Supplementary Data Table 1. Genes upregulated in N-Myc-overexpressing mouse Mac1+/Gr1+ BM cells Probeset C-myc / N-myc / N-myc / C- Gene Title Representative 430v2 Vector Fold Vector Fold myc Fold Public ID Change Change Change 1435368_a_at 2.3 4.6 2.1 poly (ADP-ribose) polymerase family, member 1 BB767586 1455648_at 1.3 3.0 2.1 similar to reduced expression 2 /// similar to reduced expression 2 BG244780 1438973_x_at 2.5 9.8 4.0 gap junction membrane channel protein alpha 1 BB043407 1419915_at 2.0 3.0 2.1 DNA segment, Chr 10, ERATO Doi 438, expressed AW538011 1454842_a_at 1.6 4.0 2.3 UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, AI853240 polypeptide 2 1436704_x_at 2.1 9.2 3.2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent), AV215673 methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase 1423142_a_at 2.0 2.5 2.1 GTP binding protein 4 AI987834 1420043_s_at 2.5 5.7 2.8 THO complex 1 AW107924 1439444_x_at 1.5 4.3 2.5 transmembrane emp24-like trafficking protein 10 (yeast) /// similar to AV213456 transmembrane trafficking protein 1438610_a_at 1.9 4.9 2.3 Crystallin, zeta BB793369 1434291_a_at 2.5 4.3 2.8 small EDRK-rich factor 1 AA709993 1422716_a_at 2.8 6.5 2.6 acid phosphatase 1, soluble AW554436 1447895_x_at -1.3 2.3 2.6 PAN3 polyA specific ribonuclease subunit homolog (S. cerevisiae) AV368189 1434097_at 1.5 3.2 2.5 Transcribed locus BM218328 1420982_at 1.1 3.5 2.6 RNA-binding region (RNP1, RRM) containing 2 NM_133242 1433853_at 2.6 7.5 2.6 mindbomb homolog 1 (Drosophila) BG063791 1419824_a_at 1.6 4.0 2.1 RIKEN cDNA A230062G08 gene AI875121 1453797_at 7.5 14.9 2.1 phosphatase, orphan 2 AK010147 1440803_x_at 2.3 4.0 2.3 tachykinin receptor 3 BB498416 1455737_at -2.0 1.1 2.8 RIKEN cDNA C030002B11 gene AU040848 1450954_at -1.5 2.8 4.6 YME1-like 1 (S. cerevisiae) BB826168 1439047_s_at 1.3 2.3 2.1 RecQ protein-like BB258011 1423149_at -2.1 1.5 4.3 S-phase kinase-associated protein 1A AV347477 1456864_at -1.0 3.7 4.0 --- BB210733 1447150_at -1.3 2.3 2.5 pam, highwire, rpm 1 AW107633 1455930_at -1.4 3.0 7.0 hypothetical protein LOC673503 BI651113 1423140_at -1.1 2.5 2.3 lysosomal acid lipase 1 AI596237 1440924_at -1.6 2.1 3.5 M-phase phosphoprotein 1 BM239553 1457656_s_at -1.4 2.1 2.8 RIKEN cDNA C230085N15 gene BB235011 1420115_at -1.7 2.5 4.3 exosome component 8 C80158 1437162_at -1.9 2.1 3.5 GPI-anchored membrane protein 1 BM203355 1439302_at -1.1 2.6 3.7 ubiquitin-activating enzyme E1-like 2 AV266743 1425884_at -1.6 2.5 3.2 brix domain containing 1 BC025093 1441788_s_at -1.1 2.8 3.2 cDNA sequence BC068171 BB779105 1426906_at -1.0 2.6 3.2 interferon activated gene 203 M74124 1419484_a_at -1.2 2.5 2.5 glioblastoma amplified sequence NM_008095 1425922_a_at -2.3 17.1 73.5 v-myc myelocytomatosis viral related oncogene, neuroblastoma M36277 derived (avian) 1417695_a_at -1.4 2.3 3.2 sterol O-acyltransferase 1 BG064396 1457285_at -1.3 2.5 3.0 zinc finger protein 187 BB354728 1449217_at -1.2 2.1 2.6 caspase 8 associated protein 2 NM_011997 1436584_at -1.5 2.5 4.0 sprouty homolog 2 (Drosophila) BB529691 1439638_at -1.2 2.1 2.5 Erbb2 interacting protein BB336138 1437100_x_at -1.3 2.3 3.0 proviral integration site 3 BB206220 1416886_at 1.1 2.5 3.2 nuclear DNA binding protein NM_020558 1443771_x_at -1.4 2.8 4.3 MAD homolog 7 (Drosophila) BB241324 1443966_at -1.3 2.8 4.9 3 days neonate thymus cDNA, RIKEN full-length enriched library, BF466594 clone:A630040N16 product:unclassifiable, full insert sequence 1447813_x_at -1.1 2.5 2.8 src-like adaptor AV247013 1419926_at -1.1 2.1 2.6 Thioredoxin domain containing 10 AV259382 1440822_x_at -1.2 2.1 2.5 RalBP1 associated Eps domain containing protein BB333366 1458667_at -1.3 4.3 7.5 RIKEN cDNA 4930519N13 gene AV266695 1447757_x_at 1.3 3.2 2.6 inositol polyphosphate-5-phosphatase F AV033355 1443665_at -1.4 11.3 14.9 Expressed sequence AI852444 BE994639 1440179_x_at -1.2 2.1 2.6 IBR domain containing 1 BB268139 1441391_at -1.5 3.0 4.0 Guanine nucleotide binding protein (G protein), beta polypeptide 1- BG069873 like 1455855_x_at 1.1 2.1 2.5 heterogeneous nuclear ribonucleoprotein A/B BB168316 1434701_at -1.3 2.6 3.5 expressed sequence AW215868 BB795363 1450896_at -1.5 3.2 3.2 Rho GTPase activating protein 5 BM248774 1438908_at -1.2 3.7 4.6 mitogen activated protein kinase kinase kinase 12 BB370469 1418381_at -1.1 2.1 2.3 zinc finger protein 148 X98096 1437995_x_at 1.1 2.5 2.3 septin 7 AV219419 1459854_s_at -1.1 2.3 2.6 dynein light chain Tctex-type 3 AV059518 1439932_at 1.1 2.5 2.3 RIKEN cDNA 3110003A22 gene BQ174624 1433854_at -1.1 2.5 2.8 expressed sequence AW547186 BG064061 1416429_a_at -1.1 2.5 2.3 catalase NM_009804 1437288_at -1.5 2.1 3.0 inositol monophosphatase domain containing 1 BG797423 1435400_at 1.1 2.8 2.3 RIKEN cDNA 2900075B16 gene BF462791 1456573_x_at -1.1 2.1 2.3 nicotinamide nucleotide transhydrogenase BB205930 1459756_at -1.1 2.6 3.0 CCR4-NOT transcription complex, subunit 10 AV301999 1427229_at -1.3 2.3 4.0 3-hydroxy-3-methylglutaryl-Coenzyme A reductase BB123978 1454885_at 1.4 3.0 2.5 cDNA sequence BC063263 BM211194 1434820_s_at 1.5 3.2 2.3 protein kinase inhibitor, gamma AV209892 1437992_x_at 2.1 7.0 3.2 gap junction membrane channel protein alpha 1 BB039269 1430991_at 1.2 2.6 2.3 RIKEN cDNA 1810014B01 gene AK017634 1420083_at 1.2 3.7 2.6 expressed sequence AU016916 AU016916 1438962_s_at 1.6 3.2 2.5 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 31 BB469965 1420042_at 1.7 8.0 4.3 THO complex 1 AW107924 1451313_a_at 1.5 4.0 2.8 RIKEN cDNA 1110067D22 gene BC019131 1427172_at 1.1 2.8 2.5 oral-facial-digital syndrome 1 gene homolog (human) AJ278702 1441733_s_at 1.7 3.2 2.1 nucleoporin 153 C88147 1438560_x_at 1.7 3.7 2.5 chaperonin subunit 4 (delta) AV103196 1433824_x_at 1.2 2.5 2.3 G-rich RNA sequence binding factor 1 BB314772 1439462_x_at 1.4 4.0 2.8 transmembrane emp24-like trafficking protein 10 (yeast) /// similar to AV060550 transmembrane trafficking protein 1440272_at 1.6 4.0 2.1 Eukaryotic translation initiation factor 2, subunit 1 alpha BB232473 1436032_at 1.4 4.3 3.7 Bone marrow macrophage cDNA, RIKEN full-length enriched library, BB201888 clone:I830083F22 product:unclassifiable, full insert sequence 1427152_at 1.3 3.5 2.1 glutamine and serine rich 1 BC021511 1433891_at 1.7 4.3 3.0 leucine-rich repeat-containing G protein-coupled receptor 4 /// BI107632 similar to Leucine-rich repeat-containing G-protein coupled receptor 4 precursor 1438941_x_at 1.4 3.0 2.1 adenosine monophosphate deaminase 2 (isoform L) AV330806 1456729_x_at 1.5 3.7 2.3 regulator of telomere elongation helicase 1 BB218661 1436737_a_at 2.3 9.2 3.0 sorbin and SH3 domain containing 1 BB737680 1439406_x_at 1.2 2.6 2.1 phenylalanine-tRNA synthetase 2 (mitochondrial) BB530332 1456057_x_at 1.5 4.3 2.8 transmembrane protein 109 BB117756 1434452_x_at 1.6 4.0 2.3 eukaryotic translation initiation factor 2a BG797460 1440816_x_at 1.6 4.0 2.3 DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 AV089443 1455496_at 1.6 4.3 2.5 phosphoribosylformylglycinamidine synthase (FGAR AV306055 amidotransferase) 1454688_x_at 1.4 3.7 2.5 transmembrane emp24-like trafficking protein 10 (yeast) /// similar to AV103299 transmembrane trafficking protein 1438786_a_at 1.7 4.6 2.5 RIKEN cDNA 2610021A01 gene /// similar to zinc finger protein 347 AV258879 1440284_at 1.1 3.0 2.3 Transcribed locus, weakly similar to XP_576460.1 PREDICTED: AI506066 similar to hypothetical protein PB402898.00.0 [Rattus norvegicus] 1437942_x_at 1.2 3.2 3.0 epsilon-tubulin 1 AV100095 1454149_a_at 1.4 3.0 2.3 cyclin L2 AK008585 1449641_at 1.1 2.5 2.1 --- AI508733 1438511_a_at 1.9 4.0 2.5 RIKEN cDNA 1190002H23 gene BB408123 1438931_s_at 1.3 3.7 3.0 sestrin 1 AV016566 1436113_a_at 1.2 2.8 2.1 --- BB770696 1457390_at 1.1 3.0 3.2 PRP3 pre-mRNA processing factor 3 homolog (yeast) BG069557 1438992_x_at 1.6 3.7 2.3 activating transcription factor 4 AV314773 1455816_a_at 2.0 4.6 2.5 potassium channel tetramerisation domain containing 3 BB321232 1441178_at 2.0 4.9 3.5 DTW domain containing 2 BB818617 1439419_at 2.1 5.3 2.3 RIKEN cDNA 2310057M21 gene BB189366 1433640_at 1.3 3.5 2.5 Far upstream element (FUSE) binding protein 1 BG070740 1437262_x_at 1.7 4.0 2.5 breast carcinoma amplified sequence 2 AA940256 1451967_x_at 1.9 4.3 2.3 karyopherin (importin) beta 1 BC004096 1455826_a_at 1.3 3.7 2.8 beta-site APP cleaving enzyme 1 BB114336 1459981_s_at 1.1 2.8 2.6 rosbin, round spermatid basic protein 1 AV240926 1437873_at -1.1 2.3 2.6 RIKEN cDNA 6030490I01 gene BB044772 1429332_at -1.0 2.5 2.3 RIKEN cDNA 4632427E13 gene AK019505 1437982_x_at 1.1 2.8 2.3 COX15 homolog, cytochrome c oxidase assembly protein (yeast) BB736240 1435493_at 1.1 3.2 2.6 desmoplakin AV297961 1423747_a_at 1.4 3.5 2.6 pyruvate dehydrogenase kinase, isoenzyme 1 BC027196 1452083_a_at 1.5 3.5 3.0 praja1, RING-H2 motif containing BM199789 1439263_at 1.2 3.7 2.6 fibroblast growth factor inducible 15 BB388301 1433568_at -1.0 3.0 3.0 PAP associated domain containing 4 AV301313 1436708_x_at 1.2 3.0 2.5 minichromosome maintenance deficient 4 homolog (S.