1475 HIV outbreak of Ratodero, Pakistan requires urgent concrete measures to avoid future outbreaks Naeem Mubarak1, Irshad Hussain2, Sarwat Ali Raja3, Tahir Mehmood Khan4, Che Suraya Zin5 Dear Editor, Table: Age/Gender Wise Break Up of HIV patients of Ratodero, Larkana.3 The outbreak of Ratodero, local scenario Age Group Male Female Ratodero belongs to district Larkana, Sindh. The reported 0 to 1 Years 54 42 outbreak of HIV continues to escalate. The official number 13 Months to 5 years 407 232 of confirmed HIV cases has been summarized in Table.1 06-12 Years 94 72 The outbreak is unprecedented since it involved 80% Adults 59 172 children. Previously there were1200 HIV cases of children c. Develop an early warning system through effective in whole Pakistan. In the wake of this outbreak, Sindh surveillance. Health Care Commission (SHCC) sealed 147 clinics and blood transfusion centres in Larkana and more than 600 d.Check the menace of quackery (the major contributor clinics were issued warning on questionable practices.2,3 in spread of the virus). With the grievous health crisis looming over Sindh, a WHO e. Educate the masses on risk factors, consequences of team classified the outbreak level as Grade-II emergency spread and highly objectionable practices of using and provided technical assistance.4 un-necessary injections and intravenous drips through The outbreak has raised serious apprehensions and the national level awareness campaigns. authorities must take concrete measures on the three aspects of the outbreak: The outbreak of Kot-Imrana, Punjab The outbreak of Ratodero is similar in many ways to the 1.To offer optimal healthcare including provision of previously reported HIV outbreak in Kot-Imrana.5 The psycho-social support,and procurement of medicines factors responsible for these outbreaks are common, for and diagnostic kits. This is extremely important as the instance misuse of syringes by quack, drug addicts, stocks of medicines and screening kits ran short.Thus, multiple use of razors at barbers' shops, infected sex it is high time for planning to involve international workers, improper disposal of hospital wastes and limited organizations to sustain it. surveillance. 2.There is a dire need to extend the current facilities to an optimal number which may respond to the huge Regional scenario influx of patients. There are only 7 HIV treatment facilities In the region, India and Cambodia have demonstrated a working all over Sindh (mostly in cities). promising decrease in the number of new registered cases 3.Local and national AIDS Control Programmes, Blood through effective policy making. Contrary, in Pakistan,there Banks and SHCC need to work in coordination to: is a 57% increase in the new cases of HIV (2010-18), the highest rise in the new cases of HIV in Asia.6 a.Curb the unsafe transfusion, especially through These outbreaks are just the tip of the iceberg. Experts unregistered blood banks. believe, if vigorous actions would not be taken, Pakistan b.Provide interventions to stop spread from potential could face serious outbreaks in future for which hotspots i.e. drug users, sex workers, transgenders consequences could be unimaginable. and barbers' shops. Disclaimer: The part of this manuscript was uploaded on 1,3Lahore Medical Dental College, University of Health Sciences, Lahore, Punjab, research gate for public awareness and will be updated Pakistan; 2Department of Pharmacy, Shaheed Mohtarma Benazir Bhutto Medical University, Larkana, Sindh, Pakistan; 4Institute of Pharmaceutical Science, per publication in journal. University of Veterinary and Animal Sciences, Lahore, Punjab, Pakistan; Conflict of Interest: None. 5Kulliyyah of Pharmacy, International Islamic University Malaysia Funding Sources: None. Correspondence: Irshad Hussain. e-mail: [email protected] Vol. 70, No. 8, August 2020 1476 N. Mubarak, I. Hussain, S.A. Raja et al. References 4. Bhatti MW, WHO declared HIV outbreak in Larkana as grade 2 emergency. The International News: https://www.thenews.com.pk/ 1. National AIDS Control Program, Govt of Pakistan. HIV/AIDS Outbreak latest/ 481688-who-declares-hiv-outbreak-in-larkana-as-grade-2- Updates, Ratodero, Larkana, Sindh, Pakistan. accessed at emergency (Date Accessed 20th January 2020). https://www.nacp.gov.pk/ (Date accessed 21st December, 2019). 5. Wahid B. An update on the severe outbreak of HIV in KotImrana, 2. Zaid M, Ali M, Afzal MS. HIV outbreaks in Pakistan. The Lancet HIV. Pakistan. The Lancet Infectious Diseases. 2019;19:241. 2019 June 13th (Date Accessed 24th December 2019). 6. Country progress report Pakistan (2018). http://www.unaids.org/ 3. https://dailytimes.com.pk/488053/1132-hiv-positive-cases- sites/ default/files/country/documents/ PAK_2018_ detected-in-last-six-months/ (Date Accessed 20th January 2020). countryreport.pdf. (Date Accessed 20th January 2020). https://doi.org/10.5455/JPMA.57221 J Pak Med Assoc.