Prescription Medications, Over- the-Counter Drugs, Herbs & Chemicals Associated with Tinnitus 2013 Edition Compiled by Neil G. Bauman, Ph.D. The Center for Hearing Loss Help 49 Piston Court, Stewartstown, PA 17363 717-993-8555; http://www.hearinglosshelp.com Prescription Medications, Over-the-Counter Drugs, Herbs & Chemicals Associated with Tinnitus Prescription Medications, Over-the-Counter Drugs, Herbs & Chemicals Associated with Tinnitus The following list contains all the drugs, herbals and chemicals that have been associated with tinnitus and were known to the author at the time of compiling this document. Although this list is one of the most complete listings of drugs associated with tinnitus, no list of this kind can ever be totally complete. New drugs are coming to the market all the time. Furthermore, some existing drugs not listed here will be found to cause tinnitus in the future. Therefore, use this list as a guide and discussion tool with your doctor, and as a springboard to further research on any drugs you may be taking or are considering taking. More than 550 drugs, herbals and chemicals are currently associated with tinnitus. However, just because a drug is listed here does not mean that you will automatically get tinnitus or exacerbate your existing tinnitus if you take it. Some drugs result in tinnitus occurring in a high percentage of those taking it. With other drugs, tinnitus only seems to occur rarely. Sometimes the resulting tinnitus is permanent. Other times the tinnitus goes away in a few days to a few weeks. Sometimes the tinnitus is mild. Other times it can be so loud that it is debilitating. 2 Copyright 2013 by the Center for Hearing Loss Help, Stewartstown, PA. All rights reserved. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form, or by any means, without the prior written permission of the Center for Hearing loss Help. http://www.hearinglosshelp.com. Prescription Medications, Over-the-Counter Drugs, Herbs & Chemicals Associated with Tinnitus Whether or not you experience tinnitus after taking one of the listed drugs or herbals, or after being exposed to one of the listed chemicals, depends on many factors such as your own body chemistry, your sensitivity to drugs, the dose you take, the length of time you take the drug, etc. Therefore, use this document as a preliminary tool in your quest to discover whether one of the drugs listed here is causing your tinnitus or making your existing tinnitus worse. For more detailed information on the probability (risk) of getting tinnitus from taking any drug, as well as a guide to the likely severity and permanence of any resulting tinnitus for any drug, herbal or chemical listed here, see the author’s book, Ototoxic Drugs Exposed, 3rd edition. In addition, this book lists information about the other ototoxic (ear-damaging) side effects of these drugs such as hearing loss, hyperacusis, ear infections, ear pain and a number of balance problems. If you wish to learn more about tinnitus and how you can help yourself bring it under control, see the author’s book, When Your Ears Ring!—Cope With Your Tinnitus—Here’s How now in it’s fifth edition. You can obtain a copy of either of these books on the Center’s website at: http://www.hearinglosshelp.com/products/books.htm. You should not discontinue taking any prescribed medication without first contacting your prescribing physician. Drug brand names are italicized. Generic drug names are in bold. Please note that not every brand name is included as some drugs have numerous brand names. Neil Bauman, Ph.D. Stewartstown, PA 3 Copyright 2013 by the Center for Hearing Loss Help, Stewartstown, PA. All rights reserved. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form, or by any means, without the prior written permission of the Center for Hearing loss Help. http://www.hearinglosshelp.com. Prescription Medications, Over-the-Counter Drugs, Herbs & Chemicals Associated with Tinnitus Medications & Drugs Adapin (Doxepin) Adcirca (Tadalafil) Adipex-P (Phentermine) Drug Brand Name (Generic Drug Name) or Generic Drug Name (only) Adriamycin (Doxorubicin) Advagraf (Tacrolimus) 222 (Acetylsalicylic acid) Advil (Ibuprofen) 282 (Acetylsalicylic acid) Advil Cold & Sinus (Ibuprofen) 282 MEP (Acetylsalicylic acid) Afloxan (Proglumetacin) 292 (Acetylsalicylic acid) Agalsidase alfa 5-ASA (Mesalamine) Agalsidase beta 692 (Acetylsalicylic acid) Aggrenox (Acetylsalicylic acid) Agrylin (Anagrelide) A Airomir (Albuterol) Abatacept Alatrofloxacin (Trovafloxacin) Abelcet (Amphotericin B) Albert Tiafen (Tiaprofenic acid) Abilify (Aripiprazole) Albuterol Acamprosate Alclofenac AccuNeb (Albuterol) Aldoril (Hydrochlorothiazide) Accupril (Quinapril) Aleve (Naproxen) Accuretic (Quinapril) Alferon N (Interferon alfa-n3) Accutane (Isotretinoin) Alka-Seltzer (Acetylsalicylic acid) Acebutolol Allegra (Fexofenadine) Aceclofenac Allegra-D (Fexofenadine) Acemetacin Aller-Chlor (Chlorpheniramine) Aceon (Perindopril) Allopurinol Acetazolamide Almogran (Almotriptan) Acetylsalicylic acid Almotriptan Achromycin (Tetracycline) Aloxi (Palonosetron) Aciphex (Rabeprazole) Alprazolam Acitretin Altace (Ramipril) Acthar (Corticotropin) Alumadrine (Phenylpropanolamine) Actifed (Pseudoephedrine) Ambien (Zolpidem) Actiq (Fentanyl) Ambien CR (Zolpidem) Actonel (Risedronate) AmBisome (Amphotericin B) Adalat (Nifedipine) Amen (Medroxyprogesterone) Adalimumab Amerge (Naratriptan) 4 Copyright 2013 by the Center for Hearing Loss Help, Stewartstown, PA. All rights reserved. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form, or by any means, without the prior written permission of the Center for Hearing loss Help. http://www.hearinglosshelp.com. Prescription Medications, Over-the-Counter Drugs, Herbs & Chemicals Associated with Tinnitus Amezinium Apo-Carvedilol (Carvedilol) Amicar (Aminocaproic acid) Apo-Cetirizine (Cetirizine) Amikacin Apo-Clorazepate (Clorazepate) Amikin (Amikacin) Apo-Diltiaz (Diltiazem) Amiloride Apo-Divalproex (Divalproex) Aminocaproic acid Apo-Doxepin (Doxepin) Aminopyrine Apo-Etodolac (Etodolac) Aminosidine—Paromomycin Apo-Fenofibrate (Fenofibrate) Amiodarone Apo-Feno-Micro (Fenofibrate) Amitriptyline Apo-Floctafenine (Floctafenine) Amlodipine Apo-Fluvoxamine (Fluvoxamine) Amoebriz (Mebendazole) Apo-Gabapentin (Gabapentin) Amonafide Apo-Hydro (Hydrochlorothiazide) Amoxapine Apo-Indapamide (Indapamide) Amphotec (Amphotericin B) Apo-Keto (Ketoprofen) Amphotericin B Apo-Ketorolac (Ketorolac) Ampyrone (Aminopyrine) Apo-Lisinopril (Lisinopril) Amrix (Cyclobenzaprine) Apo-Loratadine (Loratadine) Amtolmetin Apo-Mefenamic (Mefenamic acid) Amturnide (Amlodipine) Apo-Methazolamide (Methazolamide) Anacin (Acetylsalicylic acid) Apo-Midazolam (Midazolam) Anafranil (Clomipramine) Apo-Misoprostol (Misoprostol) Anagrelide Apo-Moclobemide (Moclobemide) Anaprox (Naproxen) Apo-Nabumetone (Nabumetone) Andante (Bunazosin) Apo-Norflox (Norfloxacin) Anexate (Flumazenil) Apo-Nortriptyline (Nortriptyline) Angeliq (Estradiol) Apo-Oxaprozin (Oxaprozin) Ansaid (Flurbiprofen) Apo-Phenylbutazone (Phenylbutazone) Antivert (Meclizine) Apo-Prazo (Prazosin) Antizol (Fomepizole) Apo-Selegiline (Selegiline) Anzemet (Dolasetron) Apo-Temazepam (Temazepam) Aplenzin (Bupropion) Apo-Tenoxicam (Tenoxicam) Apo-Acebutolol (Acebutolol) Apo-Timol (Timolol) Apo-Amiloride (Amiloride) Apo-Trimethoprim (Trimethoprim) Apo-Beclomethasone (Beclomethasone) Apo-Valproic (Valproic acid) Apo-Butorphanol (Butorphanol) Aprepitant 5 Copyright 2013 by the Center for Hearing Loss Help, Stewartstown, PA. All rights reserved. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form, or by any means, without the prior written permission of the Center for Hearing loss Help. http://www.hearinglosshelp.com. Prescription Medications, Over-the-Counter Drugs, Herbs & Chemicals Associated with Tinnitus Apresazide (Hydrochlorothiazide) Avapro (Irbesartan) Apri 28 (Ethinyl estradiol) Avelox (Moxifloxacin) Apriso (Mesalamine) Aventyl (Nortriptyline) Aralen (Chloroquine) Avlosulfon (Dapsone) Arcoxia (Etoricoxib) Avonex (Interferon beta-1a) Arestin (Minocycline) Axert (Almotriptan) Aricept (Donepezil) Axocet (Butalbital) Aripiprazole Azactam (Aztreonam) Arsenic trioxide Azapropazone Artemether/Lumefantrine Azatadine Arthrotec (Diclofenac) Azithromycin Articaine AZT (Zidovudine) Artromed (Amtolmetin) Aztreonam ASA (Acetylsalicylic acid) Azulfidine (Sulfasalazine) Asacol (Mesalamine) Asasantine (Acetylsalicylic acid) B Ascriptin (Acetylsalicylic acid) Backache Caplets (Magnesium salicylate) Asendin (Amoxapine) Baclofen Asmavent (Albuterol) Bactrim (Trimethoprim) Aspirin (Acetylsalicylic acid) Bayer Aspirin (Acetylsalicylic acid) Aspirin Backache (Acetylsalicylic acid) BC Powder (Acetylsalicylic acid) Astromicin Beclomethasone Atacand (Candesartan) Beconase (Beclomethasone) Atacand HCT (Candesartan) Benadryl (Diphenhydramine) Atacand Plus (Candesartan) Benazepril Atenolol Bendectin (Doxylamine) Ativan (Lorazepam) Bendroflumethiazide Atorvastatin BenGay (Methyl salicylate) Atovaquone/Proguanil Benoral (Benorilate) Atretol (Carbamazepine) Benorilate Atripla (Efavirenz) Benorylate (Benorilate) Atrohist (Pyrilamine) Benoxaprofen Atrohist Plus (Phenylpropanolamine) Bepridil Atrovent (Ipratropium) Betaloc (Metoprolol) Auranofin Betaseron (Interferon beta-1b) Avalide (Irbesartan) Betaxolol 6 Copyright 2013 by the Center for Hearing