Table 2. Annotation of G. thermodenitrificans NG80-2 genome Gene ID Gene Gene product COG functional category name GT0001 dnaA DnaA COG0592, Replication, recombination and repair GT0002 gt2 DNA polymerase III, beta subunit COG0592, Replication, recombination and repair GT0003 gt3 Conserved hypothetical protein COG2501, Function unknown GT0004 recF RecF COG1195, Replication, recombination and repair GT0005 gt5 DNA gyrase subunit B COG0187, Replication, recombination and repair GT0006 gt6 DNA gyrase subunit A COG0188, Replication, recombination and repair GT0007 gt7 Conserved hypothetical protein COG2206, Signal transduction mechanism GT0008 yaaC YaaC GT0009 guaB Inosine-monophosphate dehydrogenase COG0516, Nucleotide transport and metabolism GT0010 gt10 D-alanine carboxypeptidase COG1686, Cell wall/membrane biogenesis GT0011 gt11 Pyridoxine biosynthesis protein COG0214, Coenzyme transport and metabolism GT0012 gt12 Glutamine amidotransferase Sno family COG0311, Coenzyme transport and metabolism GT0013 gt13 Seryl-tRNA synthetase COG0172, Translation GT0014 gt14 Spore peptidoglycan hydrolase, N-acetylglucosaminidase COG3858, General function prediction only GT0015 gt15 Cytosine deaminase COG0590, Nucleotide transport and metabolism GT0016 dnaZX DnaZX COG2812, Replication, recombination and repair GT0017 gt17 Conserved hypothetical protein COG0718, Function unknown GT0018 recR RecR COG0353, Replication, recombination and repair GT0019 gt19 Hypothetical cytosolic protein Gene ID Gene Gene product COG functional category name GT0020 gt20 Inhibitor of the pro-sigma K processing machinery GT0021 csfB CsfB GT0022 gt22 Similar to lysine decarboxylase COG1982, Amino acid transport and metabolism GT0023 tmk Thymidylate kinase COG0125, Nucleotide transport and metabolism GT0024 gt24 DNA polymerase III delta subunit COG0470, Replication, recombination and repair GT0025 gt25 Signal peptidase II COG1774, Function unknown GT0026 gt26 Conserved hypothetical protein COG4467, Function unknown GT0027 gt27 Methyltransferase COG4123, General function prediction only GT0028 gt28 Corrin/porphyrin methyltransferase COG0313, General function prediction only GT0029 gt29 Transition state regulator COG2002, Transcription GT0030 gt30 Methionine-tRNA ligase/methionyl-tRNA synthetase COG0143, Translation GT0031 gt31 Deoxyribonuclease TatD family COG0084, Replication, recombination and repair GT0032 gt32 Conserved hypothetical protein COG3583, Function unknown GT0033 gt33 Unknown GT0034 gt34 Ribonuclease M5 COG1658, Replication, recombination and repair GT0035 gt35 Dimethyladenosine transferase COG0030, Translation GT0036 yabG Sporulation-specific protease YabG GT0037 gt37 Conserved hypothetical protein COG4466, Function unknown GT0038 gt38 Small acid-soluble spore protein, minoralpha/beta-type SASP GT0039 gt39 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase COG1947, Lipid transport and metabolism GT0040 gt40 Transcriptional regulator COG0503, Nucleotide transport and metabolism Gene ID Gene Gene product COG functional category name GT0041 gt41 Translation initiation inhibitor COG0251, Translation GT0042 gt42 Stage V sporulation protein G COG2088, Cell wall/membrane biogenesis GT0043 gt43 Glucosamine-1-phosphate acetyltransferase COG1207, Cell wall/membrane biogenesis GT0044 gt44 Phosphoribosyl diphosphate synthetase/ribose-phosphate COG0462, Nucleotide transport and metabolism pyrophosphokinase GT0045 gt45 General stress protein COG1825, Translation GT0046 gt46 Peptidyl-tRNA hydrolase COG0193, Translation GT0047 gt47 Conserved hypothetical protein GT0048 gt48 Transcription-repair coupling factor COG1197, Replication, recombination and repair GT0049 gt49 Stage V sporulation protein T COG2002, Transcription GT0050 gt50 Similar to stage V sporulation protein B COG2244, General function prediction only GT0051 gt51 Tetrapyrrole methylase family protein, MazG family protein COG3956, General function prediction only GT0052 gt52 Heat shock protein 15 COG1188, Translation GT0053 gt53 Conserved hypothetical protein GT0054 gt54 Spore cortex biosynthesis protein GT0055 gt55 Cell-division initiation protein COG2919, Cell cycle control, mitosis and meiosis GT0056 gt56 Polyribonucleotide nucleotidyltransferase COG1098, Translation GT0057 gt57 Serine phosphatase COG2208, Signal transduction mechanisms GT0058 gt58 Conserved hypothetical protein GT0059 gt59 Serine/threonine-protein kinase COG0515, General function prediction only GT0060 mesJ Cell cycle protein MesJ COG0037, Cell cycle control, mitosis and meiosis Gene ID Gene Gene product COG functional category name GT0061 gt61 Hypoxanthine-guanine phosphoribosyltransferase COG0634, Nucleotide transport and metabolism GT0062 gt62 Cell-division protein and general stress protein(class III heat-shock) COG0465, Posttranslational modification, protein turnover, chaperones GT0063 coaA Pantothenate kinase COG1521, Transcription GT0064 gt64 Putative 30 kDa replication protein COG1281, Posttranslational modification, protein turnover, chaperones GT0065 gt65 O-acetyl-L-serine sulfhydrylase COG0031, Amino acid transport and metabolism GT0066 gt66 P-aminobenzoate synthase COG0147, Amino acid transport and metabolism GT0067 gt67 Anthranilate synthase component II COG0512, Amino acid transport and metabolism GT0068 gt68 4-amino-4-deoxychorismate lyase COG0115, Amino acid transport and metabolism GT0069 gt69 Dihydropteroate synthase, dihydropteroatepyrophosphorylase COG0294, Coenzyme transport and metabolism GT0070 gt70 Dihydroneopterin aldolase COG1539, Coenzyme transport and metabolism GT0071 gt71 2-amino-4-hydroxy-6- COG0801, Coenzyme transport and metabolism hydroxymethyldihydropteridinepyrophosphokinase GT0072 gt72 Transcriptional regulator Xre family COG1476, Transcription GT0073 gt73 Transcriptional regulator involved in nitrogen regulation, COG0042, Translation NifR3/Smm1 family GT0074 gt74 Lysyl-tRNA synthetase COG1190, Translation GT0075 gt75 Transcriptional regulator COG4463, Transcription GT0076 gt76 ClpC ATPase COG3880, Function unknown GT0077 gt77 Arginine kinase COG3869, Amino acid transport and metabolism GT0078 gt78 Negative regulator of genetic competence ClpC/MecB COG0542, Posttranslational modification, protein turnover, chaperones GT0079 gt79 DNA repair protein homolog COG1066, Posttranslational modification, protein turnover, chaperones Gene ID Gene Gene product COG functional category name GT0080 gt80 Hypothetical membrane associated protein COG4956, General function prediction only GT0081 gt81 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase COG1211, Lipid transport and metabolism GT0082 gt82 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase COG0245, Lipid transport and metabolism GT0083 gt83 Transfer RNA-Gln synthetase COG0008, Translation GT0084 gt84 Serine acetyltransferase COG1045, Amino acid transport and metabolism GT0085 gt85 Cysteine-tRNA ligase COG0215, Translation GT0086 gt86 Conserved hypothetical protein COG1939, Function unknown GT0087 gt87 23S rRNA methyltransferase COG0566, Translation GT0088 gt88 Hypothetical cytosolic protein COG3688, General function prediction only GT0089 gt89 RNA polymerase sigma-30 factor COG1595, Transcription GT0090 rpmG 50S ribosomal protein L33 COG0267,Translation GT0091 gt91 Preprotein translocase SecE subunit COG0690, Intracellular trafficking and secretion GT0092 gt92 Transcription antitermination factor COG0250, Transcription GT0093 gt93 Ribosomal protein L11 COG0080, Translation GT0094 gt94 LSU ribosomal protein L1P COG0081, Translation GT0095 gt95 Ribosomal protein L10 COG0244, Translation GT0096 gt96 LSU ribosomal protein L12P (L7/L12) COG0222, Translation GT0097 gt97 16S rRNA m(2)G 1207 methyltransferase COG2813, Translation GT0098 gt98 DNA-directed RNA polymerase beta subunit COG0085, Transcription GT0099 gt99 RNA polymerase beta subunit COG0086, Transcription GT0100 gt100 LSU ribosomal protein L7AE COG1358, Translation Gene ID Gene Gene product COG functional category name GT0101 gt101 Ribosomal protein S12 COG0048, Translation GT0102 gt102 SSU ribosomal protein S7P COG0049, Translation GT0103 gt103 Translation elongation factor G, EF-G COG0480, Translation GT0104 gt104 EF-Tu COG0050, Translation GT0105 gt105 SSU ribosomal protein S10P COG0051, Translation GT0106 gt106 Ribosomal protein L3 COG0087, Translation GT0107 gt107 Ribosomal protein L4 COG0088, Translation GT0108 gt108 Ribosomal protrein L23 COG0089, Translation GT0109 gt109 Ribosomal protein L2 COG0090, Translation GT0110 gt110 Ribosomal protein S19 COG0185, Translation GT0111 gt111 Ribosomal protein L22 COG0091, Translation GT0112 gt112 Ribosomal protein S3 COG0092, Translation GT0113 gt113 50S ribosomal protein L16 COG0197, Translation GT0114 gt114 Ribosomal protein L29 COG0255, Translation GT0115 gt115 Ribosomal protein L17 COG0186, Translation GT0116 gt116 Ribosomal protein L14 COG0093, Translation GT0117 gt117 Ribosomal protein L5 COG0094, Translation GT0118 gt118 SSU ribosomal protein S14P COG0199, Translation GT0119 gt119 SSU ribosomal protein S8P COG0096, Translation GT0120 gt120 Ribosomal protein L6 COG0097, Translation GT0121 gt121 Ribosomal protein L18 COG0256, Translation Gene ID Gene Gene product COG functional category name GT0122 gt122 Ribosomal protein S5 COG0098, Translation GT0123 gt123 50S ribosomal protein L30 COG1841, Translation GT0124 gt124 Ribosomal protein L15 COG0200, Translation GT0125 secY SecY COG0201, Intracellular trafficking and secretion GT0126 adk Adenylate kinase COG0563, Nucleotide transport and metabolism GT0127 gt127 Methionine aminopeptidase COG0024,