MEDICC Review April–July 2019 Vol 21, No 2–3 Editors’ Choice Personalized HIV Care 59 HT in Cuban Children 10 Salvadoran CKD Epidemic 29 Forecasting Dengue, Colombia 38 Geriatric Assistive Devices, Chile 46 Peer reviewed since 2007 www.mediccreview.org "DPOUJOVJOHNFEJDBMFEVDBUJPOTVNNJU "DPOUJOVJOHNFEJDBMFEVDBUJPOTVNNJU by Rush University Medical Center Medical University Rush by by Rush University Medical Center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hicago, IL IL Chicago, Drake The )PUFM The Drake Chicago, IL 20 & 21 2019 21 & 20 b SEPTEMBER SEPTEMBERb20 & 21 2019 SUMMIT SUMMIT MEDICINE MEDICINE WOMEN IN WOMEN WOMEN IN OE MEDICINE WOMEN WOMEN MEDICINE Editor-in-Chief C. William Keck MD MPH FACPM Executive Editor Gail Reed MS Senior Editors Conner Gorry MA April–July 2019, Vol 21, No 2–3 Elizabeth Vasile PhD Primary Issue Coordinator EDITORIAL Jorge Bacallao PhD DrSc 3 The Long March for Science in Defense of Population Health Issue Coordinators ABOUT THE CONTRIBUTORS Alina Alerm MD MS 4 Lila Castellanos PhD DrSc Gisele Coutin MD MS ERRATUM Esther María Fajardo MS 4 Editorial Associates LETTERS Anna Kovac 5 Annet Sánchez INTERVIEW Copy Editor 6 Gender & Race in Cuba: An Anthropological Perspective Carolyn Gorry Lourdes Serrano Peralta PhD, Cuban Anthropology Institute Communications Consultant Conner Gorry MA Elizabeth Sayre MA ORIGINAL RESEARCH Publishing & Marketing 10 Biochemical Markers and Hypertension in Children Aram Álvarez MFA Merlin Garí-Llanes MD MS, et al. Silvia García Yenny Leal 16 Normal Values of T, B and NK Lymphocyte Subpopulations Murlean Tucker in Peripheral Blood of Healthy Cuban Adults Elena Kokuina MD PhD, et al. Translators Pamela Boyle 22 Corrected QT-Interval Dispersion: Roxane K. Dow MA An Electrocardiographic Tool to Predict Recurrence of Myocardial Infarction Susan Greenblatt MPH Ailed Elena Rodríguez-Jiménez MD MS, et al. Eloisa Le Riverend MS Lyle Prescott 29 The Chronic Kidney Disease Epidemic in El Salvador: A Cross-Sectional Study Maxine Siri MS Carlos Manuel Orantes-Navarro MD, et al. MEDICC Review is indexed in: 38 Dengue Cases in Colombia: Mathematical Forecasts for 2018–2022 MEDLINE®/PubMed® Luis Eduardo López-Montenegro MS PhD, et al. 46 Assistive Devices for Older Adults: A Longitudinal Study of Policy Effectiveness, Santiago, Chile, 2014–2016 Macarena Hirmas-Adauy MPH, et al. LESSONS FROM THE FIELD 54 The Panama Aging Research Initiative Longitudinal Study Global Health Alcibiades E. Villarreal PhD, et al. Tropical Diseases Bulletin ELSEVIER EMBASE REVIEW ARTICLE SCOPUSTM 59 Pharmacogenetic Markers: A Path toward Individualized HIV Therapy Danays García-Blanco, et al. 69 Cuban Public Health History: The 19th Century Board of Health in the City of Holguín Adiuska Calzadilla-González MS, et al. MEDICC Review's mission is to uphold the highest VIEWPOINT standards of ethics and excellence, publishing open- 75 Increasing Research Productivity across Africa access articles in English relevant to global health Bankole K. Oyewole MBChB, et al. equity that offer the best of medical, public health and social sciences research and perspectives by Cuban and other developing-country professionals. 76 Physiology without Borders: US and Cuban Scientists Meet in Space Alberto Juan Dorta-Contreras MS PhD MEDICC Review is published by MEDICC, a US nonprofi t organization founded in 1997 to enhance ABSTRACTS cooperation among the US, Cuban and global health communities aimed at improved health and equity. Cuban Research in Current International Journals MEDICC Review online (ISSN 1527-3172) is an Cover and back cover photos: E. Añé. Murals by GTG, the Gorría Gallery and Workshop open-access publication: see our Creative Commons in Old Havana's San Isidro neighborhood. Founded by actor Jorge Perugorría as a public License online for details. space for artistic creation, experimentation and performances. For more: [email protected] www.mediccreview.org Copyright © 2019, MEDICC Available online only MEDICC Review Editorial Board Neil Arya BASc MD CCFP FCFP Lowell Gerson PhD Daniel J. Ncayiyana MD FACOG Director, Offi ce of Global Health Professor Emeritus of Family & Community Medicine Emeritus Professor, University of Cape Town Schulich School of Medicine and Dentistry Northeast Ohio Medical University, USA South Africa Western University, Canada Tee L. Guidotti MD, MPH, DABT André-Jacques Neusy MD DTM&H Rifat Atun MBBS MBA FRCGP FFPH FRCP Consultant, Occupational + Environmental Health Senior Director, Training for Health Equity Network Professor of Global Health Systems and Medicine, Toronto, Canada THEnet, USA Director, Health Systems Cluster, Harvard University School of Public Health, USA Jean Handy PhD F. Javier Nieto MD PhD Associate Professor of Microbiology & Immunology Dean, College of Public Health & Human Sciences, Michael Bird MSW MPH University of North Carolina School of Medicine, USA Oregon State University, USA Public Health Consultant, Kewa Pueblo Health Board Urban Indian Health Commission Barbara J. Hatcher PhD MPH RN FAAN Peter Orris MD MPH Albuquerque, New Mexico, USA Associate Professor, George Mason University Professor and Chief, Occupational and College of Nursing & Health Sciences, USA Environmental Medicine, University of Illinois James Boex PhD MBA Hospital and Health Sciences System, USA Emeritus Professor of Medical Education Raúl Herrera MD PhD DrSc Univ. of Cincinnati College of Medicine, USA Distinguished Professor, Medical University of Havana Jorge Pérez MD MS Chair, National Nephrology Group, Cuba Adviser to the Director, and Full Professor Peter Bourne MD MA Pedro Kourí Tropical Medicine Institute, Cuba Visiting Senior Research Fellow Eve J. Higginbotham SM MD Green Templeton College, University of Oxford, UK Vice Dean for Diversity & Inclusion, University of Patricia Rodney PhD MPH RN Pennsylvania, Perelmen School of Medicine, USA Partners in Health, Education and Development, Alfred Brann MD USA Professor of Pediatrics Sharon K. Hull MD MPH Emory University School of Medicine, USA Founder and CEO, Metta Solutions, USA María Isabel Rodríguez MD Health and Education Advisor to the President of the Jaime Breilh MD PhD MSc C. William Keck MD MPH FACPM Republic, El Salvador Director, Health Department Professor Emeritus, Family and Community Universidad Andina Simón Bolívar, Ecuador Medicine Northeast Ohio Medical University Francisco Rojas Ochoa MD PhD Chair, Council on Linkages, USA Distinguished Professor, Medical University of Havana, Paulo M. Buss MD MPH Cuba Director, FIOCRUZ Center for Global Health Ann Marie Kimball MD MPH FACPM Oswaldo Cruz Foundation, Brazil Senior Consulting Fellow, Chatham House Royal F. Douglas Scutchfi eld MD FACPM FAAP Institute of Foreign Affairs, USA Peter P. Bosomworth Professor of Health Services Pastor Castell-Florit MD PhD DrSc Research and Policy, University of Kentucky Director, National School of Public Health, Cuba Barry Kistnasamy MBChB Mmed Colleges of Public Health and Medicine, USA Executive Director, National Institute for Occupa- José F. Cordero MD MPH tional Health & the National Cancer Registry Stuart G. Shanker DPhil MA Patel Distinguished Professor of Public Health South Africa Distinguished Research Professor of Philosophy and Chair, Department of Epidemiology and Biostatistics Psychology; Director, Milton & Ethel Harris Research College of Public Health, University of Georgia Patrick Kuma-Aboagye MB-BCH MPH Initiative, York University, Canada USA Deputy Director and Head, Reproductive and Child Health Department, Ghana Health Service, Ghana Augusto Sola MD Yamila de Armas MD Neonatologist, St Jude’s Hospital and Children’s Professor, National School of Public Health, Cuba Albert Kuperman PhD Hospital, Orange County, California, USA Emeritus Associate Dean for Medical Education Maria Cecilia de Souza