European science review № 1–2 2019 January–February Volume 1 PREMIER Vienna Publishing 2019 European Sciences review Scientific journal № 1–2 2019 (January–February) Volume 1 ISSN 2310-5577 Editor-in-chief Lucas Koenig, Austria, Doctor of Economics International editorial board Abdulkasimov Ali, Uzbekistan, Doctor of Geography Kocherbaeva Aynura Anatolevna, Kyrgyzstan, Doctor of Economics Adieva Aynura Abduzhalalovna, Kyrgyzstan, Doctor of Economics Kushaliyev Kaisar Zhalitovich, Kazakhstan, Doctor of Veterinary Medicine Arabaev Cholponkul Isaevich, Kyrgyzstan, Doctor of Law Lekerova Gulsim, Kazakhstan, Doctor of Psychology Zagir V. Atayev, Russia, Ph.D. of of Geographical Sciences Melnichuk Marina Vladimirovna, Russia, Doctor of Economics Akhmedova Raziyat Abdullayevna, Russia, Doctor of Philology Meymanov Bakyt Kattoevich, Kyrgyzstan, Doctor of Economics Balabiev Kairat Rahimovich, Kazakhstan, Doctor of Law Moldabek Kulakhmet, Kazakhstan, Doctor of Education Barlybaeva Saule Hatiyatovna, Kazakhstan, Doctor of History Morozova Natalay Ivanovna, Russia, Doctor of Economics Bejanidze Irina Zurabovna, Georgia, Doctor of Chemistry Moskvin Victor Anatolevich, Russia, Doctor of Psychology Bestugin Alexander Roaldovich, Russia, Doctor of Engineering Sciences Nagiyev Polad Yusif, Azerbaijan, Ph.D. of Agricultural Sciences Boselin S.R. Prabhu, India, Doctor of Engineering Sciences Naletova Natalia Yurevna, Russia, Doctor of Education Bondarenko Natalia Grigorievna, Russia, Doctor of Philosophy Novikov Alexei, Russia, Doctor of Education Bogolib Tatiana Maksimovna, Ukraine, Doctor of Economics Salaev Sanatbek Komiljanovich, Uzbekistan, Doctor of Economics Bulatbaeva Aygul Abdimazhitovna, Kazakhstan, Doctor of Education Shadiev Rizamat Davranovich, Uzbekistan, Doctor of Education Chiladze George Bidzinovich, Georgia, Doctor of Economics, Doctor of Law Shhahutova Zarema Zorievna, Russia, Ph.D. of Education Dalibor M. Elezović, Serbia, Doctor of History Soltanova Nazilya Bagir, Azerbaijan, Doctor of Philosophy (Ph.D. of History) Gurov Valeriy Nikolaevich, Russia, Doctor of Education Spasennikov Boris Aristarkhovich, Russia, Doctor of Law Hajiyev Mahammad Shahbaz oglu, Azerbaijan, Doctor of Philosophy Spasennikov Boris Aristarkhovich, Russia, Doctor of Medicine Ibragimova Liliya Ahmatyanovna, Russia, Doctor of Education Suleymanov Suleyman Fayzullaevich, Uzbekistan, Ph.D. of Medicine Blahun Ivan Semenovich, Ukraine, Doctor of Economics Suleymanova Rima, Russia, Doctor of History Ivannikov Ivan Andreevich, Russia, Doctor of Law Tashpulatov Salih Shukurovich, Uzbekistan, Doctor of Engineering Sciences Jansarayeva Rima, Kazakhstan, Doctor of Law Tereschenko-Kaidan Liliya Vladimirovna, Ukraine, Doctor of Philosophy Khubaev Georgy Nikolaevich, Russia, Doctor of Economics Tsersvadze Mzia Giglaevna, Georgia, Doctor of Philology Khurtsidze Tamila Shalvovna, Georgia, Doctor of Law Vijaykumar Muley, India, Doctor of Biological Sciences Khoutyz Zaur, Russia, Doctor of Economics Yurova Kseniya Igorevna, Russia, Ph.D. of History Khoutyz Irina, Russia, Doctor of Philology Zhaplova Tatiana Mikhaylovna, Russia, Doctor of Philology Korzh Marina Vladimirovna, Russia, Doctor of Economics Zhdanovich Alexey Igorevich, Ukraine, Doctor of Medicine Proofreading Editorial office Kristin Theissen Premier Publishing s.r.o. Praha 8 – Karlín, Lyčkovo nám. 508/7, PSČ 18600 Cover design E-mail: Andreas Vogel [email protected] Additional design Homepage Stephan Friedman ppublishing.org European Journal of Arts is an international, German/English/Russian language, peer-reviewed journal. It is published bimonthly with circulation of 1000 copies. The decisive criterion for accepting a manuscript for publication is scientific quality. All research articles published in this journal have undergone a rigor- ous peer review. Based on initial screening by the editors, each paper is anonymized and reviewed by at least two anonymous referees. Recommending the articles for publishing, the reviewers confirm that in their opinion the submitted article contains important or new scientific results. Premier Publishing s.r.o. is not responsible for the stylistic content of the article. The responsibility for the stylistic content lies on an author of an article. Instructions for authors Full instructions for manuscript preparation and submission can be found through the Premier Publishing s.r.o. home page at: http://www. ppublishing.org. Material disclaimer The opinions expressed in the conference proceedings do not necessarily reflect those of the Premier Publishing s.r.o., the editor, the editorial board, or the organization to which the authors are affiliated. Premier Publishing s.r.o. is not responsible for the stylistic content of the article. The responsibility for the stylistic content lies on an author of an article. Included to the open access repositories: The journal has the GIF impact factor 1.26 for 2017. © Premier Publishing s.r.o. All rights reserved; no part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, or otherwise, without prior written permission of the Publisher. Typeset in Berling by Ziegler Buchdruckerei, Linz, Austria. Printed by Premier Publishing s.r.o., Vienna, Austria on acid-free paper. BIOTECHNOLOGICAL METHOD OF CONTROLLING THE CONTENT OF GOSSYPOL AND ITS VALUE Section 1. Biotechnology Khojiev Abdurakhim, Candidate of Technical Sciences, Associate Professor of Andijan Machine-Building Institute E-mail: [email protected] BIOTECHNOLOGICAL METHOD OF CONTROLLING THE CONTENT OF GOSSYPOL AND ITS VALUE Abstract. The article presents the results of research on the emergence of gossypol, a new way of managing the content of gossypol and its value. Keywords: Gossypol, cotton, biotechnology, poison, vitamin, soil, manure, water memory, the position of the Earth’s axis. Researchers conducted numerous experiments on the soil produced by uncultivated plants. The change in the com- study of gossypol. Gossypol is a product obtained by process- position of the seed under the action of uncultivated plants ing cotton seeds or from cotton roots (Gossypium sp.), Mal- is called a combinational change. In such cases, uncultivated vaceae family (Malvaceae). Fine-crystalline powder from light plants fulfill the role of mutagenic substance. Mutagenic sub- yellow to dark yellow with a greenish tint. In the light darkens. stances have a direct effect on cotton seed. In order to get rid Practically insoluble in water, slightly soluble in alcohol [1]. of combinational changes in cotton seed, it is necessary to act Gossypol is easily absorbed in the gastrointestinal tract, on it with a biological solution – prepared by mixing cattle slowly released from the body. Symptoms of poisoning (in- manure in water. As a result, 0.22% gossypol is synthesized for creased peristalsis, persistent diarrhea, frequent and painful vitamins and hormones, as well as for strong antibiotics, the urination, then cough, pulmonary edema, venous stasis of the characteristics of which should be studied in further studies. blood) usually appear after a few days [2]. To get rid of the hydrogen ion, which contributes to the To understand how gossypol appears, (Н30С30О8), we combinative changes in the soil of the Earth, it is necessary to conducted a series of experimental studies, analyzes, and ob- treat the soil with livestock manure. Research results show that servations. The following describes the causes of gossypol. if 2 tons of manure are poured onto 1 hectare of land, the effect 1. Changes in the soil. In the soil where uncultivated of uncultivated and cultivated herbs becomes imperceptible. plants are found, the content of hydrogen ions increases and Gossypol, formed by combinational changes, disappears from reacting with chlorine to form chloride acid. H+ + Сl– = HСl. the seed, the oil becomes healing. Gradually, the field is covered with chloride acid. The root 2. The impact of mineral fertilizers. All changes in the soil hairs of such plants dissolve fertilizers, which cannot be dis- structure of the Earth, and the plants planted on the soil and solved and absorbed by the roots of cultivated plants, and in a the harvest obtained from these plants, occurring through the dissolved form absorb mineral fertilizers and thus contribute use of mineral fertilizers can be called ontogenetic or pheno- to an increase in the soil of the hydrogen ion H+. If you sow typic. Under the influence of ontogenetic transformations, cultivated plants without first clearing the soil of the hydro- 0.22% of gossypol is formed in the composition of cotton gen ion, the roots rot, the growth of plants slows down, and seed. To get rid of this gossypol, it is enough to soak the seeds they die. After irrigation, the process of ripening the soil is on a solution of sheep’s manure in water. accelerated, if not plowed in a timely manner, the soil quickly 3. The impact of water memory. Contamination of the hardens. In the cotton field, where uncultivated plants grow, memory of water has a strong influence on the world of plants there are strong changes in the seed and fiber of cotton: the and all living things. In humans and plants, strong mutational content of gossypol in the seed grows. The average value of changes occur. Human health is deteriorating, there are ge- gossypol in the seed, if we conditionally assume equal to 0.7%, netic diseases in front of which medicine is powerless. For [3], then 0.23% of them