Supplemental Table 1. GAPDH 5'- CAT GTT CGT CAT GGG TGT GAA CCA -3' (fwd) 5'- AGT GAT GGC ATG GAC TGT GGT CAT -3' (rev) EPB4L3 5'- AGT GAG TTC CGC TTT GCA CCA AAC -3' (fwd) 5'- AAA TGC ATC TCT GCT TCT GCT GGC -3' (rev) UBE2L6 5'- AGT ATC CGT TCA AGC CTC CCA TGA -3' (fwd) 5'- AAG GCT TCC AGT TCT CAC TGC TGA -3' (rev) IER3 5'- TCT TTC TGC TGC TCA CCA TCG TCT -3' (fwd) 5'- GCT CCG AAG TCA GAT TAA AGG GCT -3' (rev) ALPL 5'- TCG CCT ACC AGC TCA TGC ATA ACA -3' (fwd) 5'- TGA AGC TCT TCC AGG TGT CAA CGA -3' (rev) GADD45A 5'- TCT GCA GAT CCA CTT CAC CCT GAT -3' (fwd) 5'- TGA ATG TGG ATT CGT CAC CAG CAC -3' (rev) SSX1 5'- AAG TCA CCC TCC CAC CTT TCA TGT -3' (fwd) 5'- ACC TGA ATC CTG CGG TTA TGG TCA -3' (rev) DDP7 5'- TCA GTG CCT ACC TGA GGA TGA AGT -3' (fwd) 5'- AGT CCT TGA TCT GTC GGA ACG CTT -3' (rev) FAPB3 5'- GCA TGA CCA AGC CTA CCA CAA TCA -3' (fwd) 5'- GCA GGT GAA CAA GTT TCC CTC CAT -3' (rev) TGFBI 5'- TGA GAG ACC TGC TGA ACA ACC ACA -3' (fwd) 5'- ATT GGA GAT GAT CGC CTT CCC GTT -3' (rev) NCALD 5'- AGG ACT TGC TGG AAA GCA CAG ACT -3' (fwd) 5'- GTG CGG AAG ACA TGC TCT GCA AAT -3' (rev) S100A2 5'- AAG GGA CTT CTG CAC AAG GAG C -3' (fwd) 5'- AAG GCA GAA CCA TTA GGC AGG -3' (rev) Supplemental Table 2 A: Doxorubicin Gene bank Gene Gene name Fold accesion symbol difference number NM_014367 E2IG5 growth and transformation-dependent protein 2.1 NM_017740 FLJ20279 zinc finger, DHHC domain containing 7 1.6 NM_024061 MGC5521 vav-1 interacting Kruppel-like protein 2.5 NM_006541 TXNL2 thioredoxin-like 2 1.9 NM_020640 RP42 RP42 homolog 2.0 NM_021975 RELA v-rel reticuloendotheliosis viral oncogene homolog A 1.8 NM_017646 IPT tRNA isopentenyltransferase 1 1.6 AB037760 ZER6 zinc finger protein 398 2.1 NM_000925 PDHB pyruvate dehydrogenase (lipoamide) beta 2.0 NM_007187 WBP4 WW domain binding protein 4 (formin binding protein 21) 2.0 NM_006704 SGT1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) 1.9 NM_004888 ATP6G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G isoform 1 1.7 NM_013379 DPP7 dipeptidylpeptidase 7 8.6 NM_014762 DHCR24 24-dehydrocholesterol reductase 2.1 NM_032565 EBRP emopamil binding related protein, delta8-delta7 sterol isomerase related protein 2.5 NM_015533 DKFZP586B1621 DKFZP586B1621 protein 2.3 NM_003366 UQCRC2 ubiquinol-cytochrome c reductase core protein II 1.8 1382894.51 2.2 NM_014751 KIAA0429 metastasis suppressor 1 4.8 NM_014720 SLK SNF1 sucrose nonfermenting like kinase (yeast) 2.9 NM_006716 ASK activator of S phase kinase 1.8 U57623 FABP3 Human fatty acid binding protein FABP gene, complete cds. 9.8 NM_004282 BAG2 BCL2-associated athanogene 2 1.8 AF400074 SFTPB Homo sapiens surfactant, pulmonary-associated protein B (SFTPB) gene, complete cds. 2.1 NM_003130 SRI sorcin 1.9 NM_001540 HSPB1 heat shock 27kDa protein 1 2.7 NM_022170 WBSCR1 Williams-Beuren syndrome chromosome region 1 1.8 NM_001151 SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 6.9 AB007618 COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like 10.8 AJ330090 Homo sapiens genomic sequence surrounding NotI site, clone NR1-WB20R. 2.2 U90878 PDLIM1 PDZ and LIM domain 1 (elfin) 6.1 NM_020992 PDLIM1 PDZ and LIM domain 1 (elfin) 8.8 NM_006022 TSC22 transforming growth factor beta-stimulated protein TSC-22 1.9 BE615983 STUB1 STIP1 homology and U-Box containing protein 1 3.9 NM_032312 MGC11061 hypothetical protein MGC11061 1.3 NM_004332 BPHL biphenyl hydrolase-like (serine hydrolase; breast epithelial mucin-associated antigen) 1.7 NM_005346 HSPA1B heat shock 70kDa protein 1B 2.2 M59830 HSPA1B Human MHC class III HSP70-2 gene (HLA), complete cds. 4.4 NM_000786 CYP51 cytochrome P450, family 51, subfamily A, polypeptide 1 2.5 NM_006530 GAS41 glioma-amplified sequence-41 2.1 NM_032027 BBP beta-amyloid binding protein precursor 1.7 AK025140 FLJ32421 hypothetical protein FLJ32421 1.7 NM_003379 VIL2 villin 2 (ezrin) 2.3 NM_019000 FLJ20152 hypothetical protein FLJ20152 3.4 NM_001252 TNFSF7 tumor necrosis factor (ligand) superfamily, member 7 9.7 NM_024417 FDXR ferredoxin reductase 2.1 U76542 PYCS pyrroline-5-carboxylate synthetase (glutamate gamma-semialdehyde synthetase) 1.6 U03851 CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 1.9 NM_014178 HSPC156 syntaxin binding protein 6 (amisyn) -7.1 NM_006854 KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -2.3 NM_001439 EXTL2 exostoses (multiple)-like 2 -2.1 NM_013989 DIO2 deiodinase, iodothyronine, type II -4.8 NM_018153 TEM8 anthrax toxin receptor 1 -2.3 NM_012098 ANGPTL2 angiopoietin-like 2 -7.3 NM_000900 MGP matrix Gla protein -21.5 NM_004370 COL12A1 collagen, type XII, alpha 1 -10.3 NM_020411 GAGED2 G antigen, family D, 2 -26.8 NM_006818 AF1Q ALL1-fused gene from chromosome 1q -3.7 NM_006042 HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 -3.9 NM_018071 FLJ10357 -2.9 BI493312 TIRP TRIF-related adaptor molecule -1.9 AP003480 Homo sapiens genomic DNA, chromosome 8q23, clone: KB1970H2. -2.3 AK026977 MYH10 myosin, heavy polypeptide 10, non-muscle -4.2 NM_005576 LOXL1 lysyl oxidase-like 1 -4.7 NM_006417 MTAP44 interferon-induced protein 44 -7.0 NM_002192 INHBA inhibin, beta A (activin A, activin AB alpha polypeptide) -2.9 1446924.4 -6.0 BC007259 -4.7 NM_000358 TGFBI transforming growth factor, beta-induced, 68kDa -10.1 NM_001839 CNN3 calponin 3, acidic -2.7 NM_004899 BRE brain and reproductive organ-expressed (TNFRSF1A modulator) -2.3 NM_003528 H2BFQ histone 2, H2be -3.2 AK024362 LOC147650 hypothetical protein LOC147650 -3.5 AL110136 LOC440944 Homo sapiens mRNA; cDNA DKFZp564I112 (from clone DKFZp564I112). -2.3 NM_130467 PAGE-5 PAGE-5 protein -132.5 NM_005635 SSX1 synovial sarcoma, X breakpoint 1 -20.7 NM_003516 H2AFO histone 2, H2aa -2.4 NM_005367 MAGEA12 melanoma antigen, family A, 12 -6.6 NM_014185 MOG1 Homo sapiens RAN guanine nucleotide release factor (RANGNRF), mRNA. -2.6 NM_003254 TIMP1 tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor) -2.0 NM_024841 FLJ14213 hypothetical protein FLJ14213 -5.1 NM_005651 TDO2 tryptophan 2,3-dioxygenase -7.4 AB032957 KIAA1131 HECT domain containing 1 -1.6 NM_013390 TMEM2 transmembrane protein 2 -3.4 NM_002376 MARK3 MAP/microtubule affinity-regulating kinase 3 -1.9 NM_032041 NCALD neurocalcin delta -9.1 B: Cisplatin Gene bank Gene Gene name Fold accesion symbol difference number NM_005738 ARL4 ADP-ribosylation factor-like 4 -2.6 NM_020395 LOC57117 hypothetical nuclear factor SBBI22 -1.7 NM_020139 LOC56898 dehydrogenase/reductase (SDR family) member 6 -3.0 AB037752 SENP2 Start codon is not identified.; Homo sapiens mRNA for KIAA1331 protein, partial cds. -1.9 NM_001610 ACP2 acid phosphatase 2, lysosomal -3.3 AK024362 LOC147650 hypothetical protein LOC147650 -4.6 NM_001535 HRMT1L1 HMT1 hnRNP methyltransferase-like 1 (S. cerevisiae) -2.2 NM_002018 FLII flightless I homolog (Drosophila) -2.3 NM_022067 FLJ12707 chromosome 14 open reading frame 133 -1.7 NM_017976 FLJ10038 GA binding protein transcription factor, beta subunit 2, 47kDa -2.7 1446924.4 -5.7 NM_020411 GAGED2 G antigen, family D, 2 -16.0 BC007259 -4.4 AL110136 LOC440944 Homo sapiens mRNA; cDNA DKFZp564I112 (from clone DKFZp564I112). -2.5 NM_005635 SSX1 synovial sarcoma, X breakpoint 1 -12.9 NM_130467 PAGE-5 PAGE-5 protein -84.0 NM_005651 TDO2 tryptophan 2,3-dioxygenase -8.1 NM_024841 FLJ14213 hypothetical protein FLJ14213 -5.3 NM_006801 KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 -2.4 AB032957 KIAA1131 HECT domain containing 1 -1.6 NM_013390 TMEM2 transmembrane protein 2 -3.5 NM_032041 NCALD neurocalcin delta -9.3 NM_003516 H2AFO histone 2, H2aa -2.0 NM_003528 H2BFQ histone 2, H2be -3.6 NM_033027 AXUD1 AXIN1 up-regulated 1 -2.2 1049490.1 -2.7 AK026181 PHLDA1 pleckstrin homology-like domain, family A, member 1 -6.3 NM_003873 NRP1 neuropilin 1 -4.9 AB050468 LIG1 leucine-rich repeats and immunoglobulin-like domains 1 -4.5 NM_000153 GALC galactosylceramidase (Krabbe disease) -8.0 NM_002391 MDK midkine (neurite growth-promoting factor 2) -2.8 NM_013360 ZNF222 zinc finger protein 222 -3.0 AB020643 KIAA0836 glucuronyl C5-epimerase -3.4 AI557212 SKIL SKI-like -1.7 NM_013230 CD24 CD24 antigen (small cell lung carcinoma cluster 4 antigen) -5.6 NM_017432 PTOV1 prostate tumor overexpressed gene 1 -2.0 NM_016224 SNX9 sorting nexin 9 2.0 NM_003345 UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 1.6 NM_001236 CBR3 carbonyl reductase 3 3.3 NM_015415 DKFZP564B167 DKFZP564B167 protein 2.2 AK000596 HPCAL1 hippocalcin-like 1 2.6 NM_001280 CIRBP cold inducible RNA binding protein 2.1 NM_002906 RDX radixin 2.5 NM_000237 LPL lipoprotein lipase 13.7 NM_024703 FLJ22593 hypothetical protein FLJ10640 19.7 NM_005398 PPP1R3C protein phosphatase 1, regulatory (inhibitor) subunit 3C 3.3 NM_012425 RSU1 Ras suppressor protein 1 2.1 NM_080806 COL13A1 collagen, type XIII, alpha 1 7.6 NM_024061 MGC5521 vav-1 interacting Kruppel-like protein 3.3 NM_007274 HBACH brain acyl-CoA hydrolase 2.8 NM_013379 DPP7 dipeptidylpeptidase 7 11.7 NM_006054 RTN3 reticulon 3 2.0 NM_032565 EBRP emopamil binding related protein, delta8-delta7 sterol isomerase related protein 2.6 AJ131016 SCL Homo sapiens SCL gene locus. 1.8 NM_004526 MCM2 MCM2 minichromosome maintenance deficient 2, mitotin (S. cerevisiae) 2.3 NM_001667 ARL2 sorting nexin 15 2.8 NM_024084 TMEM223 transmembrane protein 223 5.4 AL832246 hnRNPA3 heterogeneous nuclear ribonucleoprotein A3 2.3 NM_005671 D8S2298E reproduction 8 1.9 NM_004494 HDGF hepatoma-derived growth factor (high-mobility group