PDGFB Split FISH Probe Storage Instruction: Store at 4°C in the dark. Entrez GeneID: 5155 Catalog Number: FS0009 Gene Symbol: PDGFB Regulatory Status: For research use only (RUO) Gene Alias: FLJ12858, PDGF2, SIS, SSV, c-sis Product Description: Labeled FISH probes for identification of gene split using Fluoresecent In Situ Gene Summary: The protein encoded by this gene is a Hybridization Technique. (Technology) member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for Probe 1: cells of mesenchymal origin and are characterized by a Size: motif of eight cysteines. This gene product can exist Fluorophore: either as a homodimer (PDGF-BB) or as a heterodimer Location: PDGFB(Texas Red) with the platelet-derived growth factor alpha polypeptide Approximately 470kb (PDGF-AB), where the dimers are connected by Texas Red disulfide bonds. Mutations in this gene are associated 22q13.1 with meningioma. Reciprocal translocations between Probe 2: chromosomes 22 and 7, at sites where this gene and Size: that for COL1A1 are located, are associated with a Fluorophore: particular type of skin tumor called dermatofibrosarcoma Location: PDGFB(FITC) protuberans resulting from unregulated expression of Approximately 610kb growth factor. Two alternatively spliced transcript FITC variants encoding different isoforms have been identified 22q13.1 for this gene. [provided by RefSeq] Probe Gap: The gap between two probes is approximately 50 kb Source: Genomic DNA Origin: Human Notice: We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections. Applications: FISH-Ce, FISH-P (See our web site product page for detailed applications information) Protocols: See our web site at http://www.abnova.com/support/protocols.asp or product page for detailed protocols Form: Liquid Supplied Product: DAPI Counterstain (1500 ng/mL ) 125 uL for each 100 uL FISH Probe Page 1/1 Powered by TCPDF (www.tcpdf.org).