With a family of Xmatrx® systems, you have the freedom to Molecular Pathology Catalog Molecular Pathology Catalog attend to more demanding tasks while delivering high-quality and standardized results every time 2014 - 2015 (International) Microtome to Microscope IHC | Special Stains | FISH* & ISH | miRNA | Multiplex IHC & ISH | in situ PCR 2014 - 2015 All-in-One All-at-Once • TheT World’s First and Only Fully Automated Front-end FISH Processing System • RRun up to 40 slides under multiple protocols • RReduce hands-on tech time from 7.5 hours to 30 minutes ThreeT Simple Steps Load Click View Doc. No. 937-4083.0 *Optional Software for Research Use Only In the U.S., call +1 (800) 421-4149 © 2014 BioGenex Laboratories, Inc. All Rights Reserved ISO 13485:2003 Outside the U.S., call +91-40-27185500 www.biogenex.com FM 78972 For distribution worldwide except USA and Canada Dear Customer, We are pleased to present the BioGenex Molecular Pathology Catalog for 2014 - 2015. As a vertically integrated company we develop, manufacture and market highly innovative and fully automated systems for cancer diagnosis, prognosis and therapy selection. Xmatrx® systems redefine complete automation for the molecular pathology laboratory and standardize all the steps from baking through final cover-slipping in three simple steps - Load, Click and View. Compared to any other system on the market, Xmatrx® systems offer clean intense stain(s), automate more assay steps, and enable automation of technologies for the future molecular pathology laboratory. • Xmatrx® ELITE integrates All-in-One and All-at-Once staining of IHC, ISH, special stains and beyond • Xmatrx® Infinity is a high-performance staining platform for life sciences and translational research • Xmatrx® ULTRA is the next-generation system with new features such as touch screen and SMS intelligence • Xmatrx® NANO is a ten-slide automated system specifically designed for FISH • Xmatrx® MINI enables in situ PCR and nucleic acid hybridization with tools for building micro-chamber We also offer a series of i6000TM systems with very high throughput; 200 slides in an 8-hour shift. To maintain our tradition of offering superior solutions for the emerging needs of your laboratory, we offer a broad range of molecular pathology products for IHC, ISH, miRNA, multiplex and special staining of tissues including 300+ primary antibodies, molecular probes, detection systems, and ancillaries. These are offered for standardized, reliable and consistent results to support the needs of molecular pathology laboratories of today, tomorrow and beyond. BioGenex is committed to the core values of innovation, reliability, productivity, quality and superior after sales support and service for complete customer satisfaction. These values are represented by our company’s colors that stand for “energy and innovation” (orange) and “reliability” (blue). I invite you to learn more about our exciting products and future development through this catalog and our new website at www.biogenex.com. Should you have any suggestions for improving our products and services, I encourage you to write me directly at [email protected]. Give us an opportunity and experience the difference. Warm Regards, Krishan Kalra, Ph.D. CEO i [email protected] To become a global “molecular medicine company providing affordable solutions for life science research and “ personalized medicine Dr. Krishan Kalra Innovation Quality Service Reliability Productivity ii www.biogenex.com Table of Contents Overview.....................................................................................iv Multi-Staining General Information..................................................................v Super Sensitive™ Double Stain Polymer Detection System.......144 Additional Information .............................................................v Super Sensitive™ Antibody Cocktails......................................145 Ordering Information.................................................................vi Technical Information...............................................................vi ISH Probes & ISH Detection Systems in situ Hybridization Probes.....................................................150 Automated Systems microRNA Probes......................................................................152 Xmatrx® ELITE...........................................................................02 Hybridization Detection System...............................................158 Xmatrx® ULTRA.........................................................................03 Xmatrx® NANO..........................................................................04 eFISHiency Xmatrx® MINI............................................................................05 eFISHiency................................................................................160 Xmatrx® Infinity.........................................................................06 eFISHiency probes....................................................................161 Xmatrx® FISH (eFISHiency)......................................................07 eFISH pretreatment kits...........................................................163 i6000TM Diagnostics................................................................08 eFISH Processing systems.......................................................164 i6000TM Infinity........................................................................09 i500 PlusTM...............................................................................10 Special Stains Xmatrx® Associated Reagents and Consumables.................11 Special Stains...........................................................................168 i6000TM Associated Reagents and Consumables.................23 i500 PlusTM Associated Consumables....................................30 Ancillary Reagents Buffers and Diluents................................................................176 Tissue Pre-treatment & Antigen Retrieval Blocking Reagents....................................................................177 EZ-DeWaxTM Solution................................................................32 Substrates and Chromogens...................................................178 Antigen Retrieval Method........................................................33 Negative Control Sera/Immunoglobulins...............................179 Antigen Retrieval Accessory Kit..............................................34 Counterstains and Mounting Media.......................................180 EZ-ARTM Elegance Solutions....................................................34 Microscope Slides and Accessories........................................181 EZ-ARTM Solutions....................................................................35 Antigen Retrieval Solutions.....................................................36 Tissue Control Enzymes for Tissue Digestion.................................................38 Positive Control Slides and Barrier Slides..............................184 NordicWare® Microwave Tender Cooker.................................39 Index Primary Antibodies Alphabetical Product Name Index .........................................194 Antibody Look-Up Table.......................................................... 43 Catalog Number Index.............................................................210 Antibody Details.......................................................................51 Antibody Clone Index...............................................................219 Listing by Categories...............................................................228 IHC Detection Systems Super SensitiveTM IHC Detection Systems...........................138 General Terms and Conditions...............................................237 Super SensitiveTM One-Step Polymer-HRP Detection- Systems.................................................................................139 Super SensitiveTM Link-Label IHC Detection Systems.........140 Links and Labels...................................................................142 For latest product offerings visit our website www.biogenex.com or contact our customer support: [email protected] iii [email protected] Overview rd BioGenex celebrated its 33 anniversary serving the Reliability anatomic pathology market. We take great pride in providing BioGenex products give consistent, reproducible and reliable premier service and support while bringing new and results. Our automated systems are highly reliable and technologically advanced products to the market. dependable, giving our customer peace of mind. BioGenex provides a “Total Solution” for slide-based cell Innovation and tissue analysis. Our products include a wide variety BioGenex has a rich history of innovation in the field of of antibodies, highly sensitive detection kits, and probes Immunohistochemistry (IHC) and In situ Hybridization (ISH). for ISH. Our automated systems streamline operations BioGenex has a strong intellectual portfolio, consisting in molecular and cellular pathology laboratories, of several US and foreign-issued patents, in the areas of providing effective tools for the detection and diagnosis of cancer and other diseases. BioGenex continues • DNA labeling and amplification • Antigen retrieval and deparaffinization to innovate as evidenced by the launch of the Xmatrx® • Automation of tissue and cell sample preparation Staining System which provides