Table II. List of genes differentially expressed between high and low risk endometrial carcinomas Fold Change ID Symbol Entrez Gene Name Type of molecule (high vs low risk) ACSL6 ACSL6 acyl-CoA synthetase long-chain family member 6 -1,053 enzyme ACTRT2 ACTRT2 actin-related protein T2 -1,207 other ALKBH3 ALKBH3 alkB, alkylation repair homolog 3 (E. coli) 1,016 enzyme ARMC3 ARMC3 armadillo repeat containing 3 -1,250 other ARPC5 ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 1,045 other ATG4C ATG4C ATG4 autophagy related 4 homolog C (S. cerevisiae) -1,233 peptidase C14orf70 C14ORF70 chromosome 14 open reading frame 70 1,025 other C17orf78 C17ORF78 chromosome 17 open reading frame 78 -1,418 other C1orf88 C1ORF88 chromosome 1 open reading frame 88 -1,055 other C5orf34 C5ORF34 chromosome 5 open reading frame 34 -1,085 other CASC2 CASC2 cancer susceptibility candidate 2 1,021 other transcription CIAO1 CIAO1 cytosolic iron-sulfur protein assembly 1 homolog (S. cerevisiae) -1,430 regulator COG5 COG5 component of oligomeric golgi complex 5 -1,176 transporter COL17A1 COL17A1 collagen, type XVII, alpha 1 -1,196 other COX4I1 COX4I1 cytochrome c oxidase subunit IV isoform 1 -1,123 enzyme CPSF3 CPSF3 cleavage and polyadenylation specific factor 3, 73kDa -1,380 other CRYBB1 CRYBB1 crystallin, beta B1 -1,214 other DAPK3 DAPK3 death-associated protein kinase 3 -1,063 kinase G-protein coupled DARC DARC Duffy blood group, chemokine receptor 1,024 receptor DIDO1 DIDO1 death inducer-obliterator 1 1,027 other DNAH17 DNAH17 dynein, axonemal, heavy chain 17 -1,188 other DSCAM DSCAM Down syndrome cell adhesion molecule -1,097 other ECHDC2 ECHDC2 enoyl CoA hydratase domain containing 2 -1,190 other translation EIF4A1 EIF4A1 eukaryotic translation initiation factor 4A1 -1,155 regulator family with sequence similarity 19 (chemokine (C-C motif)-like), FAM19A5 FAM19A5 member A5 -1,450 other FBXL22 FBXL22 F-box and leucine-rich repeat protein 22 1,022 other transcription FOXQ1 FOXQ1 forkhead box Q1 -1,329 regulator GCNT3 GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 1,024 enzyme GP9 GP9 glycoprotein IX (platelet) -1,211 other G-protein coupled GPR63 GPR63 G protein-coupled receptor 63 -1,133 receptor G-protein coupled GPRC5D GPRC5D G protein-coupled receptor, family C, group 5, member D -1,113 receptor HAP1 HAP1 huntingtin-associated protein 1 1,023 other HMGB3 HMGB3 high-mobility group box 3 -1,096 other HPN HPN hepsin -1,432 peptidase HSFX1 HSFX1 heat shock transcription factor family, X linked 1 -1,087 other HYI HYI hydroxypyruvate isomerase homolog (E. coli) 1,035 enzyme KIAA1632 KIAA1632 KIAA1632 -1,125 other KIAA1919 KIAA1919 KIAA1919 1,033 other KRT6B KRT6B keratin 6B -1,132 other Q8WX68_HUMAN LOC286297 hypothetical protein LOC286297 -1,231 other Q96K35_HUMAN LOC84931 hypothetical LOC84931 1,022 other LYN LYN v-yes-1 Yamaguchi sarcoma viral related oncogene homolog -1,030 kinase MFSD3 MFSD3 major facilitator superfamily domain containing 3 -1,429 other p-value <0.001 Table II. List of genes differentially expressed between high and low risk endometrial carcinomas (continuation) Fold Change ID Symbol Entrez Gene Name Type of molecule (high vs low risk) MPP2 MPP2 membrane protein, palmitoylated 2 -1,101 kinase MRFAP1L1 MRFAP1L1 Morf4 family associated protein 1-like 1 -1,223 other APPBP1 NAE1 NEDD8 activating enzyme E1 subunit 1 1,024 enzyme NBPF14 NBPF14 neuroblastoma breakpoint family, member 14 -1,196 other NIPBL NIPBL Nipped-B homolog (Drosophila) -1,321 other transcription NKX6-2 NKX6-2 NK6 homeobox 2 -1,085 regulator transcription NPAS1 NPAS1 neuronal PAS domain protein 1 -1,228 regulator NXT2 NXT2 nuclear transport factor 2-like export factor 2 -1,114 transporter OR7A2_HUMAN OR7A2P olfactory receptor, family 7, subfamily A, member 2 pseudogene -1,168 other phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 PDE4B PDE4B dunce homolog, Drosophila) 1,031 enzyme transcription PHF12 PHF12 PHD finger protein 12 1,025 regulator PLA2G5 PLA2G5 phospholipase A2, group V -1,146 enzyme pleckstrin homology domain containing, family G (with RhoGef PLEKHG5 PLEKHG5 domain) member 5 -1,353 other Q9UHS2_HUMAN PPP1R8 protein phosphatase 1, regulatory (inhibitor) subunit 8 -1,055 phosphatase Q9P175_HUMAN PRO2268 hypothetical protein PRO2268 -1,123 other PUS7L PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like -1,156 other RAB11FIP1 RAB11FIP1 RAB11 family interacting protein 1 (class I) -1,180 other RAB11FIP3 RAB11FIP3 RAB11 family interacting protein 3 (class II) 1,024 other RAP1GDS1 RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 -1,099 other RDH10 RDH10 retinol dehydrogenase 10 (all-trans) -1,206 enzyme transcription REST REST RE1-silencing transcription factor 1,025 regulator RFC4 RFC4 replication factor C (activator 1) 4, 37kDa -1,173 other RGL1 RGL1 ral guanine nucleotide dissociation stimulator-like 1 -1,439 other RPS24 RPS24 ribosomal protein S24 1,020 other SLC4A11 SLC4A11 solute carrier family 4, sodium borate transporter, member 11 1,022 transporter SPATA2L SPATA2L spermatogenesis associated 2-like -1,451 other SPIN1 SPIN1 spindlin 1 -1,055 other transcription STAT2 STAT2 signal transducer and activator of transcription 2, 113kDa -1,091 regulator TMEM102 TMEM102 transmembrane protein 102 -1,029 other transcription TRIM25 TRIM25 tripartite motif-containing 25 -1,137 regulator USP20 USP20 ubiquitin specific peptidase 20 -1,140 peptidase transcription WT1 WT1 Wilms tumor 1 -1,545 regulator LGICZ1 ZACN zinc activated ligand-gated ion channel 1,089 ion channel ZNF790 ZNF790 zinc finger protein 790 -1,173 other p-value <0.001 .