and 6.3). The inner Cellular and Acellular Cementum... 116 root sheath cells cause root formation by inducing the Development of the Periodontal Ligament... 117 adjacent cells of the dental papilla to become odonto- Development of the Alveolar Process... 119 blasts, which in turn will form root dentin. The root Summary... 121 sheath will further dictate whether the tooth will have Self-Evaluation Review... 122 single or multiple roots. The remainder of the cells of the dental papilla will then become the cells of the root pulp.The third compo- nent in root formation, the dental follicle, is the tissue that surrounds the enamel organ, the dental papilla, and the root. -
Lecture 2 – Bone
Oral Histology Summary Notes Enoch Ng Lecture 2 – Bone - Protection of brain, lungs, other internal organs - Structural support for heart, lungs, and marrow - Attachment sites for muscles - Mineral reservoir for calcium (99% of body’s) and phosphorous (85% of body’s) - Trap for dangerous minerals (ex:// lead) - Transduction of sound - Endocrine organ (osteocalcin regulates insulin signaling, glucose metabolism, and fat mass) Structure - Compact/Cortical o Diaphysis of long bone, “envelope” of cuboid bones (vertebrae) o 10% porosity, 70-80% calcified (4x mass of trabecular bone) o Protective, subject to bending/torsion/compressive forces o Has Haversian system structure - Trabecular/Cancellous o Metaphysis and epiphysis of long bone, cuboid bone o 3D branching lattice formed along areas of mechanical stress o 50-90% porosity, 15-25% calcified (1/4 mass of compact bone) o High surface area high cellular activity (has marrow) o Metabolic turnover 8x greater than cortical bone o Subject to compressive forces o Trabeculae lined with endosteum (contains osteoprogenitors, osteoblasts, osteoclasts) - Woven Bone o Immature/primitive, rapidly growing . Normally – embryos, newborns, fracture calluses, metaphyseal region of bone . Abnormally – tumors, osteogenesis imperfecta, Pagetic bone o Disorganized, no uniform orientation of collagen fibers, coarse fibers, cells randomly arranged, varying mineral content, isotropic mechanical behavior (behavior the same no matter direction of applied force) - Lamellar Bone o Mature bone, remodeling of woven -
Specialized Stem Cell Niche Enables Repetitive Renewal of Alligator Teeth
Specialized stem cell niche enables repetitive renewal PNAS PLUS of alligator teeth Ping Wua, Xiaoshan Wua,b, Ting-Xin Jianga, Ruth M. Elseyc, Bradley L. Templed, Stephen J. Diverse, Travis C. Glennd, Kuo Yuanf, Min-Huey Cheng,h, Randall B. Widelitza, and Cheng-Ming Chuonga,h,i,1 aDepartment of Pathology, University of Southern California, Los Angeles, CA 90033; bDepartment of Oral and Maxillofacial Surgery, Xiangya Hospital, Central South University, Hunan 410008, China; cLouisiana Department of Wildlife and Fisheries, Rockefeller Wildlife Refuge, Grand Chenier, LA 70643; dEnvironmental Health Science and eDepartment of Small Animal Medicine and Surgery, University of Georgia, Athens, GA 30602; fDepartment of Dentistry and iResearch Center for Wound Repair and Regeneration, National Cheng Kung University, Tainan City 70101, Taiwan; and gSchool of Dentistry and hResearch Center for Developmental Biology and Regenerative Medicine, National Taiwan University, Taipei 10617, Taiwan Edited by Edward M. De Robertis, Howard Hughes Medical Institute/University of California, Los Angeles, CA, and accepted by the Editorial Board March 28, 2013 (received for review July 31, 2012) Reptiles and fish have robust regenerative powers for tooth renewal. replaced from the dental lamina connected to the lingual side of However, extant mammals can either renew their teeth one time the deciduous tooth (15). Human teeth are only replaced one time; (diphyodont dentition) or not at all (monophyodont dentition). however, a remnant of the dental lamina still exists (16) and may Humans replace their milk teeth with permanent teeth and then become activated later in life to form odontogenic tumors (17). lose their ability for tooth renewal. -
Satellitosis, a Crosstalk Between Neurons, Vascular Structures and Neoplastic Cells in Brain Tumours; Early Manifestation of Invasive Behaviour
cancers Review Satellitosis, a Crosstalk between Neurons, Vascular Structures and Neoplastic Cells in Brain Tumours; Early Manifestation of Invasive Behaviour Prospero Civita 1,2,* , Ortenzi Valerio 3 , Antonio Giuseppe Naccarato 3 , Mark Gumbleton 2 and Geoffrey J. Pilkington 1,2,4,* 1 Brain Tumour Research Centre, Institute of Biological and Biomedical Sciences (IBBS), School of Pharmacy and Biomedical Sciences, University of Portsmouth, Portsmouth PO1 2DT, UK 2 School of Pharmacy and Pharmaceutical Sciences, College of Biomedical and Life Sciences, Cardiff University, Cardiff CF10 3NB, UK; gumbleton@cardiff.ac.uk 3 Department of Translational Research and New Technologies in Medicine and Surgery, Pisa University Hospital, 56100 Pisa, Italy; [email protected] (O.V.); [email protected] (A.G.N.) 4 Division of Neuroscience, Department of Basic and Clinical Neuroscience, Institute of Psychiatry & Neurology, King’s College London, London SE5 9RX, UK * Correspondence: CivitaP@cardiff.ac.uk (P.C.); geoff[email protected] (G.J.P.) Received: 9 November 2020; Accepted: 4 December 2020; Published: 11 December 2020 Simple Summary: This article reviews the concept of cellular satellitosis as originally described histologically by Santiago Ramón y Cajal in 1899 and Hans Joachim Scherer, more specifically in the context of glioblastoma invasiveness, during the early part of the 20th century. With the advent of new and emerging molecular technologies in the 21st century, the significance of both vascular and neuronal satellitosis by neoplastic cells offers intriguing possibilities into further clarifying the development, pathobiology and therapy of malignant glioma through closer investigation into the nature of these histological hallmarks. -
Study Guide Medical Terminology by Thea Liza Batan About the Author
Study Guide Medical Terminology By Thea Liza Batan About the Author Thea Liza Batan earned a Master of Science in Nursing Administration in 2007 from Xavier University in Cincinnati, Ohio. She has worked as a staff nurse, nurse instructor, and level department head. She currently works as a simulation coordinator and a free- lance writer specializing in nursing and healthcare. All terms mentioned in this text that are known to be trademarks or service marks have been appropriately capitalized. Use of a term in this text shouldn’t be regarded as affecting the validity of any trademark or service mark. Copyright © 2017 by Penn Foster, Inc. All rights reserved. No part of the material protected by this copyright may be reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, or by any information storage and retrieval system, without permission in writing from the copyright owner. Requests for permission to make copies of any part of the work should be mailed to Copyright Permissions, Penn Foster, 925 Oak Street, Scranton, Pennsylvania 18515. Printed in the United States of America CONTENTS INSTRUCTIONS 1 READING ASSIGNMENTS 3 LESSON 1: THE FUNDAMENTALS OF MEDICAL TERMINOLOGY 5 LESSON 2: DIAGNOSIS, INTERVENTION, AND HUMAN BODY TERMS 28 LESSON 3: MUSCULOSKELETAL, CIRCULATORY, AND RESPIRATORY SYSTEM TERMS 44 LESSON 4: DIGESTIVE, URINARY, AND REPRODUCTIVE SYSTEM TERMS 69 LESSON 5: INTEGUMENTARY, NERVOUS, AND ENDOCRINE S YSTEM TERMS 96 SELF-CHECK ANSWERS 134 © PENN FOSTER, INC. 2017 MEDICAL TERMINOLOGY PAGE III Contents INSTRUCTIONS INTRODUCTION Welcome to your course on medical terminology. You’re taking this course because you’re most likely interested in pursuing a health and science career, which entails proficiencyincommunicatingwithhealthcareprofessionalssuchasphysicians,nurses, or dentists.