Flea and Tick Control Products a Product Manufacturer Active Ingredient(s) Parasite b Minimum Route of Age/Weight Administration Dogs Advantage Bayer Animal Health Imidacloprid Fleas 7 weeks Topical Advantage Multi for Dogs Bayer Animal Health Imidacloprid, moxidectin Fleas 7 weeks/3 lb Topical Capstar Novartis Animal Health Nitenpyram Fleas 4 weeks/2 lb Tablet Comfortis Eli Lilly and Company Spinosad Fleas 14 weeks Chewable tablet Frontline Plus for Dogs Merial Fipronil, S-methoprene Fleas and ticks 8 weeks Topical Frontline Spray Merial Fipronil Fleas and ticks 8 weeks Spray Frontline Top Spot for Dogs Merial Fipronil Fleas and ticks 8 weeks Topical K9 Advantix Bayer Animal Health Imidacloprid, permethrin Fleas and ticks 7 weeks Topical Program Flavor Tabs Novartis Animal Health Lufenuron Fleas 4 weeks Tablet ProMeris for Dogs Fort Dodge Animal Health Metaflumizone, amitraz Fleas and ticks 8 weeks Topical Proticall Insecticide Schering-Plough Permethrin Fleas and ticks 4 weeks Topical for Dogs Animal Health Revolution Pfizer Animal Health Selamectin Fleas and one tick 6 weeks Topical Sentinel Flavor Tabs Novartis Animal Health Milbemycin oxime, Fleas 4 weeks/2 lb Tablet lufenuron Vectra 3D Summit VetPharm Dinotefuran, permethrin, Fleas and ticks 7 weeks Topical pyriproxyfen Virbac Long-Acting Virbac Animal Health Permethrin, pyriproxyfen Fleas and ticks 6 months Spray KnockOut Spray Virbac Pyrethrin Dip Virbac Animal Health Pyrethrins, piperonyl Fleas and ticks 12 weeks Dip butoxide, N-octyl bicycloheptene dicarboximide, dipropyl isocinchomeronate Cats Advantage Bayer Animal Health Imidacloprid Fleas 8 weeks Topical Advantage Multi for Cats Bayer Animal Health Imidacloprid, moxidectin Fleas 9 weeks/2 lb Topical Capstar Novartis Animal Health Nitenpyram Fleas 4 weeks/2 lb Tablet Frontline Plus for Cats Merial Fipronil, S-methoprene Fleas and ticks 8 weeks Topical Frontline Spray Merial Fipronil Fleas and ticks 8 weeks Spray Frontline Top Spot for Cats Merial Fipronil Fleas and ticks 8 weeks Topical Program Novartis Animal Health Lufenuron Fleas 4 weeks (tablet), Tablet, 6 weeks suspension (suspension or injectable and injectable) ProMeris for Cats Fort Dodge Animal Health Metaflumizone Fleas 8 weeks Topical 8 Revolution Pfizer Animal Health Selamectin Fleas 8 weeks Topical 0 0 2 Vectra Summit VetPharm Dinotefuran, pyriproxyfen Fleas 8 weeks Topical e n u J / Virbac Pyrethrin Dip Virbac Animal Health Pyrethrins, piperonyl Fleas and ticks 12 weeks Dip M U R butoxide, N-octyl O F Y bicycloheptene R A N I dicarboximide, dipropyl R E T isocinchomeronate E V aSee the product label for information on the specific flea stage affected. bSome products also are used in the control of parasites not covered in this article (e.g., mosquitoes, helminths, heartworm, mites, lice, etc.)..