Rabbit Anti-Human H2BFS (Acetyl-Lys15) polyclonal antibody (CABT-L3628) This product is for research use only and is not intended for diagnostic use. PRODUCT INFORMATION Product Overview Rabbit Anti-Human ATRIP (Phospho-Ser224) polyclonal antibody. This antibody detects endogenous levels of total Histone H2B protein only when acetylated at Lys15. Specificity Target Modification: Acetyl. Modification Sites: Human: K15; Mouse: K15 Target Human Histone H2B (Acetyl-Lys15) Immunogen The antiserum was produced against synthesized peptide derived from human Histone H2B around the acetylated site of Lys15. Immunogen range: 11-60 Isotype IgG Source/Host Rabbit Species Reactivity Human, Mouse Purification Affinity Purified Conjugate Unconjugated Applications WB, IHC, IF, ELISA Molecular Weight 13 kDa Preparation The antibody was purified from rabbit antiserum by affinity-chromatography using acetylated peptide. The antibody against non-acetylated peptide was removed by chromatography using corresponding non-acetylated peptide. Format Liquid Concentration Lot specific Buffer Rabbit IgG in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl and 50% glycerol. Preservative 0.02% Sodium Azide Storage Stable at -20°C for at least 1 year. Ship Wet ice Warnings For research use only. 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved BACKGROUND Introduction H2BFS (H2B histone family, member S (pseudogene)) is a pseudogene, and is affiliated with the lncRNA class. Diseases associated with H2BFS include endometrial stromal sarcoma, and male infertility, and among its related super-pathways are Signal transduction Activin A signaling regulation and Telomere Maintenance. GO annotations related to this gene include DNA binding and protein heterodimerization activity. Histone H2B type F-S is a protein that in humans is encoded by the H2BFS gene. 0The function about H2BFS antigen include DNA binding; protein heterodimerization activity. Keywords H2BFS;H2B histone family, member S (pseudogene); GENE INFORMATION Gene Name H2BFS H2B histone family, member S (pseudogene) [ Homo sapiens (human) ] Official Symbol H2BFS Synonyms Histone cluster 1, H2bb, H2B.1, H2B/f, H2BFF, H2B histone family, member F, histone 1, H2bb Entrez Gene ID 54145 UniProt ID P57053 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved.