INTERNATIONAL SOCIETY FOR HEART AND LUNG TRANSPLANTATION FINAL PROGRAM PRAHA,CZECH REPUBLIC PrPRAGUEague CONGRESS CENTRE 32nd Annual Meeting & Scientific Sessions April 18-21, 2012 INTERNATIONAL SOCIETY FOR HEART AND LUNG TRANSPLANTATION FINAL PROGRAM 32nd Annual Meeting & Scientific Sessions April 18-21, 2012 TABLE OF CONTENTS: About ISHLT 2 Board of Directors 4 Scientific Program Committee 6 Abstract Reviewers 7 Committees 15 Scientific Councils 19 Past Presidents 22 Award Recipients 24 Daily Schedule Foldouts between 24-37 Corporate Partners 30 Continuing Medical Education 32 Scientific Session Highlights 36 Meeting Rooms Floor Plan 50 INSIDE FRONT COVER ISHLT Academy Progam 53 FOR POSTIION ONLY Program At a Glance 64 Scientific Program 80 List of Exhibiting Companies 228 Exhibit Hall and Poster Floor Plan 230 Exhibitors 232 ABOUT ISHLT The International Society for Heart and Lung Transplan- tation (ISHLT) is a not-for-profit, multidisciplinary, professional organization dedicated to improving the care of patients with advanced heart or lung disease through transplantation, mechanical support and innovative thera- pies via research, education and advocacy. ISHLT was created in 1981 at a small gathering of about 15 cardiologists and cardiac surgeons. Today we have over THE PURPOSES OF THE SOCIETY ARE: 2700 members from over 45 countries, representing over 1. To associate persons interested in the fields 15 different professional disciplines involved in the man- of heart and lung transplantation, end-stage agement and treatment of end-stage heart and lung dis- heart and lung disease, and related sciences. ease. This multinational, multidisciplinary mix is one of 2. To encourage and stimulate basic and the biggest strengths of the Society. It brings greater breadth clinical research in these disciplines and to and depth to our educational offerings and provides an promote new therapeutic strategies. exceptional environment for networking and exchanging 3. To hold scientific meetings featuring information on an informal basis. presentations and discussions relevant to these disciplines. Our members include anesthesiologists, basic scientists, cardiologists, cardiothoracic surgeons, ethicists, immunol- 4. To sponsor a scientific journal for the ogists, nurses, pathologists, perfusionists, pharmacists, publication of manuscripts related to these disciplines. pulmonologists, tissue engineers, transplant coordinators and infectious disease specialists. Despite their differing 5. To establish and maintain an international specializations, all ISHLT members share a common dedi- registry for heart and lung transplantation. cation to the advancement of the science and treatment of 6. To award research grants and establish end-stage heart and lung disease. endowments for the study of these disciplines. 2 3 2011-2012 BOARD OF DIRECTORS OFFICERS EX OFFICIO BOARD MEMBERS Lori J. West, MD, DPhil, President Mandeep R. Mehra, MD, Editor-in-Chief, University of Alberta, Edmonton, Alberta, Canada Journal of Heart and Lung Transplantation Brigham & Women’s Hospital, Boston, MA, USA David O. Taylor, MD, President-Elect Cleveland Clinic, Cleveland, OH, USA Marshall I. Hertz, MD, Thoracic Transplant Registry Medical Director John Dark, MB, FRCS, Past President University of Minnesota, Minneapolis, MN, USA Freeman Hospital, Newcastle upon Tyne, United Kingdom Stuart C. Sweet, MD, PhD, Duane Davis, MD, Secretary-Treasurer 2012 Scientific Program Chair Duke University Medical Center, Durham, NC, USA St. Louis Children’s Hospital, St. Louis, MO, USA Heather J. Ross, MD, MHSc, FRCP(c), Development Committee Chair DIRECTORS Toronto General Hospital, Toronto, CANADA, Raymond L. Benza, MD Allegheny General Hospital, Pittsburgh, PA, USA Amanda W. Rowe, ISHLT Executive Director Susan M. Chernenko, RN, MN, NP Toronto General Hospital, Toronto, Ontario, Canada Maria G. Crespo-Leiro, MD Hospital Universitario A Caruna, La Coruna, Spain STAFF James F. George, PhD University of Alabama at Birmingham, Amanda W. Rowe Birmingham, AL, USA Executive Director Allan R. Glanville, MBBS, MD, FRACP Phyllis Glenn St. Vincent’s Hospital, Sydney, Sustralia Director of Membership Services Richard Kirk, MA FRACP, FRCPCH Lisa A. Edwards Freeman Hospital, Newcastle upon Tyne, Director of Meetings United Kingdom Lee Ann Mills Patricia A. Uber, PharmD Director of Operations University of Maryland, Baltimore, MD, USA Susie Newton J. David Vega, MD Communications Manager Emory Clinic, Atlanta, GA, USA Webmaster Geert M. Verleden, MD, PhD University Hospital Gasthuisberg, Germany Florian M. Wagner, MD University Heart Center Hamburg, Hamburg, Germany George M. Wieselthaler, MD University of California San Francisco, CA, USA 14673 Midway Road, Suite 200 Addison, TX75001 Phone: 972-490-9495 Fax: 972-490-9499 www.ishlt.org 4 5 ANNUAL MEETING SCIENTIFIC ABSTRACT REVIEWERS PROGRAM COMMITTEE Clemens Aigner, MD, Medical University of Vienna, Vienna, Austria Arezu Z. Aliabadi, MD, Medical University of Vienna, Vienna, Austria PROGRAM CHAIR: Claus B. Andersen, MD, D.M.Sci, Rigshospitalet, Copenhagen, Stuart C. Sweet, MD, PhD, St. Louis, MO, USA Denmark PRESIDENT: Annalisa Angelini, MD, University of Padua, Padova, Italy Lori J. West, MD, DPhil, Edmonton, Alberta, Canada Samantha J. Anthony, PhD, MSW, Hospital for Sick Children/ McMaster University, Toronto, ON, Canada Allan R. Glanville, MD, FRACP, Sydney, Australia Christopher J. Arendt, PharmD, RPh, Mayo Clinic, Carla C. Baan, MD, Rotterdam, The Netherlands Rochester, MN, USA Agnes M. Azimzadeh, PhD, University of Maryland, Mark L. Barr, MD, Los Angeles, CA, USA Baltimore, MD, USA Gerald J. Berry, MD, Stanford, CA, USA Aditya Bansal, MD, Ochsner Clinic Foundation, Stephen C. Clark, MD, Newcastle Upon Tyne, United Kingdom New Orleans, LA, USA David A. Baran, MD, FACC, Newark Beth Israel Medical Center, Lara Danziger-Isakov, MD, MPH, Cleveland, OH, USA Newark, NJ, USA Marc De Perrot, MD, Toronto, ON, Canada Christian Benden, MD, St. Vincent’s Hospital, Sydney, Australia Marion Delcroix, MD, Leuven, Belgium Elizabeth Clark Benedetti, PharmD, Baptist Memorial Hospital, Memphis, TN, USA Annette J. DeVito Dabbs, RN, PhD, Pittsburgh, PA, USA Raymond L. Benza, MD, Allegheny General Hospital, Stephan M. Ensminger, MD, PhD, Erlangen, Germany Pittsburgh, PA, USA Melanie D. Everitt, MD, Salt Lake City, UT, USA Sangeeta Bhorade, MD, University of Chicago Medical Center, Chicago, IL, USA Reda Girgis, MB, BCh, Baltimore, MD, USA Eliane Billaud, PhD, APHP, Universite Paris Descartes-Hopital Daniel R. Goldstein, MD, New Haven, CT, USA European Georges Pompidou, Paris, France Cynthia J. Gries, MD, MSc, Pittsburgh, PA, USA Filio Billia, MD, PhD, FRCPC, University Health Network, Toronto, ON, Canada Richard Kirk, MA FRCP FRCPCH, Emma Birks, MD, PhD, FRCP, University of Louisville/Jewish Newcastle Upon Tyne, United Kingdom Hospital, Louisville, KY, USA Lorriana E. Leard, MD, San Francisco, CA, USA Arie Blitz, MD, University Hospitals Case Medical Center, Deborah J. Levine, MD, San Antonio, TX, USA Cleveland, OH, USA Annette Boehler, MD, University Hospital Zurich, Zurich, Bronwyn J. Levvey, RN, Grad Dip, Melbourne, Australia Switzerland Joren C. Madsen, MD, DPhil, Boston, MA, USA Michael Bowdish, MD, University of Southern California Keck Kenneth R. McCurry, MD, Cleveland, OH, USA School of Medicine, Los Angeles, CA, USA Patrick Bruneval, MD, Universite Paris Descartes-Hopital Mandeep R. Mehra, MD, MBBS, FACC, FACP, Baltimore, MD, USA European Georges Pompidou, Paris, France Soon J. Park, MD, Rochester, MN, USA Marie M. Budev, DO, MPH, The Cleveland Clinic, Cleveland, Richard N. Pierson, III, MD, Baltimore, MD, USA OH, USA Clare L. Burdett, MBBS, MRCS, Freeman Hospital, Newcastle Evgenij V. Potapov, MD, PhD, Berlin, Germany upon Tyne, United Kingdom Luciano Potena, MD, PhD, Bologna, Italy Margaret M. Burke, FRCPath, Royal Brompton and Harefield Eulalia Roig, MD, Barcelona, Spain NHS Foundation Trust, Middlesex, United Kingdom Charles E. Canter, MD, St. Louis Children’s Hospital, St. Louis, Heather J. Ross, MD, MHSc, FRCP(c), Toronto, ON, Canada MO, USA Josef Stehlik, MD, PhD, Salt Lake City, UT, USA Javier Carbone, MD, PhD, Gregorio Maranon Hospital, Madrid, Spain Lynne W. Stevenson, MD, Boston, MA, USA Michael P. Carboni, MD, Duke University Medical Center/Duke David O. Taylor, MD, Cleveland, OH, USA Children’s Hospital, Durham, NC, USA Dirk Van Raemdonck, MD, PhD, Leuven, Belgium Joern Carlsen, MD, PhD, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark Erik A. M. Verschuuren, MD, PhD, Groningen, The Netherlands Marilia Cascalho, MD, PhD, University of Michigan, Ann Arbor, Glen P. Westall, FRACP, PhD, Melbourne, Australia MI, USA 6 7 Murali Chakinala, MD, Washington University School of Medicine, Peter M. Eckman, MD, University of Minnesota, Minneapolis, St. Louis, MO, USA MN, USA Daniel C. Chambers, MBBS, MRCP, FRACP, MD, The Prince Jeffrey D. Edelman, MD, University of Washington, Seattle, WA, USA Charles Hospital, Brisbane, Queensland, Australia Thomas M. Egan, MD, University of North Carolina, Durham, Susan Chambers, MSN, CRNP, University of Pennsylvania, USA NC, USA Kevin M. Chan, MD, University of Michigan, Ann Arbor, MI, USA Howard J. Eisen, MD, Drexel University College of Medicine and Cecilia Chaparro, MD, Toronto General Hospital, Toronto, Hahnemann University Hospital, Philadelphia, PA, USA ON, Canada Christopher R. Ensor, PharmD, BCPS-CV, The Johns Hopkins Susan M. Chernenko, RN, MN, NP, Toronto General Hospital, Hospital, Baltimore,