June 11, 2019 u vol. 116 u no. 24 From the Cover 11845 Germline-restricted chromosome in songbirds 11679 Historical impact of Sumatran tsunami 11712 Earliest known Oldowan stone tools 11786 Placental stem cells and heart regeneration 11857 Genomic basis of bumble bee mimicry Contents THIS WEEK IN PNAS Cover image: Pictured is a male 11555 In This Issue Eurasian bullfinch (Pyrrhula pyrrhula). Anna A. Torgasheva et al. found that germ cells of bullfinches and other OPINION—Leading scientists discuss current issues songbirds contain an additional 11558 The proposed change to the definition of “waters of the United States” flouts chromosome that is absent from somatic sound science cells. The germline-restricted S. Mazeika P. Sullivan, Mark C. Rains, and Amanda D. Rodewald chromosomes are composed of highly duplicated genetic material partially homologous to the somatic QNAS chromosomes and may have evolved from a microchromosome in the 11562 QnAs with Alexander Levitzki common ancestor of songbirds. See the Sandeep Ravindran article by Torgasheva et al. on pages See Inaugural Article on page 11579 11845–11850. Image courtesy of Elena P. Shnaider. PROFILE 11564 Profile of Junying Yuan Jennifer Viegas See Inaugural Article on page 9714 in issue 20 of volume 116 COMMENTARIES 11567 Searching for the emergence of stone tool making in eastern Africa Ignacio de la Torre See companion article on page 11712 11570 On the origin and evolution of germline chromosomes in songbirds Bengt Hansson See companion article on page 11845 11573 Shift in temporal and spatial expression of Hox gene explains color mimicry in bees Sydney A. Cameron and James B. Whitfield See companion article on page 11857 LETTERS 11575 Do cluster roots of red alder play a role in nutrient acquisition from bedrock? Hans Lambers, Diego L. Nascimento, Rafael S. Oliveira, and Jianmin Shi Free online through the PNAS open access option. PNAS u June 11, 2019 u vol. 116 u no. 24 u iii–vii Downloaded by guest on September 23, 2021 11577 Reply to Lambers et al.: How does nitrogen-fixing red 11630 Stabilization of reactive Co4O4 cubane oxygen- alder eat rocks? evolution catalysts within porous frameworks Steven S. Perakis and Julie C. Pett-Ridge Andy I. Nguyen, Kurt M. Van Allsburg, Maxwell W. Terban, Michal Bajdich, Julia Oktawiec, Jaruwan Amtawong, Micah S. Ziegler, James P. Dombrowski, K. V. Lakshmi, Walter S. INAUGURAL ARTICLE Drisdell, Junko Yano, Simon J. L. Billinge, and T. Don Tilley 11579 My journey from tyrosine phosphorylation inhibitors to targeted immune therapy as strategies to EARTH, ATMOSPHERIC, AND PLANETARY SCIENCES combat cancer 11640 Mechanistic evidence for tracking the seasonality of Alexander Levitzki and Shoshana Klein photosynthesis with solar-induced fluorescence See QnAs on page 11562 Troy S. Magney, David R. Bowling, Barry A. Logan, Katja Grossmann, Jochen Stutz, Peter D. Blanken, Sean P. Burns, Rui Cheng, Maria A. Garcia, Philipp Kӧhler, Sophia BRIEF REPORT Lopez, Nicholas C. Parazoo, Brett Raczka, David Schimel, 11587 Photocontrollable mononegaviruses and Christian Frankenberg Maino Tahara, Yuto Takishima, Shohei Miyamoto, Yuichiro 11646 Decadal trends in the ocean carbon sink Nakatsu, Kenji Someya, Moritoshi Sato, Kenzaburo Tani, Tim DeVries, Corinne Le Que´re´, Oliver Andrews, Sarah and Makoto Takeda Berthet, Judith Hauck, Tatiana Ilyina, Peter Landschu¨tzer, Andrew Lenton, Ivan D. Lima, Michael Nowicki, Jo¨rg PHYSICAL SCIENCES Schwinger, and Roland Se´fe´rian 11652 Low-gradient, single-threaded rivers prior to APPLIED PHYSICAL SCIENCES greening of the continents 11590 Adverse organogenesis and predisposed long-term Vamsi Ganti, Alexander C. Whittaker, Michael P. Lamb, metabolic syndrome from prenatal exposure to and Woodward W. Fischer fine particulate matter 11658 Multiphase reactivity of polycyclic aromatic Guoyao Wu, Jacob Brown, Misti L. Zamora, Alyssa Miller, M. hydrocarbons is driven by phase separation Carey Satterfield, Cynthia J. Meininger, Chelsie B. Steinhauser, and diffusion limitations Gregory A. Johnson, Robert C. Burghardt, Fuller W. Bazer, Shouming Zhou, Brian C. H. Hwang, Pascale S. J. Lakey, Andreas Yixin Li, Natalie M. Johnson, Mario J. Molina, and Renyi Zhang Zuend, Jonathan P. D. Abbatt, and Manabu Shiraiwa 11596 Self-sustaining thermophotonic circuits Bo Zhao, Siddharth Buddhiraju, Parthiban Santhanam, Kaifeng ENGINEERING Chen, and Shanhui Fan 11664 Implantable multireservoir device with stimulus- 11718 Multifunctional graphene supports for responsive membrane for on-demand and electron cryomicroscopy pulsatile delivery of growth hormone Katerina Naydenova, Mathew J. Peet, and Christopher J. Russo Seung Ho Lee, Huiyan Piao, Yong Chan Cho, Se-Na Kim, Goeun Choi, Cho Rim Kim, Han Bi Ji, Chun Gwon Park, Cheol BIOPHYSICS AND COMPUTATIONAL BIOLOGY Lee, Chong In Shin, Won-Gun Koh, Young Bin Choy, and Jin-Ho Choy 11602 Laser- and cryogenic probe-assisted NMR enables hypersensitive analysis of biomolecules at submicromolar concentration PHYSICS Yusuke Okuno, Miranda F. Mecha, Hanming Yang, Lingchao 11673 Quantum phase-sensitive diffraction and imaging Zhu, Charles G. Fry, and Silvia Cavagnero using entangled photons 11764 Torque-dependent remodeling of the bacterial Shahaf Asban, Konstantin E. Dorfman, and Shaul Mukamel flagellar motor Navish Wadhwa, Rob Phillips, and Howard C. Berg SOCIAL SCIENCES 11956 Conformational plasticity of the intracellular cavity of GPCR−G-protein complexes leads to G-protein ENVIRONMENTAL SCIENCES promiscuity and selectivity 11679 Archaeological evidence that a late 14th-century Manbir Sandhu, Anja M. Touma, Matthew Dysthe, Fredrik tsunami devastated the coast of northern Sadler, Sivaraj Sivaramakrishnan, and Nagarajan Vaidehi Sumatra and redirected history Patrick Daly, Kerry Sieh, Tai Yew Seng, Edmund CHEMISTRY Edwards McKinnon, Andrew C. Parnell, Ardiansyah, R. Michael Feener, Nazli Ismail, Nizamuddin, 11612 A neural network protocol for electronic excitations and Jedrzej Majewski of N-methylacetamide Sheng Ye, Wei Hu, Xin Li, Jinxiao Zhang, Kai Zhong, Guozhen Zhang, Yi Luo, Shaul Mukamel, and Jun Jiang PSYCHOLOGICAL AND COGNITIVE SCIENCES 11618 Direct high-resolution mapping of electrocatalytic 11687 Individual differences in visual salience vary along activity of semi-two-dimensional catalysts with semantic dimensions single-edge sensitivity Benjamin de Haas, Alexios L. Iakovidis, D. Samuel Schwarzkopf, and Karl R. Gegenfurtner Tong Sun, Dengchao Wang, Michael V. Mirkin, Hao Cheng, Jin-Cheng Zheng, Ryan M. Richards, Feng Lin (林锋), 11693 Historical roots of implicit bias in slavery and Huolin L. Xin B. Keith Payne, Heidi A. Vuletich, and Jazmin L. Brown-Iannuzzi 11624 Using attribution to decode binding mechanism in 11699 A scarcity mindset alters neural processing neural network models for chemistry underlying consumer decision making Kevin McCloskey, Ankur Taly, Federico Monti, Michael P. Inge Huijsmans, Ili Ma, Leticia Micheli, Claudia Civai, Mirre Brenner, and Lucy J. Colwell Stallen, and Alan G. Sanfey iv u www.pnas.org Contents Downloaded by guest on September 23, 2021 11705 The emergence of the formal category “symmetry” in 11770 Adjustment in tumbling rates improves bacterial a new sign language chemotaxis on obstacle-laden terrains Lila Gleitman, Ann Senghas, Molly Flaherty, Marie Coppola, Sabrina Rashid, Zhicheng Long, Shashank Singh, Maryam and Susan Goldin-Meadow Kohram, Harsh Vashistha, Saket Navlakha, Hanna Salman, Zolta´n N. Oltvai, and Ziv Bar-Joseph BIOLOGICAL SCIENCES CELL BIOLOGY AGRICULTURAL SCIENCES 11776 Coupling of COPII vesicle trafficking to nutrient 11590 Adverse organogenesis and predisposed long-term availability by the IRE1α-XBP1s axis metabolic syndrome from prenatal exposure to Lin Liu, Jie Cai, Huimin Wang, Xijun Liang, Qian Zhou, Chenyun fine particulate matter Ding, Yuangang Zhu, Tingting Fu, Qiqi Guo, Zhisheng Xu, Liwei Xiao, Jing Liu, Yujing Yin, Lei Fang, Bin Xue, Yan Wang, Guoyao Wu, Jacob Brown, Misti L. Zamora, Alyssa Miller, M. Zhuo-Xian Meng, Aibin He, Jian-Liang Li, Yong Liu, Xiao-Wei Carey Satterfield, Cynthia J. Meininger, Chelsie B. Steinhauser, Chen (陈晓伟), and Zhenji Gan Gregory A. Johnson, Robert C. Burghardt, Fuller W. Bazer, Yixin Li, Natalie M. Johnson, Mario J. Molina, and Renyi Zhang 11786 Multipotent fetal-derived Cdx2 cells from placenta regenerate the heart ANTHROPOLOGY Sangeetha Vadakke-Madathil, Gina LaRocca, Koen 11712 Earliest known Oldowan artifacts at >2.58 Ma Raedschelders, Jesse Yoon, Sarah J. Parker, Joseph from Ledi-Geraru, Ethiopia, highlight early Tripodi, Vesna Najfeld, Jennifer E. Van Eyk, technological diversity and Hina W. Chaudhry David R. Braun, Vera Aldeias, Will Archer, J Ramon Arrowsmith, 11796 Quantitative proteomics of MDCK cells identify Niguss Baraki, Christopher J. Campisano, Alan L. Deino, unrecognized roles of clathrin adaptor AP-1 in Erin N. DiMaggio, Guillaume Dupont-Nivet, Blade Engda, polarized distribution of surface proteins David A. Feary, Dominique I. Garello, Zenash Kerfelew, Paulo S. Caceres, Diego Gravotta, Patrick J. Zager, Noah Shannon P. McPherron, David B. Patterson, Jonathan S. Dephoure, and Enrique Rodriguez-Boulan Reeves, Jessica C. Thompson, and Kaye E. Reed See Commentary on page 11567 DEVELOPMENTAL BIOLOGY APPLIED BIOLOGICAL SCIENCES 11806 Fate plasticity and reprogramming in genetically 11579 My journey from tyrosine phosphorylation inhibitors distinct populations of Danio leucophores to targeted immune therapy as strategies to Victor M. Lewis, Lauren M. Saunders, Tracy A. Larson, Emily J.