Supplemental Materials Table 1: SD-based peak activations with age Regions that increase in BOLD SD with age MNI coordinates Cluster size Region Hem X Y Z BSR (in voxels) Superior Frontal Gyrus L -20 20 64 7.35 16 Superior Frontal Gyrus R 22 62 30 7.20 13 Subcallosal area R 3 13 -16 7.10 31 Entorhinal Cortex R 20 11 -24 6.74 17 Mid Orbital Gyrus R 11 65 -12 6.33 14 Medial Temporal Pole L -31 18 -33 6.30 44 Superior Parietal Lobule L -23 -58 71 5.93 32 Inferior Temporal Gyrus R 41 -8 -45 5.63 48 Inferior Temporal Gyrus L -53 -16 -39 5.53 10 Mid Orbital Gyrus L -5 65 -12 5.49 10 Cerebellum (VIII) R 15 -71 -43 5.42 154 Cerebellum (Crus 2) L -47 -59 -45 5.37 22 Cerebellum (Crus 1) R 47 -72 -24 5.32 14 Red nucleus L -6 -26 -14 5.27 12 Caudate Nucleus R 14 7 19 5.19 13 ParaHippocampal Gyrus R 33 -37 -11 4.96 23 Hippocampus L -18 -37 3 4.92 12 Regions that decrease in BOLD SD with age MNI coordinates Cluster size Region Hem X Y Z BSR (in voxels) Lingual Gyrus L -10 -67 2 -14.59 529 Inferior Frontal Gyrus (p. Orbitalis) L -48 20 -7 -7.84 13 Inferior Parietal Lobule R 53 -35 52 -7.21 28 Superior Medial Gyrus R 3 55 5 -7.07 43 Middle Temporal Gyrus L -52 -44 1 -7.02 107 Rolandic Operculum L -57 10 0 -6.84 17 Middle Frontal Gyrus L -25 5 52 -6.33 11 Supplementary Motor Area R 2 -30 56 -5.85 73 Postcentral Gyrus L -58 -19 15 -5.61 39 Angular Gyrus L -37 -61 46 -5.60 15 Middle Temporal Gyrus R 61 -48 11 -5.59 31 Inferior Frontal Gyrus (p. Opercularis) R 52 14 28 -5.41 23 Angular Gyrus R 47 -67 34 -5.06 25 Inferior Frontal Gyrus (p. Opercularis) R 51 19 -3 -5.04 12 Precentral Gyrus L -46 9 35 -5.00 25 Angular Gyrus L -26 -86 40 -4.94 10 Note: Hem = hemisphere; MNI = Montreal Neurological Institute; BSR = bootstrap ratio (salience/bootstrapped standard error). Table 2: Mean-based peak activations with age Regions that increase in BOLD Mean with age MNI coordinates Cluster size Region Hem X Y Z BSR (in voxels) Middle Temporal Gyrus L -61 -6 -24 -5.05 10 Regions that decrease in BOLD Mean with age MNI coordinates Cluster size Region Hem X Y Z BSR (in voxels) Superior Parietal Lobule L -17 -57 61 12.28 397 Inferior Temporal Gyrus L -50 -54 -12 9.66 556 Middle Occipital Gyrus R 37 -75 14 8.22 44 Inferior Frontal Gyrus (p. Triangularis) L -48 46 6 7.57 125 Inferior Temporal Gyrus R 47 -55 -5 7.28 110 Middle Occipital Gyrus L -30 -86 30 7.26 23 Precentral Gyrus L -31 -1 54 7.23 41 Precentral Gyrus R 43 -16 48 6.96 90 Superior Temporal Gyrus L -62 -31 17 6.84 40 Cerebellum (VIII) L -29 -50 -52 6.59 54 Inferior Frontal Gyrus (p. Triangularis) R 55 29 12 6.40 50 Cerebellum (IX) R 16 -45 -53 6.24 14 Red nucleus L -6 -26 -14 6.23 71 Postcentral Gyrus L -37 -16 43 5.99 12 Anterior Cingulate Cortex R 7 8 28 5.71 24 Middle Cingulate Cortex R 11 -22 37 5.62 19 Inferior Parietal Lobule L -41 -47 43 5.59 50 Inferior Frontal Gyrus (p. Opercularis) L -53 11 8 5.49 54 Middle Frontal Gyrus R 43 -4 59 5.11 73 Insula Lobe L -37 13 -2 4.96 17 Insula Lobe R 39 15 7 4.82 11 Calcarine Gyrus L -14 -73 12 4.12 18 Temporal Pole R 60 6 3 3.84 10 Note: Hem = hemisphere; MNI = Montreal Neurological Institute; BSR = bootstrap ratio (salience/bootstrapped standard error). .