Always at the cutting edge Department of Medicine 2019 Annual Report Acknowledgments The Department of Medicine would like to extend gratitude to the many people who contributed to this report, including Department leadership, Division Chiefs, administrators, and faculty members. We also thank Gigi Korzenowski and Jerry Clark of Korzenowski Design, and Kallie Gregg and Sophie Afdhal of the Department of Medicine. Much of the photography and photo research for this report were conducted by BIDMC’s James Derek Dwyer and Danielle Duffey. Jane Hayward, Lindsay Oslund, Heather Derocher, and Ann Plasso all provided expert copy editing and design consultation. We also thank the Communications and Marketing Department. Last but not least, we wish to thank all of the individuals featured in these pages for their collaboration and for all they do for the Department of Medicine, our patients, and the medical center. Table of Contents Acknowledgments ............................................................2 Leading Minds: Education at Harvard Medical School ................................................24 From the Chair ...................................................................4 Early Investigator, Timely Advances: Departmental Organization .........................................4 Sol Schulman, MD, PhD ..................................................28 From the CAO ....................................................................5 Exceptional Mentorship and Career Development, Supporting New Leadership ................................................................9 Cutting-Edge Research ..................................................30 Vice Chair Updates ...........................................................8 Cutting-Edge Conversations .........................................34 Breaking Ground on a Cutting-Edge Medical Education Leadership ....................................36 New Inpatient Building ...................................................12 Selected Publications ......................................................37 Coming Together as a New System ............................14 Research Funding: A Pioneer of Perception: Academic Year 2018-2019 ..............................................44 Mark Andermann, PhD ...................................................16 In Memoriam .....................................................................45 Awards & Honors ..............................................................18 Clinical Volume at the Cutting Edge ...........................20 Taking Bedside Rounds Anywhere and Everywhere ................................................................22 This report is interactive. Navigate using the Table of Contents above and the links throughout the report. 2 / BIDMC Department of Medicine 2019 Annual Report BIDMC Department of Medicine 2019 Annual Report / 3 Departmental Organization As of 2020 From the Chair Administration Clinical Divisions Research Divisions From the CAO Since coming together as part of Beth Israel Lahey Health As I write this message, we are completing a several month Mark Zeidel, MD ALLERGY AND INFLAMMATION HEMATOLOGY AND CLINICAL INFORMATICS last year (for more information, visit page 14), the Department journey through the first—and we hope the only—crisis phase Department Chair HEMATOLOGIC MALIGNANCIES Peter Weller, MD Yuri Quintana, PhD of Medicine has been proud to be an integral part of the new of the COVID-19 pandemic. The report in your hands describes David Avigan, MD Kevin Maguire, MS Division Chief Division Chief system as we continue to emphasize our mission: providing the achievements of one of America’s premier Departments of Division Chief Chief Administrative Officer Amanda Yano-Litwin, MHA extraordinary care to our patients, training the next generation Medicine prior to the onset of the COVID-19 epidemic. CLINICAL NUTRITION Mark Aronson, MD Division Administrator Christine VanDeWege, MA of physicians and scientists, and engaging in groundbreaking Bruce Bistrian, MD, PhD, MPH During this past academic year, the Department continued Vice Chair, Quality Division Administrator research across all of our Divisions. its tradition of providing superb, high quality care to ever- CARDIOVASCULAR MEDICINE Division Chief Donald Cutlip, MD INFECTIOUS DISEASES It has been an incredibly eventful beginning for our new system, increasing numbers of outpatients and inpatients, both on Robert Gerszten, MD Vice Chair, Clinical Care EXPERIMENTAL MEDICINE and I could not be more proud of how BILH and the Department BIDMC’s main campus and at an ever-growing number Division Chief Peter Weller, MD of Medicine has responded to the many challenges we faced and of community health centers. We continued to expand our in the Community Division Chief Jerome Groopman, MD John DiGiorgio, MPS-HHS continue to face. structural heart and congestive heart failure programs, we Grace Huang, MD Division Chief Division Administrator Amanda Yano-Litwin, MHA enhanced our interdepartmental collaborative efforts in Vice Chair, Career Throughout the entire coronavirus pandemic, from our early Division Administrator HEMOSTASIS AND THROMBOSIS transplantation, and we continued to expand our innovative Development and Mentoring ENDOCRINOLOGY, preparedness plans and managing the surge in Massachusetts, approaches towards immunotherapy in cancer care. At the DIABETES AND METABOLISM MEDICAL ONCOLOGY Robert Flaumenhaft, MD, PhD to recovering and beginning to adapt to a ‘new normal,’ the Barbara Kahn, MD Division Chief Department acted quickly, effectively, and collaboratively to care same time, we continued the planning for our new inpatient Vice Chair, Research Strategy Evan Rosen, MD, PhD David F. McDermott, MD building and we have accelerated our collaborative clinical Division Chief Division Chief for our patients and for one another during unprecedented times. Eileen Reynolds, MD IMMUNOLOGY efforts throughout the Beth Israel Lahey Health network. Every member of our Department contributed to managing Vice Chair, Education Amanda Yano-Litwin, MHA Christine VanDeWege, MA Cornelius Terhorst, PhD Our educators led the way in developing new curricula at this crisis: the Vaccine and Virology lab is at the forefront of the Division Administrator Division Administrator Division Chief Harvard Medical School and continued to recruit and train C. Christopher Smith, MD race to develop a vaccine, faculty provided surge coverage superb classes of interns, residents, and fellows. Again, our Associate Vice Chair, GASTROENTEROLOGY NEPHROLOGY INTERDISCIPLINARY MEDICINE for inpatient COVID-19 floors, staff converted clinical spaces to Education educators were honored repeatedly for their dedication, Nezam Afdhal, MD Martin Pollak, MD AND BIOTECHNOLOGY accommodate additional patients on ventilators, and residents ingenuity, and effectiveness. developed a program to donate iPads to connect loved ones with Anjala Tess, MD Division Chief Division Chief Ary Goldberger, MD isolated patients. These are just a few examples, among many, Our researchers continued to break new ground in cancer, Associate Vice Chair, Division Chief Sara Montanari Kerry Falvey that demonstrate the versatility, talent, and commitment we have vaccine development, rheumatologic, metabolic, renal, Education Division Administrator Division Administrator within the Department and at BIDMC. and cardiac diseases, and we continued to strengthen Peter Weller, MD SIGNAL TRANSDUCTION our mentoring of young investigators and junior faculty Vice Chair, Research GENERAL MEDICINE PULMONARY, CRITICAL Alex Toker, PhD It’s been a year of ups and downs met by change and innovation, members of all types. We welcomed Gyongyi Szabo, BIDMC’s CARE AND SLEEP MEDICINE and I’m eager to see what the coming months bring for the Tim McDermott, MHA Eileen Reynolds, MD Division Chief new Chief Academic Officer, to our Department. As a truly Richard Schwartzstein, MD Department of Medicine, BIDMC, and Beth Israel Lahey Health. Executive Director, Finance Division Chief outstanding Hepatologist and liver investigator, Dr. Szabo will Division Chief TRANSLATIONAL RESEARCH I hope you are as well. and Business Operations Blair Bisher, MHA AND TECHNOLOGY INNOVATION collaborate with Dr. Afdhal and colleagues in the Division of Renee Wheeler Paul Hart Miller Division Administrator Gastroenterology, Hepatology and Nutrition to further develop a Division Administrator Steven Freedman, MD, PhD comprehensive liver research program of international stature. Director, Business GERONTOLOGY Division Chief and Network Development RHEUMATOLOGY AND Although this Annual Report describes the year’s events prior Lewis Lipsitz, MD CENTER FOR VIROLOGY Scot Sternberg, MS CLINICAL IMMUNOLOGY to the pandemic, reflecting on the past year from this new Division Chief AND VACCINE RESEARCH Kevin Maguire, MS, perspective renews the pride we have in our missions and our Director, Quality Improvement George Tsokos, MD Chief Administrative Officer, Kerry Falvey confidence that these missions will endure and flourish, no Division Chief Dan Barouch, MD, PhD Department of Medicine Division Administrator Division Chief matter what challenges the pandemic has in store. Patricia Harris Division Administrator Mark L. Zeidel, MD Chair, Department of Medicine 4 / BIDMC Department of Medicine 2019 Annual Report BIDMC Department of Medicine 2019 Annual Report / 5 New Leadership in many clinical innovations in the potent induction of anti- role, Dr. McDermott will serve