15th International GERLI Lipidomics Meeting “Biodiversity of lipid species – Benefit for nutrition and Effects on healtH” September 30 to October 2 – University of Technology of Compiègne Sunday 29 September 2019 OPENING COCKTAIL AT T’AIM HOTEL (70 A Pont Neuf, 60280 Margny-lès-Compiègne) - 19:15 Scientific program and sessions: Monday, September 30th, 2019 – Morning session 8h:00 – Check in 9:15 - Opening of the congress – President of UTC 9:30 – President of the GERLI, President of Region Hauts-De-France, … Session 1 – Unusual fatty acids and lipid species with interesting physiological effects. Chairmen: Enrique Martinez-Forces (Instituto de la Grasa, Séville, Spain), Frederic Domergue (CNRS, Villenave d’Ornon, France), 09:45-10:15 Keynote : Yvan Larondelle (Université Catholique de Louvain, Belgium). Conjugated fatty acids: new natural ways to develop health-promoting foods. 10:15-10:30 Todd Fox (University of Virginia, Charlottesville, USA) Regulation of Obesity by Nervonic Acid 10:30-10:45 Molka Zoghlami (Univ Tunis El Manar, El Manar Tunis, Tunisia) Interfacial behavior of LDL (Low density Lipoproteins) and HDL (High density Lipoproteins): links with cardiovascular risk? 10h45 - Coffee break – Posters 11:00-11:30 Keynote : Ed Cahoon (University of Nebraska, USA). Probing Fatty Acid Natural Diversity for Enhancement of Plant Oils. 11:30-11:45 Fabrice Rebeillé (lnstitut de Recherche Interdisciplinaire, Grenoble, France) Thraustochytrids: a promising source of DHA and squalene 11:45-12:00 Wancheng Sun (Qinghai University, Xining, China). The lipidomics phospholipids and Branched Chain Fatty Acids from Yak Ghee on Gene Expression of Lipids Metabolism. 12:00-12:15 Cécile Vors (Institute of Nutrition and Functional Foods, Quebec, Canada) Differential associations between plasma oxylipins and lipoprotein kinetics after DHA and EPA supplementation: the ComparED study 12:15-12:30 Toshihide Kobayashi (Riken Advanced Science Institute, Wako Saitama, Japan) Formation of tubules and helical ribbons by ceramide phosphoethanolamine- containing membranes. 12h30 – Lunch 13h30 – 14h30 - Posters Monday, September 30th, 2019 – Afternoon session Session 2 – Lipids and inflammatory mechanisms – Diseases and prevention Chairmen: Thierry Durand (IBMM, Université de Montpellier, France), Nathalie Bernoud- Hubac (Laboratoire CarMeN, Villeurbanne, France), 14h30-15:00 Keynote : Jesmond Dalli – (William Harvey Research Institute, London, UK). Immunoresolvants in the maintenance of homeostasis and the control of exuberant inflammation. 15:00-15:15 Thomas Laval (Institut Pasteur, Paris, France). Infection-driven rewiring of fatty acid metabolism helps macrophages contain Mycobacterium tuberculosis growth. 15:15-15:30 Katarzyna Duda (Leibniz lung Cente, Borstel, Germany ). Lipid Mediators from Timothy Grass Pollen Contribute to the Effector Phase of Allergy and Prime Dendritic Cells for Glycolipid Presentation. 15:30-15:45 Romain Ferru Clement (La Rochelle University-UMR 7266, La Rochelle, France) Comprehensive serum lipidomics & Crohn's Disease biomarkers. 15 :45 Coffee break – Posters 16:15-16:45 Keynote : Martin Giera (Leiden University Medical Center, The Netherlands). Boosting endogenous lipid mediator biosynthesis. 16:45-17:00 Romain Colas (William Harvey Research Institute, London, UK). Impaired Production and Diurnal Regulation of Vascular RvDn-3 DPA Increase Systemic Inflammation and Cardiovascular Disease. 17:00-17:15 Verena Poinsot (INSERM, Toulouse, France). Lipidomic of cardiac stromal exosomes: a heart failure signaling? 17:15-17:30 Céline Crauste (Institut des Biomolécules Max Mousseron, Montpellier, France). Polyunsaturated fatty acid conjugated to polyphenol reduces light induced ` photoreceptors degeneration: from synthesis to in vitro and in vivo study. 17:30-17:45 Arieh Moussaieff, (Institute for Drug Research, Jerusalem, Israel). A shift in follicular fluid from triacylglycerols to membrane lipids is associated with positive pregnancy outcome. 17:45 - Session : Poster presentations - Short talks of 1 min 18:30 - GERLI and SFEL General Assembly Tuesday, October 1st, 2019 – Morning session Session 3 – Lipids and vectorization Chairmen: Vincent Jannin (Capsugel Lonza SAS, France), Sandrine Morandat (BMBI, UTC, France) 9 :00-9:30 Keynote : Ben Boyd (Monash Institute of Pharmaceutical Sciences, Australia). The critical role of lipid digestion and structuring on drug delivery using milk and milk- like systems. 9:30-9h45 Camille Dumont (Claude Bernard Lyon University, Villeurbannne, France). Solid lipid nanocarriers for oral delivery of peptides. 9:45-10:00 10 :00-10:30 Keynote : Sébastien Lecommandoux (Bordeaux University, France). Lipid and polymer based vesicles : from biomimetic membranes towards smart drug delivery systems. 10 :30 Coffee break – Posters Session 4 – Lipids and nutrition / Lipids and nutraceutic Chairmen: Rob Winwood (DSM Nutritional Products Europe Ltd, Switzerland), Xavier Collet (INSERM, Toulouse, France). 10:45-10:50 Frédéric Fine (SFEL, PARIS, France). The French Society for the Study of Lipids (SFEL) 10:50-11:20 Keynote : Philip Calder(University of Southampton, UK). Omega-3 fatty acids and inflammation : From membrane to nucleus and from bench to beside. 11:20-11:35 Claire Mayer (Le Mans University, Laval, France). Microalgae rich in omega-3 fatty acids as preventive food supplements against metabolic syndrome and obesity: comparative effects of Phaeodactylum tricornutum and Tisochrysis lutea. 11:35-11h50 Abida Benahmed Djilali (Mouloud Mammeeri University, Tizi-Ouzou, Algeria) Anamyclus Clavatus leaves as traditional diet to prevent elevation of lipid serum level and gastric inflammation. 11:50-12:05 Aracely CháveZ-Piña (Instituto Politécnico Nacional, Ciudad de México, Mexico) Anti-inflammatory effect and gastric safety of the combination of docosahexaenoic acid and naproxen in rats. 12:05-12h30 Posters 12:30 – Lunch 13:30 – 14:30 – Posters Tuesday, October 1st, 2019 – Afternoon session Session 4 – Lipids and nutrition / Lipids and nutraceutic Chairmen Frédéric Fine (SFEL President), Tim Wooster (Nestlé RC, Switzerland) 14:30-15:00 Keynote : Rob Winwood (DSM Nutritional Products Europe Ltd, Switzerland). LCPs in infant formula : the critical importance of the ARA:DHA balance. 15:00-15:15 Kristina Audiejaityte (Wageningen University, the Netherlands). The effect of partly replacing vegetable fat with bovine milk fat in infant formula on postprandial lipid metabolism: a proof-of-principle study in healthy young male adults. 15:15-15:30 Marie-Caroline Michalski (INRA, INSERM, Lyon University, France). Circulating sphingolipid profile is modified by exogenous intake of sphingolipids via supplementation with milk polar lipids in overweight postmenopausal women. 15:30-15:45 Sylvie Demignot (EPHE, Paris, France). Impact of a short-term high fat/high fructose diet on luminal secretions by the small intestine epithelium: a breeding ground for bacterial overgrowth? 15:45-15:55 Matthieu Guillevic (VALOREX, Fougères, France). BLEU-BLANC-COEUR: health leaning agriculture. 15 :55 Coffee break – Posters Session – Prix de thèse Chairmen : Vincent Rioux (Agrocampus, Rennes, France), Hubert Schaller (CNRS, Strasbourg, France), Frédéric Fine (TERRES INOVIA, Pessac, France). 16:15-16:30 SFEL PhD award – Oscar Laguna (CIRAD, Montferrier-sur-Lez, France). Valorization of phenolic compounds in rapeseed and sunflower meals: from the dry fractionation process of the raw materials to the synthesis of multifunctional molecules. 16:30-16:45 GERLI PhD award – Marielle Margier (Aix-Marseille University, France). Intestinal absorption of vitamin D and K: molecular mechanisms and interaction with pulses compounds). 16:45-17:00 GERLI PhD award – Gaétan Drouin(Laboratory of Biochemistry and Human Nutrition, Rennes, France). Metabolism and nutritional interest of n-3 docosapentaenoic acid. From dairy lipid to direct supplementation. 17:00-17h15 GERLI PhD award – Josselin Lupette (Michigan State University, East Lansing, USA). Lipid droplets in a secondary endosymbiont: a case study of Phaeodactylum Tricornutum. 17:30 Gala Dinner and Visit (Bus) Wednesday, October 2st, 2019 – Morning session Session 4 – Lipids and nutrition / Lipids and nutraceutic Chairmen : Delplanque Bernadette (Paris-Sud University, Orsay France), Larbi Rhazi (UniLaSalle, Beauvais, France). 9h30-10:00 Keynote : Sophie Layé (NutriNeuro, Université de Bordeaux, France). Relevance of nutritional omega-3 fatty acids for depression and anxiety. 10:15-10:30 Benoît Chénais (Le Mans Université, Laval, France). Preventive effects of lipid extracts from P. tricornutum microalga in a cellular model of non-alcoholic fatty liver disease. 10 :30-10 :45 Apolline Goudmaeker (Louvain Institute of Biomolecular Science and Technology, Louvain Belgium). A significant supplementation in fish oil does not rectify an induced omega-3 fatty acids deficiency in juvenile zebrafish, highlighting the importance of a regular intake of omega-3 fatty acids. 10:45 Coffee break – Posters Session 5 – Hot topics and prospective researches Chairmen : Magali Deleu (Gembloux Agro-Bio Tech, Liège, Belgique), Eric Gontier (Université de Picardie Jules Verne, Amiens). 11:00-11:30 Keynote : Alexandrine During (Université de Lille, France). Osteoporosis a role for lipids. 11:30-11h45 Adrian Troncoso Ponce (Génie Enzymatique et Cellulaire, UTC, Compiègne, France). Lipid metabolism and circadian clock in Arabidopsis thaliana. 11:45-11h55 Pierre Bernard-Savary (CHROMACIM, La Sure en Chartreuse, France). Why an