SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 (SARS-COV-2) WHAT EXCTLY DID HAPPEN IN CHINA AND WHAT WAS THE WORLD HEALTH ORGANIZATION’S INVOLVMENT IN ALLOWING THIS TO BECOME A GLOBAL PANEMIC TIMELINE This extensive timeline incorporates numerous other time lines and additional research. It focuses on what exactly happened in China and in regards to the World Health Organization and how the handling of this virus got botched so badly and by who and how this eventually affected this US (and other countries). 13 Sep 20 A study done in April 2020 at the University of Cambridge estimates that the virus first emerged somewhere between 13 Sep 19 and 7 Dec 19. The scientists cautioned though that their estimate as to when the outbreak started may be wrong. Their work out assumes a constant mutation rate, which is admittedly unlikely to be the case, and the time estimate could therefore be wrong. But it is the best assumption the scientists can make at the moment, pending analysis of further patient samples stored in hospitals during 2019. The scientists created a genome network using over 1000 genomes in an attempt to map the virus’ genetic history to patient zero. So far they found three distinct but related variants of the bug more prevalent in different parts of the world. Type A of the coronavirus is believed to be the original human virus genome and the closest to the type of Covid-19 in bats. It has been found in Chinese and American patients but it’s not China’s most common variant. Until January 17 almost all isolates in Wuhan were Type B. The scientists suggest there was a “founder event” for Type B in Wuhan. However 500 miles away in the Guandong province seven of 11 samples found in patients were found to be a variant of Type A, casting doubt on the origin of the outbreak. People in China, Britain in Europe have most been affected by Type B which was the most common type in Wuhan/Hubei circulating in December. The researchers stated that Type C mutated from an offshoot or ‘daughter’ of Type B and spread to Europe, Australia, South Korea and Singapore. It was found in Hong Kong but did not appear to infect mainland China. It is thought that Covid-19 is in a constant process of evolution to overpower people’s immune systems in different parts of the world. (Type A prevalence: China, US, Chile, Spain, and Australia. Type B prevalence: China, Canada, Brazil, Denmark, UK, Belgium, France, Finland, Germany and Japan. Type C prevalence: Hong Kong, Italy and Singapore. https://metro.co.uk/2020/04/18/coronavirus-may-started-september-scientists-say-12576961/https://www.newsweek.com/coronavirus- outbreak-september-not-wuhan-1498566 17 Nov 19 Based on government date observed by South China Morning Post a 55 year old from the Hubei province appears to have been the first known person to contract Covid-19 on Nov 17. The person was not connected to the Wuhan wet-market. (In November there were 9 cases,four men and five women ages 39 - 79.) From that day onward on five new cases were reported each day. By December the total of infections stood at 27. By December 20 the total number of confirmed cases had reached 60. Two major population expansions occurred on December 8 and January 6.The Wuhan wet-market boosted Covid-19 circulation and spread it to the whole city in early December.South China Morning Post 13 Mar 2020 The WHO was warned in December about the Coronavirus, Taiwan Say. The Organization Ignored the Warning) 30 Nov 2019 Wuhan Institute of Virology scientists including Shi LiZheng published a study “Discovery of a rich gene pool of bat SARS-related coronaviruses provides new insights into the origin of SARS coronavirus” that found the following: Increasing evidence has been gathered to support the bat origin of SARS coronavirus (SARS-CoV) in the past decade. However, none of the currently known bat SARSr-CoVs is thought to be the direct ancestor of SARS-CoV. Herein, we report the identification of a diverse group of bat SARSr-CoVs in a single cave in Yunnan, China. Importantly, all of the building blocks of SARS-CoV genome, including the highly variable S gene, ORF8 and ORF3, could be found in the genomes of different SARSr-CoV strains from this single location. Based on the analysis of full-length genome sequences of the newly identified bat SARSr-CoVs, we speculate that the direct ancestor of SARS-CoV may have arisen from sequential recombination events between the precursors of these bat SARSr-CoVs prior to spillover to an intermediate host. In addition, we found bat SARSr-CoV strains with different S proteins that can all use the receptor of SARS-CoV in humans (ACE2) for cell entry, suggesting diverse SARSr-CoVs capable of direct transmission to humans are circulating in bats in this cave. Our current study therefore offers a clearer picture on the evolutionary origin of SARS-CoV and highlights the risk of future emergence of SARS-like diseases.https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1006698 In December 2019, the Hubei Province Integrated Traditional Chinese and Western Medicine Hospital, the Wuhan Central Hospital Houhu Hospital area, and the Wuhan Red Cross Hospital successively admitted some patients with pneumonia from an unknown cause. https://www.chinalawtranslate.com/en/li-wenliang-report/ 8 Dec 19 First known case of coronavirus showed symptoms according to a study by Chinese health authorities and the WHO. Subsequent research, following analysis of genome data, found that it is possible that the virus began spreading persons to person as early as 17November (not related to the Wuhan wetmarket).Express 28 Mar 2020 Coronavirus UK: Virus did NOT originate in Wuhan seafood market,claims study 9 Dec 19, Dr. Li Wenliang rotated from working in the eye clinic to the ophthalmology ward at the Wuhan Central Hospital. On January 6, 2020, Dr. Li Wenliang received an 82-year-old eye patient. The patient developed fever on January 7, was then confirmed to be infected with the novel coronavirus, and died of the illness on January 23. On January 10, Dr. Li Wenliang began to have a fever and sought care in the Wuhan Central Hospital fever clinic.https://www.chinalawtranslate.com/en/li-wenliang-report/ 16 Dec 19 Patient admitted to Wuhan Central Hospital with infection in both lungs but resistant to anti-flu drugs.https://www.axios.com/timeline-the-early-days-of-chinas-coronavirus-outbreak-and-cover-up-ee65211a-afb6-4641- 97b8-353718a5faab.html 16 Dec 19 Dr. Ai Fen, the first known whistle-blower, told People magazine in a subsequent interview that tests showed that a patient at Wuhan Central Hospital was diagnosed on December 16 as having contracted an unknown coronavirus.Previous reports said that although doctors in the city collected samples from suspected cases in late December, they could not confirm their findings because they were bogged down by bureaucracy, such as having to get approval from the Chinese Centre for Disease Control and Prevention, which could take days. South China Morning Post 13 Mar 2020 Coronavirus: China’s first confirmed Covid-19 case traced back to November 17 18 Dec 19 A 65 year old deliveryman was admitted to the Central Hospital of Wuhan with pneumonia with his condition deteriorating quickly.straitstimes.com/asia/east-asia/how-early-signs-of-the- coronavirus-were-spotted-spread-and-throttled-in-china 24 Dec 19 Doctors took fluid samples from the lungs of the 65years old deliveryman and sent them to Vision Medicals for testing according to Dr. Zhao Su, head of respiratory medicine at the hospital. straitstimes.com/asia/east-asia/how-early-signs-of-the-coronavirus-were-spotted-spread-and-throttled-in-china Interviews by the South China Morning Post with medical doctors in China suggest that Chinese doctors only realized that they were dealing with a new disease in late December.South China Morning Post 13 Mar 2020 The WHO was warned in December about the Coronavirus by Taiwan. The WHO ignored the Warning 27 Dec 19 in an unusual move Vision Medicals did not send back the test results but instead called the doctor “They just called us and said it was a new coronavirus” according to Dr. Zhao. (In late February 2020 Vision Medical confirmed the tests took place in a post it published on social media. The post said the company was involved in early studies on the new coronavirus and contributed to an article on the English version of the Chinese Medical Journal about its discovery. This article makes specific mention of a sample collected on Dec 24 from a 65 years old patient. (In another post on 28 Jan a person who did not say where he was working but only gave the area – Huangpu, Guangzhou where Vision Medicals is located – posted that they noticed a close similarity with the SARS coronavirus in test results of a sample collected on Dec 24, but decided to study the results more closely before returning them, due to their significance. The company did however share the data with the Chinese Academy of Medical Sciences). On Dec 27 the lab had sequenced most of the virus genome and had confirmed it was a coronavirus similar to the SARS virus. In the following days company executives paid a visit to Wuhan to discuss their findings with local hospital officials and disease control authorities. “There was an intensive and confidential investigation under way, and officials from the hospital and disease control centre had acknowledgedthat there were many similar patients”.