ISeptembermmunology 2019 | ISSN 1356-5559 (print) News Inside Immunology: meet our official journal's new Editor in Chief Looking to Parliamentary Tumour Liverpool: engagement: immunology: BSI Congress 2019 Links Day our new Affinity Group www.immunology.org 2 ADVERTISEMENTS Unique Antibodies for Soluble the life science reagents Immune checkpoints company with a difference Vertebrate Antibodies have generated the first commercial antibodies for soluble immune checkpoints sCTLA4, sGITR & sPDL2. 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CTL Treg www.criver.com: translational immuno-oncology platform + We are currently hiring at our R Bristol site. + CELLULAR M1 TAM/ IMMUNOTHERAPEUTIC For more information see: Mφ M2 Mφ https://jobs.criver.com SYNGENEIC MODEL + TUMOUR ANALYSIS PD-1 CTLA-4 LAG-3 TIM-3 TIGIT 3000 VehicleVehicl Lead Biomarkers/ Antie PD-L1 4 Therapeutic Targets 2000 3 Unstim. 2 1000 1 Significance Tumour volume 0 0 Exhausted 0 4 6 8 11 13 15 19 -3 -2 -1 0 1 2 3 4 REVERSING T CELL EXHAUSTION Time (days post-induction) Δ Gene Expression (Nanostring) Immunology News | September 2019 A WORD FROM THE EDITOR 3 ©?Shutterstock/nobeastsofierce Welcome to the autumn issue of Elsewhere, we are building up Immunology News. In this issue, we momentum for the upcoming BSI take a particular focus on the Society’s Congress taking place in Liverpool on official journals. They are a key part of 2–5 December. On pages 8–9, you can our activities to disseminate research read more about what to expect and what with the aim of promoting and advancing we’re looking forward to. It’s a fantastic immunology to foster future innovation, opportunity to network with your peers in addition to providing major financial while taking in the latest cutting-edge support for the activities that we run to immunology research from around the support members’ careers including world – we hope to see lots of you there! Congress, our grant schemes, group Thoughts, feedback and comments as activities and careers initiatives. On pages always welcome to the email below. 14–16, Simon Milling, the new Editor in Chief of Immunology discusses his Best wishes, vision for the journal while our Head of Publishing, Lucy McIvor, takes a look at Jennie Evans Plan S and its implications for the BSI. [email protected] The Team Contents Editorial Advisory Board: FEATURES: Edd James (Southampton) 8 Louisa James (London) Looking to Liverpool: Donald Palmer (London) BSI Congress 2019 Mihil Patel (Cardiff) Managing Editor: Immunology : Meet the Jennie Evans 14 new Editor in Chief Sub Editors: Teresa Prados Rebecca Ramsden Design: Qube Design Associates British Society for Immunology 34 Red Lion Square London 4 Society news WC1R 4SG Tel: +44(0)203 019 5901 19 Congratulations Email: [email protected] www.immunology.org 22 Parliamentary Links Day 20 Representing immunology Enquiries and correspondence: 25 Future focus Jennie Evans: [email protected] 29 Around the BSI groups Advertising queries: 30 Journal news Sarah Green: [email protected] Follow us: Registered charity - 1043255 in England and Wales/SCD047367 in Scotland and britsocimm registered in England and Wales as Introducing our new company 3009533. 29 Tumour Immunology britsocimm Group © 2019 British Society for Immunology britsocimm The views expressed by contributors are not necessarily those of the britsocimm Society, nor can claims of advertisers be guarenteed. The Society, Editorial britishsocietyforimm Board and authors cannot accept liability for any errors or omissions. british-society-for-immunology Immunology News | September 2019 4 SOCIETY NEWS Partnership work VIEW FROM … the BSI. This gave us the opportunity to THE BSI • I’m delighted to announce a new explore new relationships between the partnership for the BSI with the National BSI and Parliamentarians as well build PRESIDENT Cancer Research Institute (NCRI) that links with other scientific societies in brings together immunology and cancer the UK. communities to drive collaborations • With vaccination uptake rarely off the and address current challenges in front pages, we’ve been busy responding immunotherapy. Doug and his team have to many media enquiries to ensure been instrumental in these negotiations we provide a strong, evidence-based and we have some exciting plans in the viewpoint on the importance of pipeline. vaccination to public health. • We’re working hard to increase our Journals engagement on the European stage with EFIS – in particular, looking at how • I would like of offer my sincere thanks our immunology communities can work to Danny Altmann as he steps down together to address vaccine uptake from his long and dedicated service as issues – more information soon. the Editor in Chief of Immunology and • I was involved in discussions with to welcome Simon Milling who assumed American Association of Immunologists this role in June. I also congratulate (AAI) to explore new ways for interaction Danny and his Associate Editors for between the BSI and AAI. This, and the their efforts leading to the increase in work with EFIS, are in part a response to the impact factor of Immunology (now feedback from the membership survey 4.147, its highest ever). You can read It has been six months since my last we carried out last year, where many more about Simon’s future plans for the message to BSI members and it’s of you indicated that it was important journal on pages 12–14. remarkable how quickly time is flying for the BSI to increase international • I would also like to thank and past – it means that I must be enjoying interactions. The Trustees and the congratulate Leonie Taams, the current myself! A lot has happened in this time. BSI office do listen the views of the editor of our other journal Clinical I have benefited greatly by having Peter membership. & Experimental Immunology, Mark Openshaw, our past President, close at Peakman, the past editor, and their External affairs hand to provide advice when needed. Also, editorial team on achieving their highest Doug Brown, our CEO, and his team in • This year, we’ve increased our ever impact factor of 3.711. the BSI office are doing a fantastic job Parliamentary engagement with • The BSI is in an excellent financial position all round to support our members, our significant success – raising issues at present because most of our income activities and introduce new initiatives that around vaccination uptake and the comes from the success of our journals. I will outline in more detail below. policy environment that the UK needs The Trustees and the BSI office are in Key highlights include engagement with to create to allow immunology research discussions about how to maintain the Government Ministers about immunology, to flourish (more on page 20). A group income stream from the journals as the meetings that Doug and I have had with of Trustees and BSI office team recently online publishing environment changes. the European Federation of Immunological attended the Royal Society of Biology’s We will provide more detail of our efforts Societies (EFIS) and our response to Parliamentary Links Day on behalf of and plans on this in due course. counter anti-vaccination issues. The Board of Trustees and the BSI office have an excellent working relationship that makes our interactions both interesting and productive. We are working hard to deliver against our strategic plan, including addressing new plans to diversify our income streams to ensure long-term stability of the organisation. Highlights over the last six months include: BSI elections • As always, there is movement on and off the Board of Trustees as terms end. I would like to thank Edward Chandler for his valuable input over the last four years, as well as Simon Milling who stepped down in May. I’m delighted to welcome the newly elected Trustees, Deborah Dunn-Walters and Allan Mowat (second term), in addition to James Lowe, a new co-opted Trustee. You can BSI Trustee Ann Ager discusses the importance of immunology to the life sciences agenda with Alun Cairns MP, read more about them all on page 6. Secretary of State for Wales at Parliamentary Links Day Immunology News | September 2019 SOCIETY NEWS 5 VIEW FROM THE PRESIDENT (cont.) Events • We’ve had an incredibly busy schedule ‘We're working hard to increase our of BSI Regional and Affinity Group events over last nine months, and I engagement on the European stage with hope many members have benefitted from attending these activities. EFIS - in particular looking at how we can work The Groups are the lifeblood of the organisation and act to bring together together to address vaccine uptake issues.’ our immunology communities. I’d like to personally thank all Group members with young children, and a carers’ grant who give up their time to organise and the BSI office will be there during fund. The details are on our website. these activities – your hard work is the poster sessions and throughout the much appreciated. conference. Do come and visit us for a chat Finally, I hope you have a great summer • I’m looking forward to the BSI and attend our AGM to hear more about and look forward to catching up with as Congress 2019 in December – this has the work we are doing on your behalf.