Curriculum Vitae (C. Xiao) Chuan Xiao, PhD Professor of Biochemistry Department of Chemistry and Biochemistry The University of Texas at El Paso 500 West University Ave. CCSB 2.0310 El Paso, TX 79968, USA Email: [email protected] Webpage: http://utminers.utep.edu/cxiao Office Tel: 915.747.8657; Fax: 915.747.5996 Education 2005-2008 Postdoc Department of Biological Sciences, Purdue University, West Lafayette, IN 1998-2005 Ph.D. Department of Biological Sciences, Purdue University, West Lafayette, IN Program: Biochemistry and Molecular Biology, GPA: 3.9 out of 4.0 1995-1998 M.S. Department of Biochemistry, Fudan University, Shanghai, P.R.China Major: Biochemistry, GPA: 3.6 out of 4.0 1991-1995 B.S. Department of Biochemistry, Fudan University, Shanghai, P.R. China Major: Biochemistry, GPA: 3.5 out of 4.0 Minor: Electronics and Information system, GPA: 3.9 out of 4.0 Professional Experiences 2021- Professor; Department of Chemistry and Biochemistry, University of Texas at El Paso, El Paso, TX. Current Major Research Projects: Using structural techniques such as X-ray crystallography and cryo-EM to study (1) Giant marine viruses (CroV and AaV); (2) A virophage integrase; (3) Mammalian circadian components; (4) GAM1, a viral protein globally inhibits cellular SUMOylation; (5) Drugs for emerging enteroviruses; and (6) Developing RIVEM2 for structural analyses. Current funding: PI of one NIH-R01 grant; co-investigator of one NIH U54 grant; co-PI of one NSF MRI grant; local PIs for three multiple PI NIH U24 cryo-EM consortium grants. Accomplishments: 1 publication 2015-2021 Associate Professor; Department of Chemistry and Biochemistry, University of Texas at El Paso, El Paso, TX. Accomplishments: finished one NIH SC3 grant as PI and one NSF-MRI grant as co-PI; 16 publications(9 corresponding author, 6 with students including one with many undergraduates); 7 conference proceedings; 3 papers under preparation; two cryo-EM reconstruction of giant marine viruses CroV and AaV to EMDB; currently supervise research of three Ph.D. students, one Master student and 10 undergraduate students; have supervised one post-doctoral researcher, 8 graduate students, 59 undergraduate students; currently serving or have served on committee of 9 M.S. students and 11 Ph.D. students. 2008-2014 Assistant Professor; Department of Chemistry, University of Texas at El Paso, El Paso, TX. Accomplishments: 12 publications; 1 conference proceeding; PI of one, co-PIs of two, and collaborators of two federal grants; PI of four internal grants; graduated one Ph.D. student, two M.S. students; have supervised research of one unfinished Ph.D. student (due to severe sickness of tumor), two M.S. students (non-thesis), 30 undergraduate students, and 9 high-school students; serving or have served on 1 | Page Curriculum Vitae (C. Xiao) committee of 11 M.S. students and 10 Ph.D. students. 2005-2008 Post-Doctoral Research Associate; Department of Biological Sciences, Purdue University, West Lafayette, IN. Projects: “Cryo-EM reconstruction of the giant Mimivirus”, “High resolution cryo-EM reconstruction of Sindbis virus deglycosylation mutants”, and “Structure studies of the interaction between Coxsackievirus A21(CVA21) and its receptor DAF and ICAM-1”. Mentor: Michael Rossmann Accomplishments: 5 publications; one cryo-EM reconstruction of giant Mimivirus to EMDB; supervised research of two undergraduate students. 1998-2005 Graduate Student Researcher for Ph.D. degree; Department of Biological Sciences, Purdue University, West Lafayette, IN. Dissertation Title: “Interaction between three picornaviruses and their common receptor ICAM-1”. Advisor: Michael G. Rossmann Accomplishments: 5 publications; three X-ray structures of common cold virus CVA21 submitted to PDB and three cryo-EM reconstruction of common cold viruses (CVA21, HRV16 and HRV14) with their receptor ICAM-1 to EMDB; One published program RIVEM and about 10 different cryo-EM programs for the group; webmaster of the group. 1995-1998 Graduate Student Researcher for M.S. degree; State Satellite Laboratory of Rice Genome Project, Fudan University, Shanghai, China. Thesis Title: “A novel calmodulin-like protein gene in rice which has an unusual prolonged C-terminal sequence carrying a putative prenylation site”. Mentor: Kaimin Cao Accomplishments: 2 publications; 2 complete cDNA sequences (GAPDH and a novel Calmodulin-like protein), 1 complete genomic sequence (a novel Calmodulin-like protein); and 200 ESTs of Rice. 1996-1998 Computer and Network System Administrator; State Key Laboratory of Genetic Engineering, Fudan University, Shanghai, China. Director: Shunde Wang Accomplishments: Technique leader in the construction of campus network of three buildings of the School of Life Sciences; System administrator of computer servers; taught graduate level class about usage of biological software. 1992-1995 Undergraduate Research for B.S. Degree; Satellite Laboratory of Rice Genome Project, Fudan University, Shanghai, China. Thesis Title: “Sequencing of the cDNA Encoding the 16 kDa Subunit of V-ATPase from Rice and Homology Searching”. Mentor: Kaimin Cao Accomplishments: help to build the new lab; 1 complete cDNA sequence (16kDa subunit C of V-ATPase) and about 100 ESTs of Rice; established internet submission of EST into GenBank; repair and maintain the lab instruments. Professional Affiliation 2021- lifetime member of Society of Chinese Bioscientists in America/Virology Division (ACVA) 2020- associate editor, Journal of Medical Virology 2017- member, UTEP student chapter advisor, American Society for Biochemistry and Molecular Biology (ASBMB) 2016- member, Society for Research of Biological Rhythms (SRBR) 2015- review editor in Virology, Frontiers in Microbiology 2010-2013 member of American Chemical Society (ACS) 2009-2011 member and admission committee of Sigma Xi, 2 | Page Curriculum Vitae (C. Xiao) 2002- member of Microscopy Society of America (MSA) 2008-2012 member of American Association for the Advancement of Science (AAAS) 2001- associated (to 2008) and then lifetime full member of American Society for Virology (ASV) Honors and Sscholarships 2020 Texas Regents’ Outstanding Teaching Award, UT System, Austin, TX, USA. 2019 Mentoring Award for Excellence in Student Research Mentoring, College of Science and BUILDing SCHOLARS, UTEP, El Paso, TX, USA. 2018 One of the five university level nominees to Texas Regents’ Outstanding Teaching Award, UTEP, El Paso, TX, USA. 2016 May Graduating Undergraduate Student Choice Award for Outstanding Teaching in College of Science, College of Science, UTEP, El Paso, TX, USA. 2015 December Graduating Undergraduate Student Choice Award for Outstanding Teaching in Department of Chemistry, College of Science, UTEP, El Paso, TX, USA. 2015 May Graduating Undergraduate Student Choice Award for Outstanding Teaching in Department of Chemistry, College of Science, UTEP, El Paso, TX, USA. 2008 Postdoctoral travel award, 27th Annual Meeting of American Society for Virology, Ithaca, NY, USA. 2007 One of three selected talks from poster session, Workshop on Advanced Topics in EM Structure Determination, San Diego, CA, USA. 2006 Committee Appreciation Poster Award, 3rd International Conference on Structural Analysis of Supramolecular Assemblies by Hybrid Methods, Lake Tahoe, CA, USA. 2002 MSA Presidential Student Award of Microscopy & Microanalysis, Quebec City. Canada. 2001 Graduate student travel grant award, 20th Annual Meeting of American Society for Virology, Madison, WI, USA. 2000 Second Place Award, Poster Session of the 6th Biophysics and Cellular Biology Symposium, Purdue University, West Lafayette, IN, USA. 2000 Highest Score, Doctoral Qualifying Examination, Biochemistry and Molecular Biology Program, Purdue University, West Lafayette, IN, USA. 1997 The only second year master’s degree student earning Dongs' Orient Scholarship, First rank scholarship, Fudan University, Shanghai, China. 1996 Highest scholarship of first year master’s degree student, GuangHua Scholarship, Fudan University, Shanghai, China. 1995 Selected one of five excellent graduates in a forty-student class, Undergraduate, Fudan University, Shanghai, China 1990-1995 Third rank scholarship as freshman, Second Rank Scholarship as Sophomore and Senior student, Undergraduate, Fudan University, Shanghai, China. Publications (* = post-doctoral researcher from my group; * = graduate student from my group; * = undergraduate student from my group; § = as corresponding or co-corresponding author) My citation sites: ORCID, Research ID, GOOGLE Scholar, My NCBI My Publication on My Webpage, My Animation (Movies) Gallery Manuscrips Currently in Preparation: • Rahaman, A., Chacon, M.*, Arbogast, M.*, Fischer, M.G., Xiao, C. §, Li, C., “Study Cafeteria roenbergensis predating behavior on bacteria with two-photon fluorescence microscopy” • Xian, Y.*, Moreno, B.*, Chacon, M.*, Duer, B.*, Ray, S. *, Fischer, M.G., Xiao, C. § “The characterization of a recombinant virophage integrase” • Knapka, J.*, Jain, R.*, Xiao, C. § “RIVEM 2: A Comprehensive Software tool for creating 3D to 2D plots of Protein Surface.” 3 | Page Curriculum Vitae (C. Xiao) Published Manuscripts: Recent Invited book chapter from Total of 2: 1. Xian, Y.*, Xiao, C. § (2020) “Current capsid assembly models of icosahedral Nucleocytoviricota viruses.” Advances in Virus Research, 108: 275-313, ePublished Online with doi.org/10.1016/bs.aivir.2020.09.006. Recent Invited Review Articles from Total of 5: 1. Xiao, C. § (2021). "In Memory of Michael G. Rossmann: A Wise Man with a