IBANGS Conference Program Brief Program Monday, May 21 7 1.00 – 4.30 pm: Satellite Symposium 1 Sponsored by Neurad 7 2.20 pm: Break 11 4.45 – 6.30 pm: Satellite Symposium 2 16 Genes, Brain and Behavior 6.30 – 8.30 pm: Registration and welcome reception 16 8 am: Breakfast 17 2007 Society Annual Meeting 8.30 am – 10.00 am: Plenary Session 17 10 am: Coffee 17 10.30 am – 12.30 pm: Symposium 1 18 International Behavioural and Neural Genetics Society 12.30 pm: Lunch 22 May 21-25, 2007,Golden Tulip Hotel, Doorwerth, The Netherlands 2.00 – 4.00 pm: Symposium 2 23 4.00 pm: Break 26 4.30 – 6.00 pm: Outstanding Young Investigators Awardee Talks 27 Doorwerth, The Netherlands 7.00 pm: Dinner 29 Wednesday, May 23 30 8 am: Breakfast 30 Sponsored by: 8.45 – 10.45 am: Symposium 3 30 10.45 am: Coffee 33 National Institute on Alcohol Abuse and Alcoholism , National Institutes of 11.15 am: Distinguished Awardee lecture: Robert Williams 34 Health, USA 12.15 pm: Lunch 35 1.45 – 3.45 pm: Symposium 4 36 EXHIBITORS: 3.45 pm: Break 39 4.15 – 6.15 pm: Poster session 40 ViewPoint Behavior Technology http://viewpoint.fr/ 7.00 pm: Barbecue dinner 74 Noldus Information Technology BV http://www.noldus.com/ Friday, May 24 74 8 am: Breakfast 74 8.45 am: Local Organizing Committee plenary lecture: SDM Brown 74 10.15 am – 12.15 pm: Symposium 5 76 12:30pm- 7:00 pm: Social Program 79 7.00 pm: Dinner 79 Friday, May 25 80 8 am: Breakfast 80 Program Committee: 8.45 – 10.45 am: Symposium 6 80 10.45 am: Coffee 84 Andrew Holmes (Bethesda, USA; Chair) 11.15 am: Young Investigator Awardee lecture:Elissa Chesler 84 Dan Goldowitz (Memphis, USA) 12.15 pm: Lunch 85 Oliver Stork (Magdeburg, Germany) 1.45 – 3.45 pm: Symposium 7 85 Leo Schalkwyk (London, UK) 3.45 pm: Break 89 Helen Kamens (Portland, USA) 4.00 pm: Selected papers session: 89 6.00 pm: IBANGS business meeting; open to all members. 96 7.30 pm: Closing banquet 96 Local Organizing Committee: Leo Schalkwyk (London, UK) Sabine Spijker (Amsterdam, The Netherlands) Cathy Fernandes (Utrecht, The Netherlands) Guus Smit (Amsterdam, The Netherlands) Martien Kas (Utrecht, The Netherlands) 2 10.55 am: Bruno Van Swinderin 19 The Standard Matrix: A novel approach to exploring genetic effects on behavior in Monday, May 21 7 Drosophila 19 1.00 – 4.30 pm: Satellite Symposium 1 Sponsored by Neurad 7 11.20 am: Josh Dubnau 20 Alzheimer’s disease - new insights from animal models and molecular pathways, to Suppressor screening by selective breeding 20 be translated into human pathology. 7 11.45 am: Robert Williams 21 Chairs Thomas Bayer & Fred Van Leuven 7 Reverse Complex Trait Analysis: or what you can do with sequence data from 16 β β The mysteries of A amyloid: fibrillar–nonfibrillar, intracellular–extracellular, A 40– strains of mice 21 β A 42: where does it all lead to? 8 12.10 pm: General discussion 22 1.20 pm: Benoit Delatour 9 12.30 pm: Lunch 22 Behavioral phenotype of a new transgenic mouse model replicating cerebral 2.00 – 4.00 pm: Symposium 2 23 amyloidosis and neuronal loss of Alzheimer’s disease 9 Translational genetic approaches to the study of fear and anxiety 23 1.40 pm: Kathy Keyvani 10 Chairs Abraham Palmer & Andrew Holmes 23 Alzheimer's disease: effects of environmental enrichment 10 2.00 pm: Abraham Palmer (Travel Award) 23 2.00 pm: Thomas A. Bayer 11 Common and different genetic control of learned fear and innate anxiety-like Synaptic deficits correlate with neuron loss and changes in behaviour in the behavior in mice 23 APP/PS1ki mouse model 11 2.25 pm: Victoria Risbrough 24 2.20 pm: Break 11 Translational studies of CRF system contributions to anxiety 24 3.00 pm: Chris Janus 12 2.50 pm: Lukas Pezawas 25 Inducible tau mice 12 Epistasis of SERT & BDNF: A Complex Genetic Model of Depression 25 3.20 pm: Paul Lucassen 13 3.15 pm: Andrew Holmes 26 Increases in LTP and learning but not neurogenesis in young P301L tau mutant Exploring the genetic and neural basis of fear extinction using mouse models 26 mice. 13 3.40 pm: General discussion 26 3.40 pm: Katharina Schindowski 14 4.00 pm: Break 26 Alzheimer's disease-like cortical and hippocampal imbalance of Brain-Derived- 4.30 – 6.00 pm: Outstanding Young Investigators Awardee Talks 27 Neurotrophic-Factor and Nerve-Growth-Factor in a tau transgenic model 14 Chair John Crabbe 27 4.00 pm: Fred Van Leuven 15 4.30 pm: Anne Albrecht 27 Bigenic transgenic mice: amyloid and tau pathology are linked by GSK-3β 15 Expression of neuropeptide Y and somatostatin in fear conditioned mice 27 4.20 pm: General discussion 15 5.00 pm: Clarissa Parker 28 4.45 – 6.30 pm: Satellite Symposium 2 16 Genetics of basal plasma corticosterone levels in the LXS Recombinant Inbred Behavioral Phenotyping in the Home Cage: Methods and Tools 16 mouse strains 28 4.45 pm: Lucas P.J.J. Noldus 16 5.30 pm: Heidi Lesscher 29 Welcome and introduction 16 Amygdala PKC epsilon regulates corticotrophin releasing factor, anxiety-like 5:00 pm: Berry M. Spruijt 16 behavior and alcohol consumption 29 Back to the future: Behavioral testing in the home cage 16 7.00 pm: Dinner 29 5:15 pm: Maarten Loos 16 Genetic encoding of anxiety and impulsivity in inbred strains of mice 16 Wednesday, May 23 30 5.30 pm: Leonie de Visser 16 8 am: Breakfast 30 Anxiety measured and validated in the home cage 16 8.45 – 10.45 am: Symposium 3 30 5.45 pm: Pim Kuurman 16 Behavioural phenotyping for alterations in brain function 30 Mathematical modeling: from measurement data to phenogram 16 Chair Sabine Hölter-Koch 30 6:00 pm: Guus Smit, Amsterdam 16 8.45 am: Katharine Webb 30 Phenotyping at large: the Dutch Mouse Phenomics consortium 16 Identification of mutations affecting amphetamine-induced reward in zebrafish 30 6:15 Andrew Spink, Wageningen 16 9.10 am: Pat Nolan 31 Demonstration of new tools for behavioral phenotyping, with hands-on experience 16 Cloning and characterisation of novel mouse circadian mutants in ENU screens 31 6.30 – 8.30 pm: Registration and welcome reception 16 9.35 am: Silvia Mandillo 32 sponsored by Noldus Information Technology Inc. 16 Mice lacking the parkin associated receptor GPR37 show behavioral abnormalities Tuesday, May 22 17 linked to dopaminergic system alterations 32 8 am: Breakfast 17 10.00 am: Jan Deussing 33 8.30 am – 10.00 am: Plenary Session 17 CRH overexpression in the brain exerts antidepressant-like effects 33 8.45 am: Opening remarks: Tamara Phillips 17 10.25 am: General discussion 33 9.00 am: Presidential plenary lecture: CP Kyriacou 17 10.45 am: Coffee 33 Natural genetic variation in circadian behaviour 17 11.15 am: Distinguished Awardee lecture: Robert Williams 34 CP Kyriacou 17 introduced by Daniel Goldowitz 34 10 am: Coffee 17 Systems Genetics of Brain Structure and Function: A jigsaw puzzle 34 10.30 am – 12.30 pm: Symposium 1 18 12.15 pm: Lunch 35 Post genome genetic dissection of behavior, 18 1.45 – 3.45 pm: Symposium 4 36 Chair Josh Dubnau 18 COMT Val158Met: a uniquely human balanced polymorphism 36 10.30 am: Kristin Scott 18 Chair Mary-Anne Enoch, National Institute on Alcohol Abuse and Alcoholism, USA 36 Imaging taste in the Drosophila brain 18 1.45 pm: Mary-Anne Enoch 36 The influence of COMT genotype on anxiety and addiction 36 3 4 2.10 pm: Andreas Heinz 37 1.45 pm: John Cryan 85 COMT genotype effects on central processing of affective stimuli 37 In search of depressed mouse: Using genetically modified mice to understand 2.35 pm: Elizabeth Tunbridge 38 depression 85 The role of COMT in prefrontal function and its relevance to schizophrenia 38 2.10 pm: Stephanie Dulawa 86 3.00 pm: Ben J Baig, University 39 Genetic mechanisms underlying the behavioral response to chronic antidepressant Relationship of COMT variants to brain structure, function and risk of psychosis 39 treatment: insights from new mouse models 86 3.25 pm: General discussion 39 2.35 pm: Inga Neumann 87 3.45 pm: Break 39 Selection for high versus low anxiety: rat model for anxiety, depression and high 4.15 – 6.15 pm: Poster session 40 aggression 87 7.00 pm: Barbecue dinner 74 3.00 pm: John Quinn 88 Molecular genetics of human monoaminergic transporters: relevance to behavioral Friday, May 24 74 disorders and drug response 88 8 am: Breakfast 74 3.25 pm: General discussion 89 8.45 am: Local Organizing Committee plenary lecture: SDM Brown 74 3.45 pm: Break 89 introduced by Leo Schalkwyk 74 4.00 pm: Selected papers session: 89 The functional annotation of the mouse genome - the challenge of phenotyping 74 Chair Andrew Holmes 89 10.15 am – 12.15 pm: Symposium 5 76 4.00 pm: Lisa Tarantino 89 New insight in molecular mechanisms of synaptic plasticity and multiple memory Identification of an ENU-induced mutant that displays hyperactivity in a novel systems 76 environment, exaggerated responses to psychostimulants and a prolonged stress Chairs Melly Oitzl & Harm Krugers 76 response 89 10.15 am: Kamila Markram 76 4.15 pm: Igor Ponomarev 90 Distinct role of the polysialylated neural cell adhesion molecule (PSA-NCAM) in Alcohol-induced changes in global gene expression in a mouse model of binge cue and context fear conditioning 76 drinking 90 10.40 am: Oliver Stork 77 4.30 pm: Derrick Nehrenberg 91 Somatostatin: a novel molecular mechanisms of fear memory consolidation in Mice selectively bred for high aggression reproduce key features of emotional amygdala and hippocampus 77 dysregulation 91 11.05 am: Harm Krugers 78 4.45 pm: Aki Takahashi 92 Hormonal control of molecular mechanisms involved in learning and memory 78 Forward genetics approach toward complex traits using consomic mouse strains 11.30 am: Thomas Steckler 79 established from C57BL/6J and wild-derived MSM 92 Modulation of glutamatergic mechanisms in learning and memory - focus on 5.00 pm: Michael Parsons 93 metabotropic glutamate receptors 79 Candidate gene association studies for anxiety, activity and cognitive performance 11.55 am: General discussion 79 in mice 93 12:30pm- 7:00 pm: Social Program 79 5.15 pm: Annetrude de Mooij-van Malsen 94 visits to Burgers Zoo, Museum Kröller-Müller (or Arnhem station for those wishing to Genetic dissection of avoidance behavior and motor activity levels using go further afield).