20th Transcription Assembly Meeting 2018 25th-27th July 2018 Centre for DNA Fingerprinting and Diagnostics, Hyderabad Conference Program DAY 1 - 25th July 8:45 - 9:15 Arrival and registration 9:15 - 9:25 Debashis Mitra (Director, CDFD) Inauguration and Welcome address 9:25 - 13:15 Moderator: Deepti Jain (RCB, Delhi) 9:25 - 10:50 Dipankar Chatterjee (IISc, Bangalore) " Comprehensive Analysis of two Iron Storage Proteins: A case study with Dps and Ferritin" 9:50 - 10:15 Gowrishankar J(CDFD, Hyderabad) “Antisense transcripts that generate toxic R-loops in E. coli are themselves Rendered undetectable because of the R-loops so formed” 10:15 - 10:40 Jayanta Mukhopadhyay (Bose Institute, Kolkata) " Direct evidence of robustness in a two-component system 10.40 - 11.05 Vikas Jain (IISER, Bhopal) “Dissection of the factors responsible for the stability and activity of T4 latepromoter transcription effector gp45” 11:05 - 11:25 Tea 11:25 - 11:50 Dipak Dutta (IMTech, Chandigarh) " Rho is a potential regulator of trace metal homeostasis in Escherichia coli" 11:50 – 12:15 Deepti Jain (RCB, Delhi) “Transcription Regulation of flagellar gene network in Pseudomonas Aeruginosa” 12:15 –12:40 Harinarayanan(CDFD, Hyderabad) “SpoT and GppA hydrolases prevent the activation of RelA by pppGppin Escherichia coli” 12:40 –13:05 Jitender Thakur (JNU, Delhi) “KIX domain containing Mediator subunit Med15 is important for transcriptional regulation of seed development in rice” 13:05- 14:00 Lunch 14:00 - 15:00 Poster session 15:00 - 15:20 Tea 15:20 - 18:30 Moderator: Sharmila Sengupta (NIBMG, West Bengal) 15:20 - 15:45 Sanjeev Khosla(CDFD, Hyderabad) “Role of mycobacterial epigenetic regulators inreprogramming of host transcriptionalmachinery during infection” Kumar Somasundaram ((IISc, Bangalore) 15:45 - 16:10 "Essential nature of mRNA N6-methyladenosine modification for the sustenance of transcript abundance of actively transcribed genes” Saumitra Das (IISc, Bangalore) 16:10 - 16:35 “miRNA mediated regulation of p53 and its isoform ∆40p53: Consequences on cellular gene expression” 16:35 - 17:00 Sreedhar Chinnaswamy(NIBGM, Kalyani) “Expression of human interferon lambda 3 and 4 and impact on diseases” 17:00 - 17:15 Tea 17:15 - 17:40 Purnima Bhargava (CCMB, Hyderabad) “Yeast PAF1 complex restricts the accumulation of RNA polymerase III and counters the replication stress on the transcribed genes” 17:40 - 18:05 Himanshu Sinha(TIFR, Mumbai) “Functional heterogeneity in ribosomal proteins mediates phenotypic variation" Rakesh Mishra (CCMB, Hyderabad) 18:05 - 18:30 “Structural basis of transcriptional memory during mitosis” 7:30 - 9:30 Dinner (BANQUET) DAY 2 - 26th July 9:15 -11:20 Moderator: Sudha Bhattacharya (JNU, Delhi) 9:15 - 9:40 Tapas Kundu(JNCASR, Bangalore) “A Natural Compound Derived Small molecule Activator of Master Epigenetic Enzyme, p300/CPB: Implications in Neural Disorders and Therapeutics” 9:40- 10:05 Debabrata Biswas(IICB, Kolkata) “Dynamic regulation of transcription by p300- mediated site-specific acetylation of human AF4 during xenotoxic stress response”. 10:05 - 10:30 Ullas Kolthur(TIFR, Mumbai) “De-acetylation and Epigenomic regulation” 10:30 - 10:55 Sanjeev Das (NII, Delhi) “Deciphering the regulatory milieu of tumor suppressor sirtuin 6” 10.55 - 11.20 Devyani Haldar (CDFD, Hyderabad) “mTORC2 controls glycolytic gene expression by regulating sirtuins” 11:20 - 11:40 Tea 11:40 - 12:05 Gopal Kundu (NCCS, Pune) “Notch1 Transcriptionally Regulates CD133 expression and activates MAPK activation in CD133+ Cancer Stem Cells that leads to Melanoma Growth and Lung Metastasis” 12:05 – 12:30 K Natarajan(JNU, New Delhi) “In Black and White: Transcriptional Regulatory Networks Linked to Melanogenesis Uncovered by Chemo-genomic Profiling” 12:30 – 12:55 Shyamal K Goswami(JNU, New Delhi) “Benevolent ROS mediated Gene Regulation in Failing Heart” 13:00 - 14:00 Lunch 14:00 - 15:00 Poster session 15:00 - 15:30 Tea 15:30- 19:15 Moderator: Rohini Muthuswamy (JNU, Delhi) 15:30 - 15:55 Shravanti Rampalli(InStem, Bangalore) “Distinct fibroblasts lineages are defined by global methyl marks” 15:55 - 16:20 Sanjay Gupta (ACTREC, Mumbai) “Histone H3 variant H3.3 deficiency affects global epi-genomic landscape and enhances the progression of hepatocellular carcinoma” Kundan Sengupta(IISER, Pune) 16:20 - 16:45 “Nup93 sub-complex modulates expression and spatial organization of the HOXA gene locus in the interphase nucleus” Shweta Tyagi (CDFD, Hyderabad) 16:45 - 17:10 “MLL regulates transcription of non-coding RNA in repeat regions”. 17:10 - 17:30 Tea 17:30 - 17:55 Sharmila Sengupta(NIBMG,Kalyani) “Cervical cancer subtypes harbouring integrated and/ or episomal HPV16 portray distinct molecular phenotypes based on transcriptome profiling of mRNAs and miRNAs” 17:55 - 18:20 Chandrima Das (SINP, Kolkata) “PML-NB protein Sp110 promotes HBV persistence through modulation of Type-I Interferon Response Pathway” 18:20 - 18:45 Uday kumar Ranga(JNCASR, Bangalore) “The emerging promoter-variant strains of HIV-1C in India and transcriptional silence” 18:45 - 19:10 Samit Chattopadhyay(IICB, Kolkata) “Metabolism in cancer cells: An advantage to proliferation and Metastasis” 19:30 - 21:00 Dinner DAY 3 - 27th July 9:15 -12:30 Moderator: Shravanti Rampalli(InStem, Bangalore) 9:15 – 9.40 Sanjeev Galande (IISER, Pune) " Regulation of transcription factor SP1 by β-catenin destruction complex modulates Wnt response" 9:40- 10:05 Sudha Bhattacharya (JNU, Delhi) " EhRrp6, a 3’-5’exoribonuclease, is an RNA quality control factor essential for Entamoeba histolytica growth and erythrophagocytosis" Shantanu Chowdhury(IGIB, Delhi) 10:05- 10:30 “Non-duplex DNA structures emerge as molecular anchors ofEpigenetic modifications” 10:30- 10:45 Mukund Ramakrishnan(IISER, Behrampur) “Control of Clock Gene Expression through Facultative Heterochromatin” 10:45- 11:05 Tea 11: 05 - 11:30 Rohini Muthuswamy (JNU, Delhi) "Regulation of ATM and ATR by SMARCAL1 and BRG1” 11:30- 11:55 Murali Bashyam (CDFD, Hyderabad) “An alternative and non-canonical oncogenic role for cytoplasm-localized ARID1B in pancreatic cancer” 11:55 – 12:20 Susanta Roy Choudhury (SGCC & RI, Kolkata) “Insights into the transcriptional function of gain-of- 12:20 – 12:30 function mutant p53” Dipankar Chatterjee(Concluding remarks) 12:30 - 13:30 Lunch .