Anti-PTGES2 (aa 86-135) polyclonal antibody (DPABH-25479) This product is for research use only and is not intended for diagnostic use. PRODUCT INFORMATION Antigen Description Isomerase that catalyzes the conversion of unstable intermediate of prostaglandin E2 H2 (PGH2) into the more stable prostaglandin E2 (PGE2) form. May also have transactivation activity toward IFN-gamma (IFNG), possibly via an interaction with CEBPB; however, the relevance of transcription activation activity remains unclear. Immunogen Synthetic peptide corresponding to a region within internal sequence amino acids 86-135 (VAKYMGAAAM YLISKRLKSR HRLQDNVRED LYEAADKWVA AVGKDRPFMG) of Human PTGES2 (NP_945176). Isotype IgG Source/Host Rabbit Species Reactivity Human Purification Immunogen affinity purified Conjugate Unconjugated Applications WB Format Liquid Size 50 μg Buffer Constituents: 97% PBS, 2% Sucrose Preservative None Storage Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. GENE INFORMATION Gene Name PTGES2 prostaglandin E synthase 2 [ Homo sapiens ] Official Symbol PTGES2 Synonyms PTGES2; prostaglandin E synthase 2; C9orf15, chromosome 9 open reading frame 15; 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved FLJ14038; GATE-binding factor 1; microsomal prostaglandin E synthase-2; membrane- associated prostaglandin E synthase 2; gamma-interferon-activated transcriptional element- binding factor 1; GBF1; GBF-1; PGES2; C9orf15; mPGES-2; MGC11289; Entrez Gene ID 80142 Protein Refseq NP_001243264 UniProt ID A6NHH0 Chromosome Location 9q34.12 Pathway Arachidonic acid metabolism; Eicosanoid Synthesis; IFN-gamma pathway; Metabolic pathways; prostanoid biosynthesis; Function DNA binding; electron carrier activity; isomerase activity; prostaglandin-E synthase activity; protein disulfide oxidoreductase activity; 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved.