OriGene Technologies, Inc. OriGene Technologies GmbH 9620 Medical Center Drive, Ste 200 Schillerstr. 5 Rockville, MD 20850 32052 Herford UNITED STATES GERMANY Phone: +1-888-267-4436 Phone: +49-5221-34606-0 Fax: +1-301-340-8606 Fax: +49-5221-34606-11 [email protected] [email protected] AR51864PU-S Human IL1F10 / FIL1T (1-152, ) - Purified Alternate names: FKSG75, IL-1F10, IL1HY2, Interleukin-1 HY2, Interleukin-1 family member 10, Interleukin-1 receptor antagonist-like FIL1 theta Quantity: 0.1 mg Concentration: 1.0 mg/ml (determined by Bradford assay) Background: IL1F10 also known as interleukin-1 family member 10. IL1F10 is cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. It reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. It increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS) and ligand for IL-36R/IL1RL2. Recombinant human IL1F10 was expressed in E.coli and purified by using conventional chromatography techniques Uniprot ID: Q8WWZ1 NCBI: NP_115945 GeneID: 84639 Species: Human Source: E. coli Format: State: Liquid purified protein Purity: >95% by SDS - PAGE Buffer System: Phosphate buffered saline (pH7.4). Description: AA Sequence: MCSLPMARYY IIKYADQKAL YTRDGQLLVG DPVADNCCAE KICTLPNRGL DRTKVPIFLG IQGGSRCLAC VETEEGPSLQ LEDVNIEELY KGGEEATRFT FFQSSSGSAF RLEAAAWPGW FLCGPAEPQQ PVQLTKESEP SARTKFYFEQ SW Molecular weight: 16.9 kDa (152aa) confirmed by MALDI-TOF Storage: Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. General Readings: Bensen J.T., et al. (2001) J. Interferon Cytokine Res. 21:899-904. van de Veerdonk F.L., et al. (2012) Proc. Natl. Acad. Sci. u.S.A. 109:3001-3005. For research and in vitro use only. Not for diagnostic or therapeutic work. Material Safety Datasheets are available at www.acris-antibodies.com or on request. MP/20140724 1 / 2 AR51864PU-S: Human IL1F10 / FIL1T (1-152, ) - Purified Pictures: For research and in vitro use only. Not for diagnostic or therapeutic work. Material Safety Datasheets are available at www.acris-antibodies.com or on request. MP/20140724 2 / 2 Powered by TCPDF (www.tcpdf.org).