PSYCHOPHARMACOLOGY THURSDAY-SUNDAY, OCTOBER 22-25, 2015 Westin Copley Place • 10 Huntington Ave., Boston, MA COURSE DIRECTORS: Jerrold F. Rosenbaum, MD Maurizio Fava, MD Psychiatrist-in-Chief Director, Division of Clinical Research of Massachusetts General Hospital the MGH Research Institute Stanley Cobb Professor of Psychiatry Executive Vice Chair, Department of Psychiatry Harvard Medical School Executive Director, MGH Clinical Trials Network and Institute Massachusetts General Hospital Slater Family Professor of Psychiatry Harvard Medical School Massachusetts General Hospital MGHCME.org Psychiatry Academy PSYCHOPHARMACOLOGY Thursday–sunday • OcTOber 22-25, 2015 WesTin cOpley place • 10 hunTinTOn ae, bOsTOn, Ma WELCOME Welcome to the Massachusetts General Hospital Psychiatry Academy’s 39th Annual Psychopharmacology Course. This course highlights the latest research findings in psychopharmacology and their clinical applications across the spectrum of psychiatric disorders, including, anxiety, ADHD, depression, bipolar disorder, eating disorders, OCD, psychosis, PTSD, substance abuse, and more. TARGET AUDIENCE This program is intended for psychiatrists, primary care and family practice physicians, psychologists, nursing professionals, and social workers. COMPLIMENTARY BREAKFAST AND COFFEE BREAKS Complimentary breakfast and coffee breaks will be available to course participants. Please note: lunch and dinner are not provided and are on your own. EVALUATION FORMS/CME/CEU CERTIFICATES Every participant needs to complete the activity evaluation online to claim CME/CEU credits for this course. Please refer to the Evaluation and CME Information document in this syllabus for more information. We strongly encourage you to complete the evaluation, even if you do not require a certificate. Your comments are important to us as we plan future programs. The link to claim credit is as follows: www.mghcme.org/psychopharm QUESTIONS Opportunity for questions will be provided at the end of each module during the panel discussion. Please write your questions on the index cards provided. Cards will be collected during the last 15 minutes of the lecture prior to the start of the panel discussion. Experience has shown that this method is preferable to that of spontaneous questions. COPYRIGHT The course materials and PowerPoint presentations are copyright protected by Massachusetts General Hospital, Department of Psychiatry, Division of Postgraduate Education, the faculty members and the appropriate authors. Videotaping and audiotaping are not allowed. Thank you for your cooperation. CELLULAR TELEPHONES & PAGERS During the lectures, we ask that you turn your cell phones and pagers to vibrate or off. We also ask that you do not talk on your cell phones inside the meeting room. Thank you for your cooperation. CONTACT INFORMATION For questions or comments, please contact MGH Psychiatry Academy member services at 866-644-7792 or [email protected] Massachusetts General Hospital MGHCME.org Psychiatry Academy LEARNING OBJECTIVES At the end of this educational activity, participants should be able to: . Identify rational, evidence-based pharmacologic and non-pharmacologic therapies for patients with unipolar, bipolar, treatment-resistant, and post-partum depression. Assess obstacles to maintenance of long-term recovery and the liability issues associated with psychopharmacology. Discuss diagnostic and evidenced-based treatment strategies for pediatric onset mood disorders. Compare the neurobiology and evidence-based treatment approaches to addiction, anxiety, schizophrenia, and mood disorders. Review the course and treatment of psychiatric disorders during pregnancy and menopause. Recognize psychosocial issues and evidence-based treatment modalities for eating and sleep disorders. Analyze drug interactions and the pharmacotherapy of adult ADHD and geriatric disorders. ACCREDITATION This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of McLean Hospital and Massachusetts General Hospital. McLean Hospital is accredited by the ACCME to provide continuing medical education for physicians. McLean Hospital designates this live activity for a maximum of 31.25 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activity. PSYCHOLOGISTS The Massachusetts General Hospital Department of Psychiatry is approved by the American Psychological Association to sponsor continuing education (CE) for psychologists. The Massachusetts General Hospital Department of Psychiatry maintains responsibility for this program and its content. This offering meets the criteria for 31.25 Continuing Education (CE) credits for psychologists. REGISTERED NURSES This program meets the requirements of the Massachusetts Board of Registration in Nursing (244 CMR 5.00) for 31.25 contact hours of nursing continuing education credit. Advance practice nurses, please note: Educational activities which meet the requirements of the ACCME (such as this activity) count towards 50% of the nursing requirement for ANCC accreditation. SOCIAL WORKERS This program has been approved for 30.5 Social Work Continuing Education hours for relicensure, in accordance with 258 CMR. Collaborative of NASW and the Boston College and Simmons Schools of Social Work Authorization Number D 71097. RISK MANAGEMENT (**Sessions qualify for risk management credit) Physicians: 1.5 credits meet the criteria of the Massachusetts Board of Registration in Medicine for risk management study. Other CE Licenses: Other Providers can claim a Participation Certificate upon successful completion of this course. Participation Certificates will specify the title, location, type of activity, date of activity, and number of AMA PRA Category 1 Credits™ associated with the activity. Providers should check with their regulatory agencies to determine ways in which AMA PRA Category 1 Credits™ may or may not fulfill continuing education requirements. Providers should also consider saving copies of brochures, agenda, and other supporting documents. Massachusetts General Hospital MGHCME.org Psychiatry Academy AGENDA Thursday, October 22, 2015 4:00 – 8:00PM Neuromodulation 2015: State of the Art THIS IS A TICKETED EVENT, DINNER SERVED Friday, October 23, 2015 7:00 – 8:00AM Registration &Continental Breakfast 8:00 – 8:15AM Welcome Maurizio Fava, MD 8:15 – 8:30AM Introduction and Overview Jerrold F. Rosenbaum, MD MODULE TOPIC – MOOD DISORDERS 8:30– 9:15AM Bipolar Depression Andrew A. Nierenberg, MD 9:15 – 10:00AM Bipolar Long Term Management Roy H. Perlis, MD, MSc 10:00 – 10:15AM Coffee Break 10:15 – 11:00AM Treatment Resistant Depression Maurizio Fava, MD 11:00 – 12:00PM Panel Discussion Moderator: Jerrold F. Rosenbaum, MD Panelists: Andrew A. Nierenberg, MD; Roy H. Perlis, MD, MSc; Maurizio Fava, MD 12:00 – 1:00PM Lunch (onyourown) MODULE TOPIC – ANXIETY/OCD 1:00 – 1:45PM OCD Michael A. Jenike, MD 1:45 – 2:30PM PTSD Naomi M. Simon, MD, MSc 2:30 – 3:15PM Anxiety Disorders and Treatments Kerry J. Ressler, MD, PhD 3:15 – 3:30PM Coffee Break 3:30 – 4:15PM Obsessive-Compulsive Related Disorders Lisa M. Zakhary, MD, PhD Massachusetts General Hospital MGHCME.org Psychiatry Academy 4:15 – 5:00PM Panel Discussion Moderator: Michael A. Jenike, MD Panelists: Kerry J. Ressler, MD, PhD; Lisa M. Zakhary, MD, PhD; Naomi M. Simon, MD, MSc 5:00 – 6:30PM Dinner (onyourown) Friday, October 23, 2015: Evening Seminars 6:30 – 7:30PM Friday Evening Seminars (please pick two): 7:30 – 8:30PM Seminars will begin at 6:30 PM and will repeat at 7:30 PM. Natural Medications for Psychiatric Disorders Albert S. Yeung, MD, ScD (Adams/Baltic, 7th Floor) Suicide Theodore A. Stern, MD (St. George A-B, 3rd Floor) The Neurobiology of Addiction Jodi Gilman, PhD (St. George C, 3rd Floor) Psychopharmacology of Sleep Disorders Matt T. Bianchi, MD, PhD, MMSc (America Ballroom, 4th Floor) The Neurobiology of Mood and Psychotic Disorders Dost Öngür, MD, PhD (Empire, 7th Floor) Cognitive-Behavioral Therapy to Augment Psychopharmalogical Therapy Michael W. Otto, PhD (St. George D, 3rd Floor) Massachusetts General Hospital Psychiatry Academy MGHCME.org Saturday, October 24, 2015 7:00 – 8:00AM Continental Breakfast 8:00 – 8:10AM Welcoming Remarks David H. Rubin, MD MODULE TOPIC – PSYCHOSIS 8:10 – 8:55AM First-Episode Psychosis and Schizophrenia Oliver Freudenreich, MD, FAPM 8:55 – 9:30AM Drug Interactions Jonathan E. Alpert, MD, PhD 9:30 – 9:45AM Coffee Break 9:45 – 10:30AM Management of Side-Effects of Antipsychotics David C. Henderson, MD 10:30 – 11:30AM Panel Discussion Moderator: David H. Rubin, MD Panelists: Oliver Freudenreich, MD, FAPM; David C. Henderson, MD; Jonathan E. Alpert, MD, PhD 11:30 – 12:30PM Lunch (onyourown) MODULE TOPIC – NEW THERAPIES 12:30 – 1:30PM Stimulation and/or Surgical Approaches to Psychiatric Illness Darin D. Dougherty, MD, MMSc 1:30 – 2:30PM New Treatments for Bipolar Disorder Roy H. Perlis, MD, MSc 2:30 – 2:45PM Coffee Break 2:45 – 3:45PM New Treatments for Depression George I. Papakostas, MD 3:45 – 4:30PM New Antipsychotics David C. Henderson, MD 4:30 – 5:15PM Panel Discussion Moderator: David C. Henderson, MD Panelists: Roy H. Perlis, MD, MSc; George I. Papakostas, MD 5:15 – 6:30PM Dinner (onyourown) Massachusetts General Hospital MGHCME.org Psychiatry Academy Saturday, October 24, 2015: Evening Seminars 6:30 – 7:30PM Saturday Evening