Program at a Glance 2016 Conference on Retroviruses and Opportunistic Infections February 22-25, 2016 Boston, Massachusetts 2 CROI 2016 General Information CONTENTS General Information General CROI FOUNDATION ..................................................................2 IAS–USA .............................................................................2 CROI 2016 PROGRAM COMMITTEE .................................................3 Scientific Program Committee.......................................................3 Community Liaison Subcommittee ..................................................4 EXTERNAL REVIEWERS..............................................................5 SCHOLARSHIP AWARDEES ..........................................................7 Young Investigators ...............................................................7 International Scholars ............................................................11 Community Educators ............................................................12 CONTINUING MEDICAL EDUCATION ...............................................13 Accreditation Statement ..........................................................13 Objectives.......................................................................13 Statement of Need ...............................................................13 CME Credit Information ...........................................................13 Claiming CME Credits or a Certificate of Participation ..................................13 Disclosure of Financial Relationships ................................................13 Drug and Product Disclaimer.......................................................13 GENERAL INFORMATION . 14 Overview .......................................................................14 Commercial Support...............................................................6 Americans with Disabilities Act.....................................................14 Emergency Services ..............................................................14 Embargo Policies / Social Media ....................................................14 Welcome Reception ..............................................................14 Wi-Fi ...........................................................................14 Meals ..........................................................................14 Overflow Accommodations for Session Rooms........................................15 Website ........................................................................15 Webcasts and Podcasts ...........................................................15 Affiliated Activity Policies..........................................................15 Mobile App......................................................................15 Badges .........................................................................15 Child Care.......................................................................15 Conference Etiquette .............................................................15 CONFERENCE SERVICES ............................................................16 HOTEL INFORMATION ..............................................................17 ABSTRACT PROCESS................................................................19 ORAL SESSIONS.....................................................................21 POSTER SESSIONS, BY CATEGORY..................................................50 DISCLOSURE OF FINANCIAL RELATIONSHIPS WITH COMMERCIAL CONCERNS ..128 INDEX OF STUDIES RELATED TO WOMEN .........................................134 AUTHOR INDEX ....................................................................137 KEYWORD INDEX ..................................................................165 CONFERENCE SCHEDULE OVERVIEW..................................Inside Back Cover CONVENTION CENTER FLOOR PLANS .......................................Back Cover Printed in USA. © Copyright 2016 IAS–USA/CROI Foundation. All rights reserved. ISBN # 978-0-692-63523-0 CROI 2016 1 General Information CROI FOUNDATION The CROI Foundation is a 501(c)(3) tax-exempt organization in • Has the sole and absolute discretion to veto any policies, the United States that operates exclusively for the charitable and procedures, or actions taken or proposed to be taken by the educational purpose of organizing, promoting, and presenting the CROI PC or the CROI Secretariat that would pose a substantial Conference on Retroviruses and Opportunistic Infections (CROI). risk of preventing the Foundation at any time from qualifying or continuing to qualify as a 501(c)(3) organization or that might Roles and Responsibilities of the CROI Foundation cause the loss of such qualification Volunteer Board of Directors • Oversees the long-term financial and administrative integrity of • Works closely with the CROI Scientific Program Committee (CROI CROI General Information General PC) and IAS-USA to accomplish the mission of CROI • Approves nominations annually for members of the CROI PC and Composition of the CROI Foundation Board of Directors the CROI Chair and Vice Chairs The Board of Directors comprises current and previous CROI Chairs and • Ensures that the CROI PC is responsible for the scientific program Vice Chairs and selected members of the CROI PC. content of CROI • Enters into and oversees the partner agreement with IAS-USA CROI Foundation Board of Directors Constance A. Benson, MD, President Kevin M. De Cock, MD University of California San Diego Centers for Disease Control and Prevention San Diego, CA, United States Nairobi, Kenya John M. Coffin, PhD, Secretary-Treasurer Scott M. Hammer, MD Tufts University Columbia University Medical Center/New York–Presbyterian Hospital Boston, MA, United States New York, NY, United States Elaine J. Abrams, MD John W. Mellors, MD International Center for AIDS Care and Treatment Programs University of Pittsburgh Columbia University Pittsburgh, PA, United States New York, NY, United States Julie M. Overbaugh, PhD Susan P. Buchbinder, MD Fred Hutchinson Cancer Research Center San Francisco Department of Public Health Seattle, WA, United States University of California San Francisco Robert T. Schooley, MD San Francisco, CA, United States University of California San Diego Judith S. Currier, MD, MsC San Diego, CA, United States University of California Los Angeles Richard A. Koup, MD Los Angeles, CA, United States Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health Bethesda, MD, United States IAS–USA The International Antiviral Society–USA is a 501(c)(3) not-for-profit Contact: Executive Director, Donna M. Jacobsen professional education organization. The IAS–USA serves as the Address: 425 California Street, Suite 1450 Conference Secretariat for CROI. San Francisco, CA 94104-2120 The mission of the IAS–USA is to improve the treatment, care, and Phone: 415-544-9400 quality of life for people with HIV, hepatitis C virus, or other viral Website: www.iasusa.org infections through high-quality, relevant, balanced, and needs- oriented education and information for practitioners and scientists who are actively involved in medical care and research. 2 CROI 2016 General Information CROI 2016 SCIENTIFIC PROGRAM COMMITTEE Information General The Scientific Program Committee (PC) is a team of experts in their given field who volunteer to organize the scientific program for CROI. Members are selected based on their area of scientific expertise and their commitment to the mission of the conference. Initial terms are 3 years; subsequent terms are based on previous participation and interest level. Members are nominated by the PC and approved by the CROI Foundation Board of Directors. The “goodwill ambassadors” of CROI, PC members are also responsible for identifying topics and speakers that will ensure innovative programming; strategic planning; abstract review and program development; and organizing, conducting, and convening workshops, symposia, and special sessions. Scientific Program Committee Julie M. Overbaugh, PhD Susan P. Buchbinder, MD Judith S. Currier, MD, MSc CROI 2016 Chair CROI 2016 Vice Chair CROI 2016 Vice Chair Fred Hutchinson Cancer San Francisco Department University of California Research Center of Public Health Los Angeles Seattle, WA, University of California Los Angeles, CA, United States San Francisco United States San Francisco, CA, United States Elaine J. Abrams, MD John M. Coffin, PhD Scott M. Hammer, MD ICAP at Columbia University Tufts University Columbia University Medical New York, NY, United States Boston, MA, United States Center New York-Presbyterian Hospital New York, NY, United States Galit Alter, PhD Kevin M. De Cock, MD Diane V. Havlir, MD Ragon Institute of MGH, MIT, Centers for Disease Control University of California and Harvard and Prevention San Francisco Cambridge, MA, United States Nairobi, Kenya San Francisco, CA, United States Constance A. Benson, MD Wafaa M. El-Sadr, Sharon L. Hillier, PhD University of California MD, MPH Magee-Womens Hospital San Diego ICAP at Columbia University of University of Pittsburgh San Diego, CA, United States New York, NY, United States Medical Center Pittsburgh, PA, United States Bruce J. Brew, MD, MBBS Courtney V. Fletcher, James A. Hoxie, MD St. Vincent’s Hospital PharmD University of Pennsylvania Sydney, Australia University of Nebraska Philadelphia, PA, Medical Center United States College of Pharmacy Omaha, NE, United States Ellen G. Chadwick, MD