Anti-MFGE8 (full length) polyclonal antibody (DPABH-07389) This product is for research use only and is not intended for diagnostic use. PRODUCT INFORMATION Antigen Description Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor- independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication.Medin is the main constituent of aortic medial amyloid. Immunogen Recombinant full length protein corresponding to amino acids 1-387 of Human Human Milk Fat Globule 1 (NP_005919.1) Isotype IgG Source/Host Rabbit Species Reactivity Human Purification Protein A purified Conjugate Unconjugated Applications WB Format Liquid Size 100 μg Buffer pH: 7.20; Constituent: 100% PBS Preservative None Storage Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles. GENE INFORMATION 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved Gene Name MFGE8 milk fat globule-EGF factor 9 protein [ Homo sapiens ] Official Symbol MFGE8 Synonyms MFGE8; milk fat globule-EGF factor 8 protein; BA46; HMFG; MFGM; SED1; hP47; EDIL1; MFG- E8; SPAG10; OAcGD3S; HsT19888; lactadherin; medin; sperm surface protein hP47; sperm associated antigen 10; breast epithelial antigen BA46; O-acetyl disialoganglioside synthase; Entrez Gene ID 4240 Protein Refseq NP_001108086.1 UniProt ID Q08431 Pathway Amyloids; Integrins in angiogenesis; Function integrin binding; phosphatidylethanolamine binding; phosphatidylserine binding; 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved.