Quarterly Review of Literature 1st & 2nd Quarter 2016 Table of Contents Long QT Syndrome (LQTS) ...................................................................................................................................... 2 Acquired Long QT Syndrome ................................................................................................................................ 10 BRS – Brugada Syndrome (BrS) ............................................................................................................................. 15 Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) ........................................................................ 25 Channelopathies ................................................................................................................................................... 27 Wolff-Parkinson-White Syndrome (WPW) ........................................................................................................... 29 Arrhythmia ............................................................................................................................................................ 30 Implantable Cardioverter Defibrillator (ICD) ........................................................................................................ 33 Wearable Cardioverter Defibrillator ..................................................................................................................... 39 Sudden Cardiac Arrest (SCA) ................................................................................................................................. 39 Sudden Cardiac Death (SCD) ................................................................................................................................. 39 Screening ............................................................................................................................................................... 49 CPR ........................................................................................................................................................................ 51 Automated External Defibrillator (AED) ............................................................................................................... 53 Sudden Unexpected Death in Children (SUDC) .................................................................................................... 54 Hypertrophic Cardiomyopathy (HCM) .................................................................................................................. 55 Dilated Cardiomyopathy (DCM) ............................................................................................................................ 59 Cardiomyopathy .................................................................................................................................................... 64 Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) ................................................................................ 66 Arrhythmogenic Right Ventricular Dysplasia (ARVD) ........................................................................................... 66 Timothy’s Syndrome (TS) ...................................................................................................................................... 69 Andersen Tawil Syndrome .................................................................................................................................... 69 Short QT (SQT) ...................................................................................................................................................... 70 Barth Syndrome .................................................................................................................................................... 71 Neurological .......................................................................................................................................................... 71 Sudden Unexpected Death in Epilepsy (SUDEP) ................................................................................................... 71 Epilepsy ................................................................................................................................................................. 71 Miscellaneous ....................................................................................................................................................... 72 SADS Quarterly Research Literature Review 2016 – Q1&2. Page 1 Quarterly Review of Literature 1st & 2nd Quarter 2016 Long QT Syndrome (LQTS) Left thoracic sympathectomy in a premature infant with long QT syndrome and heart failure. Surendran S, Kumar TK, Knott-Craig CJ. Cardiol Young. 2016 Jun 20:1-3. [Epub ahead of print] PMID: 27322872 [PubMed - as supplied by publisher] Similar articles Febrile temperature facilitates herg/i<sub>kr</sub> degradation through an altered k<sup>+</sup> dependence. Zhao Y, Wang T, Guo J, Yang T, Li W, Koichopolos J, Lamothe SM, Kang Y, Ma A, Zhang S. Heart Rhythm. 2016 Jun 16. pii: S1547-5271(16)30437-4. doi: 10.1016/j.hrthm.2016.06.019. [Epub ahead of print] PMID: 27321242 [PubMed - as supplied by publisher] Similar articles Long QT Syndrome and Potentially Pathogenic Genetic Variants--In Reply. Van Driest SL, Wells QS, Roden DM. JAMA. 2016 Jun 14;315(22):2467-8. doi: 10.1001/jama.2016.2921. No abstract available. 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