Purdue University Purdue e-Pubs Open Access Dissertations Theses and Dissertations Fall 2013 Structural Analysis of Carbohydrates by Mass Spectrometry Chiharu Konda Purdue University Follow this and additional works at: https://docs.lib.purdue.edu/open_access_dissertations Part of the Analytical Chemistry Commons Recommended Citation Konda, Chiharu, "Structural Analysis of Carbohydrates by Mass Spectrometry" (2013). Open Access Dissertations. 141. https://docs.lib.purdue.edu/open_access_dissertations/141 This document has been made available through Purdue e-Pubs, a service of the Purdue University Libraries. Please contact [email protected] for additional information. Graduate School ETD Form 9 (Revised 12/07) PURDUE UNIVERSITY GRADUATE SCHOOL Thesis/Dissertation Acceptance This is to certify that the thesis/dissertation prepared By Chiharu Konda Entitled Structural Analysis of Carbohydrates by Mass Spectrometry Doctor of Philosophy For the degree of Is approved by the final examining committee: Yu Xia Chair Peter T. Kissinger Nikolai R. Skrynnikov Hilkka I. Kenttamaa To the best of my knowledge and as understood by the student in the Research Integrity and Copyright Disclaimer (Graduate School Form 20), this thesis/dissertation adheres to the provisions of Purdue University’s “Policy on Integrity in Research” and the use of copyrighted material. Approved by Major Professor(s): ____________________________________Yu Xia ____________________________________ Approved by: Robert E. Wild 10/25/2013 Head of the Graduate Program Date i STRUCTURAL ANALYSIS OF CARBOHYDRATES BY MASS SPECTROMETRY A Dissertation Submitted to the Faculty of Purdue University by Chiharu Konda In Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy December 2013 Purdue University West Lafayette, Indiana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