touchREVIEWS in Endocrinology VOLUME 17 • ISSUE 1 • 2021 EDITOR-IN-CHIEF: JOHN DOUPIS The Role of Individualized Exercise Prescription in Type 2 Diabetes Management John Doupis, Konstantinos Karras and Konstantinos Avramidisan Dapagliflozin as Adjunct Therapy to Insulin in Patients with Type 1 Diabetes Mellitus: Efficacy and Safety of this Combination Johan H Jendle, Francisco Javier Ampudia-Blasco, Martin Fuchtenbusch and Paolo Pozzilli Clinical, Metabolic and Hormonal Profiles of Bangladeshi Adolescents with Polycystic Ovary Syndrome ABM Kamrul-Hasan, Fatema Tuz Zahura Aalpona and Shahjada Selim Potential Role of Dexamphetamine in the Treatment of Non-alcoholic Fatty Liver Disease: Hopes and Pitfalls CS Gautam, Jatin Sharma, Mandeep Singla, Ilmjot Kaur Tiwana and Harmanjit Singh SSN 2752-5457 eI www.touchENDOCRINOLOGY.com touchREVIEWS in Endocrinology Cover image: Fat cells – 3d rendered illustration Volume 17 • Issue 1 By xrender © shutterstock.com Editorial Directors Helen Fowler Editor-in-Chief Gina Furnival Commissioning Editors John Doupis Director of the Diabetes Division of Iatriko Palaiou Falirou Medical Center and the Internal Medicine and Diabetes Department, Sophie Nickelson (Therapy Lead) the NS Naval Hospital, Athens, Greece Katey Gabrysch Victoria Jones Editorial Workflow Lisa Glass Heather Hall Section Editors Joanna Macdiarmid Editorial Assistant George P Chrousos Ashley Grossman Professor and Chairman, First Department of Professor of Endocrinology, Oxford Centre for Diabetes, Endocrinology and Louise Taylor Paediatrics, University of Athens Medical School, Metabolism, University of Oxford, Oxford, UK Athens, Greece Design Manager Chantal Mathieu Julie Stevenson Neil Gittoes Professor of Medicine, Catholic University of Leuven, Leuven, Belgium Head, Centre for Endocrinology, Diabetes and Group Head Medical & Editorial Metabolism, University Hospitals Birmingham Alex Miras and University of Birmingham, Birmingham, UK Senior Clinical Lecturer in Endocrinology, Imperial College London, London, UK Nicola Cartridge E: [email protected] T: +44 (0)20 7193 3186 CEO & Managing Director Editorial Board Barney Kent E: [email protected] T: +44 (0)20 7193 3009 S Faisal Ahmed Burkhard Göke Enrico Papini Samson Gemmell Chair of Child Health, Medical Director and CEO, University Professor of Endocrinology, ‘La Sapienza’ Head of Strategic Partnerships Consultant in Paediatric Endocrinology, Medical Center Hamburg-Eppendorf, University of Rome Medical School, Rome, Caroline Markham School of Medicine, University of Glasgow, Hamburg, Germany Italy Glasgow, UK E: [email protected] Anthony M Heagerty Ralf Paschke T: +44 (0)20 7193 3704 Philippe Bouchard Professor, University of Manchester, Professor of Internal Medicine and Professor and Chairman, Department of Manchester, UK Endocrinology, Leipzig University, Leipzig, Endocrinology, Hospital Saint Antoine and Germany University Pierre and Marie Curie, Paris, Jens Juul Holst France Professor of Medical Physiology, Vera Popovic-Brkic touchREVIEWS in Endocrinology wishes to thank the organ- University of Copenhagen, Copenhagen, Professor of Medicine, University of isations below for their assistance. This does not constitute Francesco Chiarelli Belgrade School of Medicine, Belgrade, Professor of Paediatrics, D’Annunzio Denmark any official endorsement. Serbia University of Chieti-Pescara, Chieti, Italy Ilpo Huhtaniemi Annamaria Colao Michael B Ranke Emeritus Professor of Reproductive Professor, University Children’s Hospital, Full Professor, University of Naples Endocrinology, Faculty of Medicine, Federico II, Naples, Italy Eberhard Karls University, Tübingen, Department of Surgery & Cancer, Germany Thomas Danne Imperial College London, London, UK Professor of Paediatrics, Children’s Hospital João Filipe Raposo ‘Auf der Bult’, Hannover, Germany Anna-Lena Hulting Assistant Professor of Public Health, Professor, Endocrinology, Metabolism and Medical Faculty of New University of Lisbon; Deep Dutta Diabetology, Karolinska University Hospital, Clinical Director, Protective Association of Senior Endocrinologist, Department of Solna, Sweden Diabetics of Portugal, Lisbon, Portugal Endocrinology, CEDAR Super-specialty Clinics, New Delhi, India Sanjay Kalra Martin Silink Ulla Feldt-Rasmussen Executive Editor, JoSH Diabetes, Professor of Paediatric Endocrinology, Professor, Department of Endocrinology, Bharti Hospital, Karnal, India University of Sydney; Children’s Hospital, Centre of Cancer and Organ Diseases, Westmead, Sydney, Australia Robert Knutzen University of Copenhagen, Copenhagen, Johannes WA Smit Denmark President and CEO, Pituitary Network Association (PNA), Thousand Oaks, Professor and Chairman, Department of Anne-Marie Felton CA, USA Endocrinology, Leiden University Medical President, Federation of European Nurses Centre, Leiden, Netherlands in Diabetes (FEND), Newcastle On Tyne, UK Andrea Lenzi Full Professor of Endocrinology, Solomon Tesfaye Angus Forbes Consultant Physician and Honorary Professor of Diabetes Nursing and Chair, ‘La Sapienza’ University of Rome, Rome, Italy Professor of Diabetic Medicine, University Foundation of European Nurses in Diabetes of Sheffield, Sheffield, UK (FEND), King’s College London, London, UK Rayaz A Malik Tommaso Simonicini Baptist Gallwitz Professor of Medicine at Weill Cornell Professor of Obstetrics and Gynaecology, Professor of Medicine, Eberhard Karls Medical College, Doha, Qatar & New York Department of Clinical and Experimental University of Tübingen, Tübingen, Germany City, New York, NY, USA Medicine, University of Pisa, Pisa, Italy Andrea R Genazzani Jean Claude Mbanya Professor and Director, Department Peter Trainer Professor of Medicine and Endocrinology, of Reproductive Medicine and Child Professor of Endocrinology, University of University of Yaoundél, Cameroon, Africa Development, University of Pisa, Pisa, Italy Manchester, Manchester, UK MEDICAL Ezio Ghigo Furio Pacini Graham R Williams Professor, Division of Endocrinology and Professor of Endocrinology, University of Professor of Endocrinology, Imperial College Metabolism, University of Turin, Turin, Italy Siena, Siena, Italy London, London, UK MEDIA www.touchmedicalmedia.com All information obtained by Touch Medical Media and each of the contributors from various sources is as current and accurate as possible. 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ISSN: 2752-5457 TOUCH MEDICAL MEDIA touchREVIEWS in Endocrinology Established: December 2005 Frequency: Bi-annual Current edition: Volume 17 Issue 1 Aims and Scope Submissions and Instructions for Authors • touchREVIEWS in Endocrinology enables time-pressured • The Managing Editor commissions articles with guidance from physicians to stay abreast of major advances and opinion in the Editorial Board and unsolicited articles are welcomed. endocrine practice in Europe. • The Managing Editor is always keen to hear from authors • touchREVIEWS in Endocrinology comprises balanced and wishing to discuss potential submissions, and will give due comprehensive articles, addressing the most important and consideration to any proposals. Please contact the Managing salient developments in the endocrinology field. 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