Final Program TARGETING CANCER: Technology Biology ASTRO’SO’S 556TH6 ANNUAL MEETING Meeting Dates: September 14 -17, 2014 • Exhibit Dates: September 14 -16, 2014 • Moscone Center • San Francisco Download ASTROmobile – the offi cial meeting app. See page 22 for details. www.astro.org/annualmeeting #ASTRO14 Final Program TARGETING CANCER: Technology Biology ASTRO’SR O ’ S 556TH6 ANNUAL MEETING Meeting Dates: September 14 -17, 2014 • Exhibit Dates: September 14 -16, 2014 • Moscone Center • San Francisco Download ASTROmobile cial – the offi meeting app. See page 22 for details. www.astro.org/annualmeeting HELD IN CONJUNCTION WITH: #ASTRO14 AMERICAN SOCIETY OF RADIOLOGIC TECHNOLOGISTS (ASRT) ASSOCIATION OF RESIDENTS IN RADIATION ONCOLOGY (ARRO) SOCIETY FOR RADIATION ONCOLOGY ADMINISTRATORSHeld in (SROA) conjunction with: American Society of Radiologic Technologists (ASRT) Association of Residents in Radiation Oncology (ARRO) Society for Radiation Oncology#ASTRO13 Administrators (SROA) Welcome TO THE 56TH ANNUAL MEETING OF THE AMERICAN SOCIETY FOR RADIATION ONCOLOGY “Targeting Cancer: Technology and Biology” Dear Colleagues, It is my honor to welcome you to the vibrant city of San Francisco and ASTRO’s 56th Annual Meeting. We are confi dent that the meeting will provide ample opportunity for professional networking, exchange of new ideas and knowledge in clinical, basic and translational research as we continue our mission to move the fi eld of radiation oncology forward and improve the quality of life for the patients we serve. The theme of this year’s meeting is “Targeting Cancer: Technology and Biology.” The Annual Meeting Scientifi c Program Committee, led by Lynn D. Wilson, MD, MPH, FASTRO, along with a dedicated group of volunteers, has assembled an inspiring and exciting program from a record-breaking number of abstract submissions. Novel developments in biology and cutting-edge technology will be highlighted in a broad spectrum of educational sessions, panel discussions, oral presentations, poster presentations and digital posters. The popular Plenary Session and Clinical Trials Session will both be unopposed to allow the entire membership to attend these highly rated and important sessions. The meeting offi cially begins with the Presidential Symposium, “Local-regional Management of Breast Cancer: A Changing Paradigm. ”Moderated by Jay R. Harris, MD, FASTRO, and Thomas A. Buchholz, MD, FASTRO, the symposium will highlight recent practice-changing landmark studies and current developments in the local-regional management of breast cancer. Our keynote speakers, Hedvig Hricak, MD, PhD, Frank McCormick, PhD, FRS, and Sidney Dekker, PhD, MA, MSc, will address a range of topics, including oncologic imaging, biology and targeting in oncology, and human error and safety concerns (see page 45 for more details). I invite you to join me in congratulating our 2014 ASTRO Gold Medalists, Fellows and Honorary Member during the Awards Ceremony on Tuesday at 10:15 a.m. in the Esplanade Ballroom. I also extend a very warm welcome and note of appreciation to our industry colleagues for their support and contributions to our specialty. I encourage you to visit the Exhibit Hall to learn about their latest developments. I hope the Annual Meeting will provide you with new insights, ideas and inspiration to bring back to your practice and your patients. Enjoy the meeting and all that San Francisco has to off er. Bruce G. Haff ty, MD, FASTRO President, ASTRO Chair, Annual Meeting Steering Committee 2 ASTRO 2014 / 56TH ANNUAL MEETING Table of Contents WELCOME TO THE 56TH ANNUAL MEETING 2 Board of Directors 4 Continuing Medical Education 5 Annual Meeting Committee Members 8 Abstract Reviewers 10 Session Reviewers 12 Gold Medal Recipients 13 Fellow Recipients 14 Honorary Member Recipient 15 Annual Meeting Abstract Awards 16 GENERAL INFORMATION 19 ASTROmobile 22 Concessions 24 Industry-Expert Theater 26 Industry Satellite Symposia 27 Posters 29 Shuttle Service 31 Moscone Center Floor Plans 34 SCHEDULE OF EVENTS eContouring Learning Lab 41 Live Self-Assessment CME Sessions (SA-CME) 42 Presidential Symposium 44 Keynote Speakers 45 Meeting Highlights 47 ARRO Program 48 Young Physicians’ Workshop 51 Nurses’ Program 52 International Program 54 APEx 57 RO-ILS: Radiation Oncology Incident Learning System 58 Schedule by Day Saturday 61 Sunday 63 Monday 75 Tuesday 88 Wednesday 103 POSTER PRESENTATIONS 123 INDEXES By Author 185 By Topic 194 EXHIBITOR LISTINGS Exhibitor List 207 Exhibitor List by Product/Service Category 215 Exhibit Hall Floor Plan 218 Board of Directors 2014 Offi cers and Board of Directors Colleen A.F. Lawton, MD, FASTRO, Chair Bruce G. Haff ty, MD, FASTRO, President Bruce D. Minsky, MD, President-elect Phillip M. Devlin, MD, FASTRO, Secretary/Treasurer Jeff Michalski, MD, MBA, FASTRO, Secretary/ Treasurer-elect Michael L. Steinberg, MD, FASTRO, Immediate Past Chair Council Chairs and Vice-chairs Carol H. Hahn, MD, Clinical Aff airs and Quality Council Chair Lawrence Marks, MD, FASTRO, Clinical Aff airs and Quality Council Vice-chair Laura A. Dawson, MD, Education Council Chair Paul M. Harari, MD, FASTRO, Education Council Vice-chair Bharat B. Mittal, MD, FASTRO, Government Relations Council Chair Geraldine M. Jacobson, MD, MBA, MPH, FASTRO Government Relations Council Vice-chair Brian Kavanagh, MD, Health Policy Council Chair Thomas J. Eichler, MD, FASTRO, Health Policy Vice-chair Mary K. Martel, PhD, FASTRO, Science Council Chair Theodore L. DeWeese, MD, Science Council Vice-chair Laura I. Thevenot, Chief Executive Offi cer 4 ASTRO 2014 / 56TH ANNUAL MEETING Continuing Medical Education NEEDS STATEMENT responsibilities. Program content has been designed Cancer is a leading cause of death worldwide. to address specifi c documented and clinically According to the World Health Organization (WHO), important practice gaps in physician knowledge and cancer deaths worldwide are projected to continue competence. We will continue to emphasize quality to rise to more than 11 million in 2030. The American and safety issues in the delivery of radiation therapy Cancer Society estimates that in 2014 1.6 million new in the areas of treatment techniques, equipment, cases of cancer will be diagnosed. Nearly two-thirds terminology and professional responsibilities. of these patients will receive radiation therapy during their illness – most with the intent to cure the Upon completion of this live activity, attendees should cancer. Advances in the applications, technologies be able to do the following: and methodologies of radiation oncology continue 1. Examine the advances in technology and biology to evolve rapidly and the delivery of radiation therapy that help improve patient outcomes and quality has become more complex, making it imperative that of life. the radiation oncology professional remain current in 2. Determine the value of combining novel the state-of-the-art techniques. The American Society strategies in technology and biology to radiation for Radiation Oncology is committed to providing therapy in the treatment of cancer. educational programming that creates a forum for 3. Employ quality and safety measures in the global collaboration on issues in radiation oncology delivery of radiation therapy. to improve professional practice by increasing level of knowledge, as required to improve competency in ELEMENTS OF COMPETENCE the fi eld of oncology. The Annual Meeting program has been designed to narrow the competency gaps of patient/ PROGRAM DESCRIPTION AND OBJECTIVES patient-centered care, medical knowledge, The scientifi c program will continue to be the ideal practice-based learning and improvement, platform to bring together clinicians, scientists and interpersonal skills and communication, researchers from all of the oncologic disciplines to professionalism, work in interdisciplinary teams, exchange ideas, promote multidisciplinary care and evidence-based practice, quality improvement, address the educational and professional utilization of informatics, professional standing and development interests of our attendees. Scientifi c and commitment to lifelong learning, 12 of the 15 core educational sessions will cover specifi c clinical areas competencies embraced by the American Board of including breast, central nervous system, Medical Specialties, the Accreditation Council for gastrointestinal, genitourinary, gynecological, head Graduate Medical Education and the Institute of and neck, lymphoma, musculoskeletal, pediatric, Medicine. sarcoma and thoracic cancers. Radiation biology and radiation physics concepts will also be explored. TARGET AUDIENCE During the 2014 Annual Meeting, we will highlight The Annual Meeting program is intended for all science that showcases how technology and biology health professionals in the fi eld of oncology, with advance the fi eld and improve patient outcomes and particular emphasis on radiation oncologists, quality of life. Signifi cant advances in both radiation oncology residents, radiation biologists, technology and biology continue to move our fi eld radiation physicists, medical dosimetrists, radiation forward, improving our ability to target cancer therapists, radiation oncology nurses, medical through both technologic and biologic approaches. oncologists, oncological surgeons and pathologists. At this year’s meeting, we will bring together the latest developments in basic, translational, applied CONTINUING MEDICAL EDUCATION technology and clinical sciences as they relate to our multidisciplinary