Supporting Information

Supporting Information

Electronic Supplementary Material (ESI) for New Journal of Chemistry. This journal is © The Royal Society of Chemistry and the Centre National de la Recherche Scientifique 2018 Supporting Information Metal oxide nanoparticles Functionalized Sebacic Acid grafted PHEAM nanocarriers for enriched activity of Metronidazole against food borne bacteria: in vitro and in vivo study Murugesan Gowria, Kannan Suganyab, Nachimuthu Lathaa*, Marudhamuthu Muruganb, Mukhtar Ahmedc, Abdullah A. Alarfajd, Mariappan Rajane** aDepartment of Chemistry, Kandaswami Kandar’s College, Paramathi Velur, Namakkal District, Tamil Nadu 638182, India bDepartment of Microbial Technology, School of Biological Sciences, Madurai Kamaraj University, Madurai, Tamil Nadu 625021, India cDepartment of Zoology, College of Science, King Saud University, Riyadh 11451, Kingdom of Saudi Arabia dDepartment of Botany and Microbiology, College of Science, King Saud University, Riyadh 11451, Kingdom of Saudi Arabia eBiomaterials in Medicinal Chemistry Laboratory, Department of Natural Products Chemistry, School of Chemistry, Madurai Kamaraj University, Madurai, Tamil Nadu 625021, India Corresponding author *Nachimuthu Latha, Department of Chemistry, Kandaswami Kandar’s College, Paramathi Velur, Namakkal District, Tamil Nadu - 638182, India. Tel: +91 9487427667. Email: [email protected] **Mariappan Rajan, Biomaterials in Medicinal Chemistry Laboratory, Department of Natural Products Chemistry, School of Chemistry, Madurai Kamaraj University, Madurai - 625021, India. Tel: +91 9488014084; Email: [email protected] (Contacting author) Supplementatary figures Figure S1. EDX spectrum of ZnO/SA-g-PHEMA (A), MgO/SA-g-PHEMA (B), MgO-ZnO/SA- g-PHEMA (C), ZnO/SA-g-PHEMA-MTZ (D), MgO/SA-g-PHEMA-MTZ (E), MgO-ZnO/SA-g- PHEMA-MTZ (F). Figure S2(A-C). Encapsulation efficiency of ZnO/SA-g-PHEMA-MTZ (A), MgO/SA-g- PHEMA-MTZ (B), MgO-ZnO/SA-g-PHEMA-MTZ (C). Figure S3(A-D). In vitro drug release of ZnO/SA-g-PHEMA for the pH- 1.2, 2.5, 5.5, 7.4. Figure S4(A-D). In vitro drug release of MgO/SA-g-PHEMA for the pH- 1.2, 2.5, 5.5, 7.4. Figure S5(A-D). In vitro drug release of MgO-ZnO/SA-g-PHEMA for the pH- 1.2, 2.5, 5.5, 7.4..

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