10/6/17 FOR EXTERNAL USE KEY MESSAGES – ZIKA VIRUS DISEASE Purpose: This document is for internal and external use. The document contains cleared key messages for use in developing other materials. Information in this document is current as of October 6, 2017. No further updates will be provided. For the latest information on Zika, please visit www.cdc.gov/Zika. Updated information is in blue. CONTENTS Background on Zika...................................................................................................................................................................... 2 Outbreak Summary ...................................................................................................................................................................... 3 Symptoms .................................................................................................................................................................................... 3 Transmission ................................................................................................................................................................................ 3 Mosquito (Vector) Transmission ............................................................................................................................................. 4 Mosquitoes and Hurricanes ................................................................................................................................................. 6 Periconceptional/Intrauterine/Perinatal transmission ........................................................................................................... 6 Sexual Transmission ................................................................................................................................................................ 7 Blood Transfusion .................................................................................................................................................................... 8 Breastfeeding .......................................................................................................................................................................... 8 Testing & Diagnosis ...................................................................................................................................................................... 8 Treatment .................................................................................................................................................................................... 9 Prevention ................................................................................................................................................................................... 9 Preventing Mosquito Transmission of Zika Virus .................................................................................................................. 10 Insect Repellent ................................................................................................................................................................. 10 Mosquito Control at Home ................................................................................................................................................ 11 Mosquito Control during an Outbreak .............................................................................................................................. 12 Integrated Mosquito Control ............................................................................................................................................. 12 Mosquito Surveillance and Control Methods and Tools.................................................................................................... 12 Preventing Sexual Transmission ............................................................................................................................................ 15 Preventing Zika Infection in Pregnancy ................................................................................................................................. 16 Recommendations for Couples Interested in Conceiving .................................................................................................. 17 Preventing Unintended Pregnancy during the Zika Virus Outbreak ..................................................................................... 18 Zika Virus Blood & Tissue Safety ........................................................................................................................................... 19 Puerto Rico Survey of Blood Collection Centers ................................................................................................................ 19 Health Effects Associated with Zika ........................................................................................................................................... 20 1 10/6/17 FOR EXTERNAL USE Microcephaly ......................................................................................................................................................................... 21 Diagnosis of Microcephaly ................................................................................................................................................. 21 Pyriproxyfen ....................................................................................................................................................................... 22 Guillain-Barré Syndrome ............................................................................................................................................................ 22 Zika & the United States ............................................................................................................................................................ 22 Zika Pregnancy Registries ...................................................................................................................................................... 23 National Reporting: Pregnant Women & outcomes ............................................................................................................. 23 Zika & US Territories .................................................................................................................................................................. 25 Zika & Colombia ......................................................................................................................................................................... 26 international Travel Recommendations .................................................................................................................................... 27 International and Overseas US Territory Travel Notices ....................................................................................................... 28 Domestic Travel Guidance (applies to continental United States and Hawaii) ..................................................................... 28 CDC Guidance & Recommendations for Healthcare Providers ................................................................................................. 29 Obstetrical Healthcare Providers .......................................................................................................................................... 29 Prenatal Diagnosis of Congenital Zika Virus Infection ....................................................................................................... 30 Pediatric Healthcare Providers .............................................................................................................................................. 32 Birth Defects ...................................................................................................................................................................... 32 Potential Outcomes & Prognosis ....................................................................................................................................... 33 Clinical Guidance ................................................................................................................................................................ 33 Infection Control ................................................................................................................................................................... 35 Laboratory Testing ..................................................................................................................................................................... 35 Types of Tests ........................................................................................................................................................................ 36 Testing for Non-Pregnant Women and Men ......................................................................................................................... 37 Testing for Pregnant Women ................................................................................................................................................ 37 Testing for Congenital Zika Virus Infection ............................................................................................................................ 38 Pathology Testing .................................................................................................................................................................. 39 What CDC