Mouse anti-Bacteria Yersinia Ruckeri Monoclonal antibody, clone 8G6/G7 (DMAB6804) This product is for research use only and is not intended for diagnostic use. PRODUCT INFORMATION Product Overview Mouse anti-bacteria yersinia ruckeri monoclonal antibody. Yersinia Ruckeri IgG fraction obtained by immunizing mice with five Chilean isolates of Yersinia ruckeri (whole bacterial cells). The IgG fraction was purified using Protein G-Sepharose. Antigen Description Y. ruckeri is a Gram-negative, rod-shaped bacterium that shows a variable motility due to the presence of flagella. These flagella are not always observed. It is the causative agent of enteric redmouth disease (ERM) which is characterized by a chronic or acute enterosepticemia with high morbidity and mortality rates in salmonids and non-salmonids species. Six serovars have been described according to whole-cell serological typing. Isotype IgG2b Source/Host Mouse Clone 8G6/G7 Conjugate Unconjugated Applications ELISA, WB, IF Stability Stable at least one year at -20oC. Avoid repeated freezing and thawing. Format Solution at 1.0 mg/ml in PBS. Size 100 μg Preservative None Storage Store at -20ºC. BACKGROUND Introduction Yersinia is a genus of bacteria in the family Enterobacteriaceae. Yersinia are Gram-negative rod shaped bacteria, a few micrometers long and fractions of a micrometer in diameter, and are facultative anaerobes. Some members of Yersinia are pathogenic in humans; in particular, Y. 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved pestis is the causative agent of the plague. Rodents are the natural reservoirs of Yersinia; less frequently other mammals serve as the host. Infection may occur either through blood (in the case of Y. pestis) or in an alimentary fashion, occasionally via consumption of food products (especially vegetables, milk-derived products and meat) contaminated with infected urine or feces. Speculations exist as to whether or not certain Yersinia can also be spread via protozoonotic mechanisms, since Yersinia are known to be facultative intracellular parasites; studies and discussions of the possibility of amoeba-vectored (through the cyst form of the protozoan) Yersinia propagation and proliferation are now in progress. Keywords Bacteria; Proteobacteria; GammaProteobacteria; Y. ruckeri ; Enterobacteriales; Enterobacteriaceae; Yersinia; Y. pestis; Yersinia ruckeri 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved.