OriGene Technologies, Inc. OriGene Technologies GmbH 9620 Medical Center Drive, Ste 200 Schillerstr. 5 Rockville, MD 20850 32052 Herford UNITED STATES GERMANY Phone: +1-888-267-4436 Phone: +49-5221-34606-0 Fax: +1-301-340-8606 Fax: +49-5221-34606-11 [email protected] [email protected] AP12449PU-N Polyclonal Antibody to PPAP2C / LPP2 (C-term) - Purified Alternate names: Lipid phosphate phosphohydrolase 2, PAP2-gamma, Phosphatidate phosphohydrolase type 2c, Phosphatidic acid phosphatase 2c Quantity: 0.4 ml Concentration: lot specific Background: PPAP2C is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is similar to phosphatidic acid phosphatase type 2A (PPAP2A) and type 2B (PPAP2B). All three proteins contain 6 transmembrane regions, and a consensus N- glycosylation site. This protein has been shown to possess membrane associated PAP activity. Uniprot ID: O43688 NCBI: 9606 GeneID: 8612 Host / Isotype: Rabbit / Ig Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PPAP2C. Format: State: Liquid purified Ig fraction. Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. Buffer System: PBS with 0.09% (W/V) Sodium Azide as preservative. Applications: ELISA: 1/1,000. Western Blot: 1/50-1/100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. Specificity: This antibody detects PPAP2C (C-term). Species: Human. Other species not tested. Add. Information: Molecular weight: 32574 Da Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. Caution: This product is for research use only. Not for use in diagnostic or therapeutic procedures. General Readings: 1. Long,J.S., Biochem. J. 411 (2), 371-377 (2008) 2. Morris,K.E., J. Biol. Chem. 281 (14), 9297-9306 (2006) 3. Nanjundan,M., Am. J. Physiol. Lung Cell Mol. Physiol. 284 (1), L1-L23 (2003) For research and in vitro use only. Not for diagnostic or therapeutic work. Material Safety Datasheets are available at www.acris-antibodies.com or on request. OG/20130805 1 / 2 AP12449PU-N: Polyclonal Antibody to PPAP2C / LPP2 (C-term) - Purified 4. Zhang,N., Genesis 27 (4), 137-140 (2000) Pictures: Western blot analysis of anti-PPAP2C Antibody (C-term) (Cat.#AP12449PU-N) in NCI-H460 cell line lysates (35ug/lane).PPAP2C(arrow) was detected using the purified Pab. For research and in vitro use only. Not for diagnostic or therapeutic work. Material Safety Datasheets are available at www.acris-antibodies.com or on request. OG/20130805 2 / 2 Powered by TCPDF (www.tcpdf.org).