PDF Output of CLIC (clustering by inferred co-expression) Dataset: Num of genes in input gene set: 65 Total number of genes: 16493 CLIC PDF output has three sections: 1) Overview of Co-Expression Modules (CEMs) Heatmap shows pairwise correlations between all genes in the input query gene set. Red lines shows the partition of input genes into CEMs, ordered by CEM strength. Each row shows one gene, and the brightness of squares indicates its correlations with other genes. Gene symbols are shown at left side and on the top of the heatmap. 2) Details of each CEM and its expansion CEM+ Top panel shows the posterior selection probability (dataset weights) for top GEO series datasets. Bottom panel shows the CEM genes (blue rows) as well as expanded CEM+ genes (green rows). Each column is one GEO series dataset, sorted by their posterior probability of being selected. The brightness of squares indicates the gene's correlations with CEM genes in the corresponding dataset. CEM+ includes genes that co-express with CEM genes in high-weight datasets, measured by LLR score. 3) Details of each GEO series dataset and its expression profile: Top panel shows the detailed information (e.g. title, summary) for the GEO series dataset. Bottom panel shows the background distribution and the expression profile for CEM genes in this dataset. Overview of Co-Expression Modules (CEMs) with Dataset Weighting Scale of average Pearson correlations Num of Genes in Query Geneset: 65. Num of CEMs: 1. 0.0 0.2 0.4 0.6 0.8 1.0 Bub1 Birc5 Sgol1 Nuf2 Zwilch Bub1b Kntc1 Ndc80 Cenpk Spc24 Cenph Sgol2 Ercc6l Spag5 Incenp Nek2 Cenpn Cenpu Cenpw Apitd1 Casc5 Cenpm Nup107 Nup85 Nup133 Nup43 Nde1 Smc1a Cenpc1 Nudcd2 Cenpt Cenpo Dctn3 Dync1i1 Stra13 Tex14 Seh1l Knstrn Dynlt3 Itgb3bp Sept6 Pinx1 Ndel1 Sept2 Zwint Ahctf1 Dync1li1 Tpr Trp53bp1 Clasp1 Bod1 Csnk1a1 Cenpv Kif2b Clasp2 Zw10 Kif2c Champ1 Ss18l1 Sept7 Hjurp Rangap1 Mad1l1 Bub3 Spc25 Bub1 Birc5 Sgol1 Nuf2 Zwilch Bub1b Kntc1 Ndc80 Cenpk Spc24 Cenph Sgol2 Ercc6l Spag5 Incenp Nek2 CEM 1 (674 datasets) Cenpn Cenpu Cenpw Apitd1 Casc5 Cenpm Nup107 Nup85 Nup133 Nup43 Nde1 Smc1a Cenpc1 Nudcd2 Cenpt Cenpo Dctn3 Dync1i1 Stra13 Tex14 Seh1l Knstrn Dynlt3 Itgb3bp Sept6 Pinx1 Ndel1 Sept2 Zwint Ahctf1 Dync1li1 Tpr Trp53bp1 Singletons Clasp1 Bod1 Csnk1a1 Cenpv Kif2b Clasp2 Zw10 Kif2c Champ1 Ss18l1 Sept7 Hjurp Rangap1 Mad1l1 Bub3 Spc25 Symbol Num ofCEMGenes:32.Predicted522.SelectedDatasets:674.Strength:326.4 CEM 1,Geneset"[G]condensedchromosomekinetochore",Page1 Mis18bp1 Nudcd2 Nusap1 Shcbp1 Cenpc1 Nup133 Nup107 Cenpm Cenpw Smc1a Incenp Zwilch Cenpo Apitd1 Cenpu Cenpn Cenph Bub1b Ccnb2 Ncaph Ncapg Nup43 Nup85 Cenpk Ercc6l Cdca5 Rad51 Kif20a Ccna2 Spag5 Ndc80 Casc5 Spc24 Aurkb Aurka Cenpt Cenpi Kntc1 Sgol2 Sgol1 Birc5 Bub1 Kif11 Cdk1 Nde1 Nek2 Tpx2 Melk Nuf2 Pbk 0.0 1.0 GSE20954 [14] GSE57543 [6] GSE40513 [6] Only showingfirst200datasets-Seetxtoutputforfulldetails. GSE38031 [8] GSE16874 [12] GSE17794 [44] GSE31028 [6] GSE12454 [13] GSE54215 [13] GSE6957 [12] GSE12498 [12] GSE17266 [59] GSE54490 [12] GSE27605 [8] GSE38257 [14] GSE17796 [39] GSE51075 [12] GSE29241 [6] GSE51385 [8] GSE15741 [6] GSE48397 [10] GSE13611 [8] GSE39449 [6] GSE27114 [6] GSE6875 [8] GSE23502 [8] GSE20100 [15] GSE32386 [13] GSE15326 [10] GSE12993 [6] GSE18135 [18] GSE44260 [10] GSE6837 [8] GSE6689 [12] GSE13873 [27] GSE17316 [12] GSE51628 [15] GSE33308 [10] GSE51883 [30] GSE13693 [9] GSE38538 [6] GSE9247 [15] GSE46797 [6] GSE48382 [10] GSE44175 [18] GSE51243 [7] GSE34324 [12] GSE23925 [6] GSE19004 [9] GSE20696 [8] GSE48204 [6] GSE46209 [21] GSE16675 [72] GSE9763 [20] GSE28093 [6] GSE4694 [6] GSE28457 [24] GSE9287 [8] GSE50813 [24] GSE21224 [16] GSE35366 [78] GSE15303 [11] GSE52474 [154] GSE39621 [51] GSE13692 [8] GSE23845 [15] GSE7875 [16] GSE7348 [6] GSE10525 [18] GSE21491 [9] GSE16110 [16] GSE15872 [18] GSE15580 [14] GSE18115 [8] GSE54653 [6] GSE7020 [8] GSE53916 [6] GSE44101 [6] GSE28621 [21] GSE8025 [21] GSE21299 [12] GSE24628 [16] GSE38831 [7] GSE19925 [6] GSE15267 [8] GSE13225 [6] GSE31313 [22] GSE21900 [12] GSE8488 [15] GSE39984 [18] GSE15121 [6] GSE39082 [6] GSE22824 [24] GSE4260 [6] GSE46185 [6] GSE14769 [24] GSE8678 [6] GSE20302 [12] GSE12881 [6] GSE19436 [8] GSE29318 [9] GSE46090 [12] GSE39034 [9] GSE21309 [9] GSE30160 [6] GSE46091 [8] GSE21716 [28] GSE30962 [16] GSE30485 [15] GSE39469 [6] GSE22180 [60] GSE21568 [12] GSE51483 [45] GSE33471 [12] GSE15610 [12] GSE7657 [12] GSE21278 [48] GSE17096 [20] GSE32598 [11] GSE26616 [6] GSE18660 [10] GSE7694 [12] GSE17097 [20] GSE8660 [6] GSE20500 [6] GSE26355 [6] GSE19885 [9] GSE30192 [6] GSE24512 [29] GSE14012 [24] GSE40856 [8] GSE51608 [6] GSE46242 [12] GSE8039 [32] GSE18460 [16] GSE17509 [57] GSE5041 [8] GSE35593 [6] GSE45051 [18] GSE30745 [12] GSE24210 [16] GSE58296 [9] GSE31359 [8] GSE31598 [12] GSE7705 [10] GSE11759 [6] GSE20426 [35] GSE22005 [23] GSE13874 [14] GSE13408 [14] GSE48203 [9] GSE27786 [20] GSE45895 [27] GSE15155 [12] CEM+ CEM GSE24121 [9] GSE47959 [8] GSE4535 [6] GSE29632 [42] GSE14753 [6] GSE53951 [10] 0.0 GSE13302 [30] GSE14024 [12] GSE13493 [6] Scale ofaveragePearsoncorrelations GSE15324 [8] GSE18534 [15] GSE45222 [27] GSE36814 [20] GSE20620 [22] GSE8156 [6] 0.2 GSE10176 [6] GSE26290 [12] GSE7460 [52] GSE13149 [25] GSE45820 [6] GSE12465 [14] GSE21379 [10] GSE22124 [18] GSE21393 [6] 0.4 GSE11358 [8] GSE16992 [48] GSE45465 [39] GSE14406 [54] GSE13635 [6] GSE28417 [12] GSE32330 [12] GSE17745 [6] GSE15069 [15] 0.6 GSE5309 [7] GSE22935 [24] GSE4671 [28] GSE1435 [27] GSE32277 [33] GSE18993 [13] GSE4768 [18] GSE41342 [26] GSE16454 [24] 0.8 GSE6065 [100] GSE39897 [36] GSE48790 [8] GSE27848 [16] Score 668.25 673.55 675.34 675.47 676.98 677.63 683.06 683.80 685.40 690.19 691.05 692.38 700.01 715.15 719.92 729.18 737.56 740.92 1.0 Notes Symbol Num ofCEMGenes:32.Predicted522.SelectedDatasets:674.Strength:326.4 CEM 1,Geneset"[G]condensedchromosomekinetochore",Page2 Arhgap11a Rad51ap1 Depdc1a Racgap1 Ncapg2 Ncapd2 Ckap2l Cenpp Kif18b Cenpe Cdca2 Cdc45 Ckap2 Cep55 Ube2c Cdc20 Cdca8 Esco2 Fbxo5 Fignl1 Gmnn Mcm5 Cenpf Gins1 Brca1 Mki67 Prim1 Asf1b Aspm Spdl1 Espl1 Uhrf1 Rrm1 Cdc6 Kif22 Exo1 Ska3 Dbf4 Anln Prc1 Rfc5 Rfc4 Ect2 Pole Plk1 Plk4 Lig1 Kif4 Tk1 Stil 0.0 1.0 GSE20954 [14] GSE57543 [6] GSE40513 [6] Only showingfirst200datasets-Seetxtoutputforfulldetails. GSE38031 [8] GSE16874 [12] GSE17794 [44] GSE31028 [6] GSE12454 [13] GSE54215 [13] GSE6957 [12] GSE12498 [12] GSE17266 [59] GSE54490 [12] GSE27605 [8] GSE38257 [14] GSE17796 [39] GSE51075 [12] GSE29241 [6] GSE51385 [8] GSE15741 [6] GSE48397 [10] GSE13611 [8] GSE39449 [6] GSE27114 [6] GSE6875 [8] GSE23502 [8] GSE20100 [15] GSE32386 [13] GSE15326 [10] GSE12993 [6] GSE18135 [18] GSE44260 [10] GSE6837 [8] GSE6689 [12] GSE13873 [27] GSE17316 [12] GSE51628 [15] GSE33308 [10] GSE51883 [30] GSE13693 [9] GSE38538 [6] GSE9247 [15] GSE46797 [6] GSE48382 [10] GSE44175 [18] GSE51243 [7] GSE34324 [12] GSE23925 [6] GSE19004 [9] GSE20696 [8] GSE48204 [6] GSE46209 [21] GSE16675 [72] GSE9763 [20] GSE28093 [6] GSE4694 [6] GSE28457 [24] GSE9287 [8] GSE50813 [24] GSE21224 [16] GSE35366 [78] GSE15303 [11] GSE52474 [154] GSE39621 [51] GSE13692 [8] GSE23845 [15] GSE7875 [16] GSE7348 [6] GSE10525 [18] GSE21491 [9] GSE16110 [16] GSE15872 [18] GSE15580 [14] GSE18115 [8] GSE54653 [6] GSE7020 [8] GSE53916 [6] GSE44101 [6] GSE28621 [21] GSE8025 [21] GSE21299 [12] GSE24628 [16] GSE38831 [7] GSE19925 [6] GSE15267 [8] GSE13225 [6] GSE31313 [22] GSE21900 [12] GSE8488 [15] GSE39984 [18] GSE15121 [6] GSE39082 [6] GSE22824 [24] GSE4260 [6] GSE46185 [6] GSE14769 [24] GSE8678 [6] GSE20302 [12] GSE12881 [6] GSE19436 [8] GSE29318 [9] GSE46090 [12] GSE39034 [9] GSE21309 [9] GSE30160 [6] GSE46091 [8] GSE21716 [28] GSE30962 [16] GSE30485 [15] GSE39469 [6] GSE22180 [60] GSE21568 [12] GSE51483 [45] GSE33471 [12] GSE15610 [12] GSE7657 [12] GSE21278 [48] GSE17096 [20] GSE32598 [11] GSE26616 [6] GSE18660 [10] GSE7694 [12] GSE17097 [20] GSE8660 [6] GSE20500 [6] GSE26355 [6] GSE19885 [9] GSE30192 [6] GSE24512 [29] GSE14012 [24] GSE40856 [8] GSE51608 [6] GSE46242 [12] GSE8039 [32] GSE18460 [16] GSE17509 [57] GSE5041 [8] GSE35593 [6] GSE45051 [18] GSE30745 [12] GSE24210 [16] GSE58296 [9] GSE31359 [8] GSE31598 [12] GSE7705 [10] GSE11759 [6] GSE20426 [35] GSE22005 [23] GSE13874 [14] GSE13408 [14] GSE48203 [9] GSE27786 [20] GSE45895 [27] GSE15155 [12] CEM+ CEM GSE24121 [9] GSE47959 [8] GSE4535 [6] GSE29632 [42] GSE14753 [6] GSE53951 [10] 0.0 GSE13302 [30] GSE14024 [12] GSE13493 [6] Scale ofaveragePearsoncorrelations GSE15324 [8] GSE18534 [15] GSE45222 [27] GSE36814 [20] GSE20620 [22] GSE8156 [6] 0.2 GSE10176 [6] GSE26290 [12] GSE7460 [52] GSE13149 [25] GSE45820 [6] GSE12465 [14] GSE21379 [10] GSE22124 [18] GSE21393 [6] 0.4 GSE11358 [8] GSE16992 [48] GSE45465 [39] GSE14406 [54] GSE13635 [6] GSE28417 [12] GSE32330 [12] GSE17745 [6] GSE15069 [15] 0.6 GSE5309 [7] GSE22935 [24] GSE4671 [28] GSE1435 [27] GSE32277 [33] GSE18993 [13] GSE4768 [18] GSE41342 [26] GSE16454 [24] 0.8 GSE6065 [100] GSE39897 [36] GSE48790 [8] GSE27848 [16] Score 565.24 572.27 574.37 575.55 578.98 581.01 581.42 582.22 583.41 584.63 585.34 585.47 585.58 585.70 588.96 589.13 591.57 593.67 595.04 596.25 598.99 600.68 603.27 605.21 606.70 608.07 608.96 609.18 609.58 613.84 617.87 619.52 623.25 625.01 626.25 631.09 633.36 633.58 634.66 641.06 641.69 646.33 647.81 651.13 651.77 656.24 660.82 661.19 662.93 663.59 1.0 Notes 4930579G24Rik Symbol Num ofCEMGenes:32.Predicted522.SelectedDatasets:674.Strength:326.4 CEM 1,Geneset"[G]condensedchromosomekinetochore",Page3 BC055324 Depdc1b Mms22l Rad54b Topbp1 Cdc25c Parpbp Wdhd1 Iqgap3 Cenpq Chtf18