Cambridge University Press 0521793513 - Diseases of the Nervous System: Clinical Neuroscience and Therapeutic Principles, Third Edition Edited by Arthur K. Asbury, Guy M. McKhann, W. Ian McDonald, Peter J. Goadsby and Justin C. McArthur Index More information Index Note: this is a complete two-volume index Note: page numbers in italics refer to figures and tables; ‘Fig.’ refers to illustrations in the plates section Abbreviations of conditions used in subheadings (without explanation): AD Alzheimer’s disease AIDS Acquired immune deficiency syndrome ALS Amyotrophic lateral sclerosis CJD Creutzfeldt–Jakob disease FTD Frontotemporal dementia HIV Human immunodeficiency virus HD Huntington’s disease PD Parkinson’s disease SIADH syndrome of inappropriate secretion of antidiuretic hormone A-fibres 873–4 abdominoperineal resection of carcinoma acetaminophen activation 875 846 migraine 1940 brain-derived nerve growth factor 884, abducens motoneurons 636 shingle pain 1678 885 abducens nerve acetazolamide sprouted 885, Fig. 58.12 fascicle lesions 650 acidification 1235 A2M genetic locus 5 middle ear disease 670 idiopathic intracranial hypertension A␣ fibres 874 palsy 649–51 2027 A␤ antibody passive transfer 1853–4 petrous bone infection 651 periodic paralysis 1201–2 A␤ fibres 874 abducens nucleus acetyl CoA 1210 AD 1844 abducens nerve palsy 649 acetylcholine formation in familial AD 1845 horizontal conjugate eye movements AD 256 see also amyloid 635, 636, 637 brain aging 198 A␤ immunization 1853–4 lesions 635 Lewy body dementia 273, 274 A␤ peptide 12, 215 oculomotor nerve neurons 647, 648 neuromuscular junction 1143, 1144 AD 255–6, 257, 258 abetalipoproteinemia 1139–40, 1882, olfactory deficit 604 clearance 229 1883 parasympathetic system 1341, 1342 degradation/clearance stimulation 262 abulia 1962 quantal release 1143–4 immunization against 262 acamprosate, alcoholism treatment 441, release at neuromuscular junction production blocking 262 1821 1143–4 see also A␤ amyloid plaques acanthocytosis 1882 swallowing 800 A␤42 acceleration, rotational in brain injury acetylcholine receptor (AChR) 1143, 1144, AD 1844, 1846 1799 1144–6 CSF levels 262 acetaldehyde 1820, 1821 antibody assay 1150–1 ABCC gene mutations 1412 acetaldehyde–protein adducts 1821 channel abnormalities 1145 973 © Cambridge University Press www.cambridge.org Cambridge University Press 0521793513 - Diseases of the Nervous System: Clinical Neuroscience and Therapeutic Principles, Third Edition Edited by Arthur K. Asbury, Guy M. McKhann, W. Ian McDonald, Peter J. Goadsby and Justin C. McArthur Index More information 974 Index acetylcholine receptor (cont.) onset 1673 infantile spasms 1240 clustering at neuromuscular junction optic neuritis 1674–5 obsessive–compulsive disorder 394 1145 acyclovir pituitary adenoma 859–60 deficiency 1155–7 herpes simplex encephalitis 1671 rapid stimulation test 864 myasthenia gravis 1148, 1520 herpes simplex meningitis 1664 secretion 854 acetylcholinesterase 1143, 1146 acyl-CoA dehydrogenase deficiency adrenoleukodystrophy 1138, 1882 end-plate deficiency 1160 short-chain 1221 neonatal 1633, 1913 achondroplasia very-long chain 1220 X-linked 1633–6, 1913 craniocervical junction anomaly 732 acyl-CoA oxidase deficiency 1913 adrenal function 1635, 2039 low back pain 763 acylcarnitines, long-chain 1219 animal model 1635 achromatopsia 627, 628 adamalysins 1511 bone marrow transplantation 1635–6 acid maltase deficiency 1208, 1217 addiction 431 clinical features 1633–4 acoustic neuroma definition 916 diagnosis 1635 auditory nerve degeneration 673 glutamate pathways 440 dietary therapy 1636 childhood 1449 Addison’s disease 1175, 2039 gene defect 1634–5 pain 940 Guillain–Barré syndrome 2039 imaging 1635, 1636 radiotherapy 1494 addressins 1595 pathology/pathogenesis 1635 surgery 674 adeno-associated virus vaccine against phenotypes 1634 acoustic reflex thresholds 666, 668 NR1 subunit 68 therapy 1635–6 acousticomotor system 663 adenosine adrenomyeloneuropathy 1138, 1633–4, acrodermatitis chronica atrophicans 1757 alcohol intoxication 1819 1635 acromegaly 858–9 cerebral blood flow regulation 1337–8 adrenal function 2039 glucose-GH suppression test 855, 859 peripheral sensitization 880 ataxia 1891 acrylamide neuropathy 1082–3, 1104 sleep promotion 819 bone marrow transplant actin 1163 adenosine diphosphate 1207 contraindication 1636 fibrous (f-actin) 90 muscle glycolytic defects 1211 adult T-cell leukemia 1710–11 ␣-actin gene 1171–2 adenosine triphosphate advanced sleep phase syndrome 825 action potentials hydrolysis 1207 Advanced Trauma Life Support (ATLS) bursts in nervous system lesions 897 muscle fatigue 1209 1796 compound muscle 1111, 1157, 1159 adenosyl cobalamin system 2046 aerobic fitness 1210 orthodromic 877 adhalin deficiency 1167 affective disorders see mood disorders propagated and potassium flow 1195 adhesion molecules age-related changes propagation to spinal cord 878 bacterial meningitis 1733 accumulation 242 saltatory conduction 1077, 1078, 1595 viral infection 1655 intrinsic 240–2 fast 876, Fig. 58.5 adjustment disorders 364 molecular mechanisms 239–42 actions, meaningful 472 adoption studies 15 ageusia 614 activation-flow coupling (AFC) 131, 132 adrenal disease, neurological thalamus injury 615 spatial extent 136 complications 2038–40 aggression activator-complex protein-1 (AP-1) 1436 adrenal hormone replacement therapy attention deficit hyperactivity disorder activities of daily living 1635 423 AD 254 adrenal insufficiency periaqueductal grey 890 dementia 245 hypercalcemia 2004 aggressive outbursts 1283, 1284 acupuncture hyperkalemia 2010–11 aging dystonia 543 secondary 862 alpha frequency 238 pain control 917 SIADH differential diagnosis 868 Alzheimer’s disease 253 acute disseminated encephalitis 1529 suspected secondary 864 anatomical changes 237–9 acute disseminated encephalomyelitis adrenalectomy, bilateral 860 apoptosis 241 ␣ 1514, 1624, 1673–5 2-adrenergic agonists 913 brain 237–8 imaging 1673–4 ␤-adrenergic receptor 26 caloric restriction 241 management 1674 ␣-adrenoceptors, cerebral circulation cellular basis 241 multiple sclerosis differential diagnosis 1343 cerebral blood flow 238 1624 adrenocorticotrophic hormone (ACTH) dementia 237–46, 242–3 © Cambridge University Press www.cambridge.org Cambridge University Press 0521793513 - Diseases of the Nervous System: Clinical Neuroscience and Therapeutic Principles, Third Edition Edited by Arthur K. Asbury, Guy M. McKhann, W. Ian McDonald, Peter J. Goadsby and Justin C. McArthur Index More information Index 975 risk factor 246 albinism, optic chiasm disorders 625 antisocial personality disorder electroencephalogram 238 albuterol in facioscapulohumeral relationship 1820 estrogens 242 muscular dystrophy 1169, 1172 central pontine myelinolysis 1823 focal temporal slowing 238 alcohol/alcohol abuse 1814 disulfiram sensory–motor genetic basis 243 addiction 440–1 polyneuropathy 1102 neural growth factors 241–2 acute mechanisms 442 dopamine 440 neurodegeneration 210–11 autonomic dysfunction 787 epidemiology 1814 neurotransmitter function 238–9 binge drinking 1817, 1824 ethanol resistance 1815 olfactory dysfunction 600, 603 cerebellar degeneration 1823 ethanol tolerance 1815 penetrating artery disease syndromes dopamine levels in nucleus acumbens genetic risk 1820 1356 432 genetics 1820 physiological changes 237–9 drug abuse 1834, 1835 Marchiafava–Bignami disease 1823 aging population 3 endorphins 440 treatment 441, 1820–1 agnosia, visual associated 628–9 epidemiology 1814 see also fetal alcohol syndrome agraphia 321 epilepsy 1255 aldolase A deficiency 1217 agrin 1145 essential tremor 518 aldosterone 2011 AIDS hypomagnesemia 2008 ALDP protein 1634 cytomegalovirus polyradiculitis intoxication 438, 1814–16 alertness 294 1085 benign paroxysmal positional vertigo Alexander disease 1642–4 dementia complex 1690–6 differential diagnosis 687 alexia 324 epidemic 3, 4, 123 severe 1815–16 primary reading epilepsy 1258 epidemiology 1683 intraneural injection for multiple algal blooms 1809, 1810 gracile tract degeneration 1082 sclerosis 1625 alien limb phenomenon, corticobasal neurological manifestations 123 kinetic tremor 519 degeneration 495–6 orphans 3 level of response (LR) 1820 ALK1 gene 2075 pandemic 1685 neurotoxicity 1814–24 allelic association 19, 20 peripheral neuropathy 1081 olfaction 599 allelic heterogeneity 14–15 sensory neuropathy 1093 opiate mechanisms in reward 440 allesthesia 332 vacuolar myelopathies 722 optic neuropathy 624 testing 334 see also HIV infection pharyngeal muscle tone suppression allokinesia testing 334 air emboli 1944–5 822 allopurinol, azathioprine interaction 1532 air travel 4 reward 433 Alpers disease 1919 airway patency, sleep 821 stroke 1943 alpha beta-crystalline 1643 akathisia 2045 primary prevention 1416 alpha frequency, aging 238 akinesia 333 tolerance 1815 Alport syndrome 672 corticobasal degeneration 495 withdrawal 433, 438 alprostadil 848 directional 333 delirium tremens 517 altered peptide ligands (APLs) 1508 hemispatial 333 nightmares 827 immunomodulation 1543 liver transplantation 1976 NMDA transmission 441 alternative therapies pathophysiology 336–7 REM sleep behaviour disorder 828 cerebral palsy 577 akinetic mutism seizures 440 dystonia 543 attention 293 syndrome 1816–17 pain control 917 awakeness 293 alcohol dehydrogenase (ADH) 1820 aluminium cingulate gyri 337 alcoholic blackouts 1815 accumulation 241, 1996 consciousness 295, 296 alcoholic dementia 1823 intoxication 1998 frontal lobes 337 alcoholic flush reaction 1820 serum levels 1996 medial thalamus 337 alcoholic myopathy 1824 alveolar