The World Journal of Biological Psychiatry ISSN: 1562-2975 (Print) 1814-1412 (Online) Journal homepage: http://www.tandfonline.com/loi/iwbp20 Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry Piotr Lewczuk, Peter Riederer, Sid E. O’Bryant, Marcel M. Verbeek, Bruno Dubois, Pieter Jelle Visser, Kurt A. Jellinger, Sebastiaan Engelborghs, Alfredo Ramirez, Lucilla Parnetti, Clifford R. Jack Jr, Charlotte E. Teunissen, Harald Hampel, Alberto Lleó, Frank Jessen, Lidia Glodzik, Mony J. de Leon, Anne M. Fagan, José Luis Molinuevo, Willemijn J. Jansen, Bengt Winblad, Leslie M. Shaw, Ulf Andreasson, Markus Otto, Brit Mollenhauer, Jens Wiltfang, Martin R. Turner, Inga Zerr, Ron Handels, Alexander G. Thompson, Gunilla Johansson, Natalia Ermann, John Q. Trojanowski, Ilker Karaca, Holger Wagner, Patrick Oeckl, Linda van Waalwijk van Doorn, Maria Bjerke, Dimitrios Kapogiannis, H. Bea Kuiperij, Lucia Farotti, Yi Li, Brian A. Gordon, Stéphane Epelbaum, Stephanie J. B. Vos, Catharina J. M. Klijn, William E. Van Nostrand, Carolina Minguillon, Matthias Schmitz, Carla Gallo, Andrea Lopez Mato, Florence Thibaut, Simone Lista, Daniel Alcolea, Henrik Zetterberg, Kaj Blennow, Johannes Kornhuber & on Behalf of the Members of the WFSBP Task Force Working on this Topic: Peter Riederer, Carla Gallo, Dimitrios Kapogiannis, Andrea Lopez Mato, Florence Thibaut To cite this article: Piotr Lewczuk, Peter Riederer, Sid E. O’Bryant, Marcel M. Verbeek, Bruno Dubois, Pieter Jelle Visser, Kurt A. Jellinger, Sebastiaan Engelborghs, Alfredo Ramirez, Lucilla Parnetti, Clifford R. Jack Jr, Charlotte E. Teunissen, Harald Hampel, Alberto Lleó, Frank Jessen, Lidia Glodzik, Mony J. de Leon, Anne M. Fagan, José Luis Molinuevo, Willemijn J. Jansen, Bengt Winblad, Leslie M. Shaw, Ulf Andreasson, Markus Otto, Brit Mollenhauer, Jens Wiltfang, Martin R. Turner, Inga Zerr, Ron Handels, Alexander G. Thompson, Gunilla Johansson, Natalia Ermann, John Q. Trojanowski, Ilker Karaca, Holger Wagner, Patrick Oeckl, Linda van Waalwijk van Doorn, Maria Bjerke, Dimitrios Kapogiannis, H. Bea Kuiperij, Lucia Farotti, Yi Li, Brian A. Gordon, Stéphane Epelbaum, Stephanie J. B. Vos, Catharina J. M. Klijn, William E. Van Nostrand, Carolina Minguillon, Matthias Schmitz, Carla Gallo, Andrea Lopez Mato, Florence Thibaut, Simone Lista, Daniel Alcolea, Henrik Zetterberg, Kaj Blennow, Johannes Kornhuber & on Behalf of the Members of the WFSBP Task Force Working on this Topic: Peter Riederer, Carla Gallo, Dimitrios Kapogiannis, Andrea Lopez Mato, Florence Thibaut (2017): Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry, The World Journal of Biological Psychiatry, DOI: 10.1080/15622975.2017.1375556 To link to this article: http://dx.doi.org/10.1080/15622975.2017.1375556 © 2017 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. Published online: 27 Oct 2017. Submit your article to this journal Article views: 435 View related articles View Crossmark data Downloaded by [the Medical University of Vienna], [Professor Siegfried Kasper] at 06:38 03 November 2017 Full Terms & Conditions of access and use can be found at http://www.tandfonline.com/action/journalInformation?journalCode=iwbp20 Download by: [the Medical University of Vienna], [Professor Siegfried Kasper] Date: 03 November 2017, At: 06:38 THE WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY, 2017 https://doi.org/10.1080/15622975.2017.1375556 WFSBP CONSENSUS PAPER Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry Piotr Lewczuka,b , Peter Riedererc, Sid E. O’Bryantd, Marcel M. Verbeeke,f , Bruno Duboisg, Pieter Jelle Visserh,i, Kurt A. Jellingerj, Sebastiaan Engelborghsk,l, Alfredo Ramirezm,n,o , Lucilla Parnettip , Clifford R. Jack Jrq , Charlotte E. Teunissenr, Harald Hampels, Alberto Lleot,u , Frank Jesseno,v, Lidia Glodzikw, Mony J. de Leonw, Anne M. Faganx,y, Jose Luis Molinuevoz,aa, Willemijn J. Jansenh, Bengt Winbladab, Leslie M. Shawac, Ulf Andreassonad,ae, Markus Ottoaf, Brit Mollenhauerag, Jens Wiltfangah,ai,aj, Martin R. Turnerak, Inga Zerrai,al, Ron Handelsh,ab , Alexander G. Thompsonak , Gunilla Johanssonab, Natalia Ermanna, John Q. Trojanowskiac , Ilker Karacam, Holger Wagnerm, Patrick Oecklaf, Linda van Waalwijk van Doorne,f, Maria Bjerkek, Dimitrios Kapogiannisam, H. Bea Kuiperije,f, Lucia Farottip,YiLiw, Brian A. Gordonx,an , Stephane Epelbaumg, Stephanie J. B. Vosh, Catharina J. M. Klijne, William E. Van Nostrandao, Carolina Minguillonz, Matthias Schmitzai,al, Carla Galloap, Andrea Lopez Matoaq, Florence Thibautar , Simone Listas, Daniel Alcoleat,u , Henrik Zetterbergad,ae,as, Kaj Blennowad and Johannes Kornhubera , on Behalf of the Members of the WFSBP Task Force Working on this Topic: Peter Riederer, Carla Gallo, Dimitrios Kapogiannis, Andrea Lopez Mato, Florence Thibaut aDepartment of Psychiatry and Psychotherapy, Universit€atsklinikum Erlangen, and Friedrich-Alexander Universit€at Erlangen-Nurnberg,€ Erlangen, Germany; bDepartment of Neurodegeneration Diagnostics, Medical University of Białystok, and Department of Biochemical Diagnostics, University Hospital of Białystok, Białystok, Poland; cCenter of Mental Health, Clinic and Policlinic of Psychiatry, Psychosomatics and Psychotherapy, University Hospital Wurzburg,€ Wurzburg,€ Germany; dInstitute for Healthy Aging, University of North Texas Health Science Center, Fort Worth, TX, USA; eDepartment of Neurology, Radboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour, Radboud Alzheimer Center, Nijmegen, The Netherlands; fDepartment of Laboratory Medicine, Radboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour, Radboud Alzheimer center, Nijmegen, The Netherlands; gInstitut de la Memoire et de la Maladie d’Alzheimer (IM2A), Salp^etrierie Hospital, INSERM UMR-S 975 (ICM), Paris 6 University, Paris, France; hDepartment of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Alzheimer Center Limburg, Maastricht University, Maastricht, The Netherlands; iDepartment of Neurology, Alzheimer Centre, Amsterdam Neuroscience VU University Medical Centre, Amsterdam, The Netherlands; jInstitute of Clinical Neurobiology, Vienna, Austria; kReference Center for Biological Markers of Dementia (BIODEM), University of Antwerp, Antwerp, Belgium; lDepartment of Neurology and Memory Clinic, Hospital Network Antwerp (ZNA) Middelheim and Hoge Beuken, Antwerp, Belgium; mDepartment of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany; nInstitute of Human Genetics, University of Bonn, Bonn, Germany; oDepartment of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany; pSection of Neurology, Center for Memory Disturbances, Lab of Clinical Neurochemistry, University of Perugia, Perugia, Italy; qDepartment of Radiology, Mayo Clinic, Rochester, MN, USA; rNeurochemistry Lab and Biobank, Department of Clinical Chemistry, Amsterdam Neuroscience, VU University Medical Center Amsterdam, Amsterdam, The Netherlands; sAXA Research Fund & UPMC Chair, Sorbonne Universites, Universite Pierre et Marie Curie (UPMC) Paris 06, Inserm, CNRS, Institut du Cerveau et de la Moelle Epiniere (ICM), Departement de Neurologie, Institut de la Memoire et de la Maladie d’Alzheimer (IM2A), Hopital^ Pitie-Salp^etriere, Boulevard de l’hopital,^ Paris, France; tDepartment of Neurology, Institut d’Investigacions Biomediques Sant Pau - Hospital de Sant Pau, Universitat Autonoma de Barcelona, Barcelona, Spain; uCentro de Investigacion Biomedica en Red en Enfermedades Neurodegenerativas, CIBERNED, Spain; vGerman Center for Neurodegenerative Disorders (DZNE), Bonn, Germany; wCenter for Brain Health, Department of Psychiatry, NYU Langone Medical Center, New York, NY, USA; xKnight Alzheimer’s Disease Research Center, Washington University School of Medicine, Saint Louis, MO, USA; yDepartment of Neurology, Washington University School of Medicine, Saint Louis, MO, USA; zBarcelonabeta Brain Research Center, Pasqual Maragall Foundation, Barcelona, Spain; aaAlzheimer’s Disease and Other Cognitive Disorders Unit, Hospital Clınic, Institut d’Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; abKarolinska Institutet, Department NVS, Center for Alzheimer Research, Division of Neurogeriatrics, Huddinge, Sweden; acDepartment of Pathology and Laboratory Medicine, Downloaded by [the Medical University of Vienna], [Professor Siegfried Kasper] at 06:38 03 November 2017 Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; adClinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Molndal,€ Sweden; aeInstitute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at the University of Gothenburg, Molndal,€ Sweden; afDepartment of Neurology, University of Ulm, Ulm, Germany; agParacelsus-Elena-Klinik, Kassel and University Medical Center Gottingen,€ Department of Neurology, Gottingen,€ Germany; ahDepartment of Psychiatry & Psychotherapy, University of Gottingen,€ Gottingen,€ Germany; aiGerman Center for Neurodegenerative Diseases