INTERNATIONAL NANOTOXICOLOGY CONGRESS nano June 1-4, 2016 BOSTON, USA 8TH INTERNTIONAL NANOTOXICOLOGY CONGRESS Table of Contents Welcome from the chairs ............................................................................................................................. 2 Committees.................................................................................................................................................... 3 A welcome message from the Sustainable Nanotechnology Organization .............................................. 5 Program at a glance...................................................................................................................................... 6 Detailed daily program ...............................................................................................................................10 Thursday, June 2, 2016 ............................................................................................................................... 11 The nanotechnology legal and regulatory landscape plenary .............................................................. 11 Parallel Sessions 1 through 6 ............................................................................................................... 12 Dosimetry Workshop ............................................................................................................................ 18 Young investigators colloquium ...........................................................................................................20 Friday, June 3, 2016 .................................................................................................................................. 22 Biomedical applications for nanotechnology: from discovery to clinical trials of polymeric nanoparticles plenary ........................................................................................................................... 22 Parallel Sessions 7 through 12 ............................................................................................................. 24 Nanoceria: Benefits and risks workshop .............................................................................................30 Saturday June 4, 2016 ................................................................................................................................ 33 Nanoscience approaches to heterogeneity in biological systems plenary ........................................... 33 Parallel Sessions 13 through 15 ........................................................................................................... 34 Abstracts: Poster presentation:.....................................................................................................................................37 Group 1 (1 - 100) Thursday, June 2, 2016 ................................................................................................. 37 Group 2 (101 - 283) Friday, June 3, 2016 ................................................................................................ 136 Oral presentations: ....................................................................................................................................320 List of exhibitor: ........................................................................................................................................416 List of sponsors: .........................................................................................................................................417 Sponsors for poster awards: .....................................................................................................................418 8TH INTERNTIONAL NANOTOXICOLOGY CONGRESS Welcome from the chairs On behalf of the International Advisory Board and Local Organizing Committee, we are pleased to welcome you to the 2016 International Nanotoxicology Congress, and Boston, Massachusetts, USA. This conference is the 8th in a continuing series of international meetings that are broadly focused on nanotoxicology, one that began in Boston in 2006. Thus, it is fitting that we return to this beautiful and historic city for our 10th year anniversary meeting. The objective of this conference is to bring together scientists from academia, industry, government agencies, and non-governmental organizations to present current research findings, focus their respective talents and expertise, and initiate new collaborations in an effort to ensure the safe implementation of nanotechnology. The Advisory Board has been working hard over the past two years to develop the scientific program for this conference, and includes plenary lectures, symposia, workshops, poster sessions, and dedicated time for presentations by young scientists. We would like to specifically recognize two organizations that have provided support, without which the 2016 conference would not have been possible. An early gift from the Turkish Society of Toxicology following the 2014 conference covered initial logistical costs. In addition, we are very grateful to the Sustainable Nanotechnology Organization (SNO) for providing the administrative and legal structures and assisting the Chairs in putting on an event of this size. Last but not least, we would like to thank our sponsors and exhibitors for their support. We are looking forward to interacting with all of you during the Conference and wishing you all a productive and enjoyable Conference. Alison Elder, Co-Chair Philip Demokritou, Co-Chair 8TH INTERNTIONAL NANOTOXICOLOGY CONGRESS Committees Teresa Fernandes, Heriot-Watt Univ. Terry Gordon, NYU Local Organizing Committee: Mary Gulumian, Univ. Witwatersrand Dhimiter Bello, Univ. Mass., Lowell Sabina Halappanavar, Health Canada James Bonner, NCSU Andrij Holian, Univ. Montana Jared Brown, Univ. of Colorado Saber Hussain, WPAFB Erdem Coskun, NIST/Gazi Univ. Valerian Kagan, Univ. Pittsburgh Philip Demokritou, Harvard Univ. (co-chair) Ali Esat Karakaya, Gazi Univ. Alison Elder, Univ. Rochester (co-chair) Harald Krug, EMPA Andrij Holian, Univ. Montana Andrew Maynard, Univ. of Michigan Saber Hussain, WPAFB Nancy Monteiro-Riviere, KSU Srikanth Nadadur, NIEHS Srikanth Nadadur, NIEHS Timothy Nurkiewicz, WV Univ. Andre Nel, UCLA Dale Porter, NIOSH Timothy Nurkiewicz, WV Univ. Christie Sayes, Baylor Univ. Dale Porter, NIOSH Anna Shvedova, NIOSH Nora Savage, NSF Mark Wiesner, Duke Univ. Kai Savolainen, TTL Christie Sayes, Baylor Univ. International Advisory Board: Anna Shvedova, NIOSH Anders Baun, DTU Vicki Stone, Heriot-Watt Univ. Dhimiter Bello, Univ. Mass., Lowell Justin Teeguarden, PNNL James Bonner, NCSU Treye Thomas, CPSC Sara Brenner, CNSE Shuji Tsuruoka, Shinshu Univ. Jared Brown, Univ. of Colorado Lang Tran, IOM Flemming Cassee, RIVM Håkan Wallin, NRCWE Chunying Chen, NanoCenter China Mark Wiesner, Duke Univ. Hongda Chen, USDA Il Je Yu, Hoseo Univ. Erdem Coskun, NIST/Gazi Univ. Yuliang Zhao, Chinese Acad. Sci. Kenneth Dawson, CBNI, UCD Philip Demokritou, Harvard Univ. Alison Elder, Univ. Rochester Ayse Basak Engin, Gazi Univ. Bengt Fadeel, Karolinska Inst. 3 8TH INTERNTIONAL NANOTOXICOLOGY CONGRESS Abstract Review Committee: Terry Gordon, New York University. Andrij Holian, University of Montana Sabina Halappanavar, Health Canada, Canada (Chair) Dhimiter Bello, University of Massachusetts, Lowell. Nancy Monteiro-Riviere, Kansas State University. Sara Brenner, CNSE, USA Christie Sayes, Baylor University, USA Flemming Cassee, RIVM, Netherlands Vicki Stone, Heriot-Watt University, UK Chunying Chen, NanoCenter, P.R. China Shuji Tsuruoka, Shinshu University, Japan Ayse Basak Engin, Gazi University, Turkey Robert Yokel, University of Kentucky. 4 8TH INTERNTIONAL NANOTOXICOLOGY CONGRESS A welcome message from the Sustainable Nanotechnology Organization The Sustainable Nanotechnology Organization (SNO) welcomes you to the 2016 International Nanotoxicology Congress to Boston, Massachusetts, and we are pleased to partner with this conference. We would also like to introduce you to SNO and encourage you to become members. SNO is a non-profit, worldwide professional society that is unique in its mission of focusing on a very new technology and its relationship to sustainability. No other organization has this combination of science and values. SNO is comprised of individuals and institutions that are engaged in: • Research and development of sustainable nanotechnology • Implications of nanotechnology for Environment, Health, and Safety • Advances in nanoscience, methods, protocols and metrology • Education and understanding of sustainable nanotechnology • Applications of nanotechnology for sustainability As a professional society, SNO provides forum to advance knowledge in all aspects of sustainable nanotechnology, including both applications and implications. SNO has partnered with the Royal Society of Chemistry(RSC) to offer our members publication opportunities in Environmental Science: Nano. In addition, RSC supports a SNO/RSC award for Emerging Investigators. The SNO annual conference is a place where the new community of sustainable nanotechnology is being formed and advanced. The conference program is built around providing excellent talks with plenty of time for interdisciplinary networking and social interactions. SNO’s Newsletter (SNO Report) provides readers with an excellent platform to discuss both the benefits and risks of nanotechnology. The SNO meeting is small enough to provide meaningful discussions and a neutral ground with both