Anti-BVES (aa 312-342) polyclonal antibody (DPABH-09233) This product is for research use only and is not intended for diagnostic use. PRODUCT INFORMATION Antigen Description Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells. Plays a role in VAMP3-mediated vesicular transport and recycling of different receptor molecules through its interaction with VAMP3. Plays a role in the regulation of cell shape and movement by modulating the Rho-family GTPase activity through its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner. Also involved in striated muscle regeneration and repair and in the regulation of cell spreading. Immunogen Synthetic peptide within Human BVES aa 312-342 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.Database link: Q8NE79 Isotype IgG Source/Host Rabbit Species Reactivity Human Purification Protein A purified Conjugate Unconjugated Applications IHC-P, WB Format Liquid Size 400 μl Buffer Constituent: 99% PBS Preservative 0.09% Sodium Azide Storage Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. GENE INFORMATION 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved Gene Name BVES blood vessel epicardial substance [ Homo sapiens ] Official Symbol BVES Synonyms BVES; blood vessel epicardial substance; HBVES; POP1; POPDC1; popeye domain containing 1; popeye protein 1; popeye domain-containing protein 1; MGC42413; Entrez Gene ID 11149 Protein Refseq NP_001186492 UniProt ID Q8NE79 Chromosome Location 6q21 Function structural molecule activity; 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved.