Cell News Newsletter of the German Society for Cell Biology full electronic version Volume 44, 2 2017 Report from the DGZ Spring Member Meeting in Leipzig Adding efficiency to your fluorescence imaging. ZEISS Celldiscoverer 7 More Information at DGZ Spring Meeting // INNOVATION MADE BY ZEISS Your automated platform for live cell imaging Imagine the ease of use and automation of a boxed microscope – combined with the image quality and flexibility of a classical research microscope. Imagine this system calibrates itself, detects and focusses your samples and adaptive optics adjust themselves automatically. ZEISS Celldiscoverer 7 is your reliable automated research platform. No matter if you work with 2D or 3D cell culture, tissue sections or small model organisms. With Celldiscoverer 7 you increase the efficiency of your research. You acquire better data in a shorter time. www.zeiss.com/celldiscoverer Adding efficiency CONTENT to your fluorescence imaging. Newsletter of the German Society ZEISS Celldiscoverer 7 for Cell Biology More Information at Preface 4 Executive Board DGZ Spring DGZ Young Scientists Forum 2018 5 Meeting President: Minutes of the DGZ Member Meeting 2017 6 Carien Niessen (Cologne) DGZ Award Winners 2017 Vice President: Oliver Gruss (Bonn) Nikon Young Scientist Award: Evgenij Fiskin: 8 Regulation of host-pathogen interactions by the ubiquitin system Chief Executive Officer (CEO): Thomas M. Magin (Leipzig) Binder Innovation Prize: Sara Wickström: 14 Regulation of epidermal stem cell fate by niche-derived Vice CEO: signals and mechanical forces Karin Schumacher (Heidelberg) Werner Risau Prize: Kerstin Wilhelm: 20 FOXO1 couples metabolic activity and growth statein Advisory Board the vascular endothelium M. Cristina Cardoso (Darmstadt) Thomas Dresselhaus (Regensburg) Future Meetings Reinhard Fässler (Martinsried) Volker Gerke (Muenster) 16th Workshop „Cell Biology of Viral Infections“ 27 Ralph Gräf (Potsdam) // INNOVATION Harald Herrmann (Heidelberg) 21st Joint Meeting of the Signal Transduction Society (STS) 31 Ingrid Hoffmann (Heidelberg) MADE BY ZEISS Heinrich Leonhardt (Martinsried) Meeting Report Zeynep Ökten (Munich) Britta Qualmann (Jena) Meeting report of the DGZ study group ‘Signal Transduction’ 28 Simone Reber (Berlin) and its participation in the 20th anniversary Joint Meeting "Signal Transduction – Receptors, Mediators and Genes" Office: Sabine Reichel-Klingmann Impressum / Members Your automated platform for live cell imaging c/o Deutsches Krebsforschungs- zentrum (DKFZ) Imagine the ease of use and automation of a boxed microscope – combined Im Neuenheimer Feld 280 with the image quality and flexibility of a classical research microscope. 69120 Heidelberg Tel.: 0 62 21/42-34 51 Imagine this system calibrates itself, detects and focusses your samples and Fax: 0 62 21/42-34 52 adaptive optics adjust themselves automatically. ZEISS Celldiscoverer 7 is your E-Mail: [email protected] reliable automated research platform. No matter if you work with 2D or 3D Internet: www.zellbiologie.de cell culture, tissue sections or small model organisms. With Celldiscoverer 7 you increase the efficiency of your research. You acquire better data in a shorter time. Cover Image: Peter Walter giving the Carl Zeiss Lecture 2017 in Leipzig. (Photo: Ralph Gräf) www.zeiss.com/celldiscoverer Cell News 01/2017 3 PREFACE DEAR COLLEAGUES Please look into the present issue of Cell News that highlights the Unfortunately, despite multiple calls to come and discuss the 2017 DGZ prize winners: the Nikon Young Scientist Award winner future of the DGZ and showcasting fantastic science, this member Evgenij Fiskin from Goethe-University Frankfurt, the Binder Inno- meeting with its short format, still did not mobilize the majority of vation Prize winner Sara Wickström from the University of Cologne our member community. The executive board of the DGZ therefore and the Max-Planck-Institute for Biology of Ageing and the Werner decided to go back to our established format of an International Risau Prize prize winner Kerstin Wilhelm from the Max-Planck-In- Meeting as a platform for exchange, to hear cutting-edge cell stitute for Heart and Lung Research in Bad Nauheim. They present biology and to meet our sponsors. The DGZ International Meeting their research on p 8, 14 and 20, respectively. will take place in Leipzig from September 17 to 19, 2018. Moreover, Simone Reber from the Humboldt University, Berlin, will We look back on a scientifically highly successful and inspiring organise a Young Investigator meeting on quantitative Biology DGZ spring meeting that took place on March 1 and 2 in Leipzig. on February 27/28, 2018 targeted at PhD students, postdocs and The former president of the American Society of Cell Biology, Peter early PIs. Please find a preliminary program overview in this Cell Walter (see cover image!), thrilled the audience when giving the news issue. Carl Zeiss Lecture and presenting his ground-breaking work on protein quality control on the first day of our member meeting. Take the chance and convince yourself about the extraordinary The above mentioned prizes awardees were honoured and gave science in the cell biology field when reading this Cell News issue. outstanding presentations. On the second day of the meeting, The DGZ meetings are always worth the trip and we need your the Walther Flemming Award winner, Kikue Tachibana-Konwalski support to make them a success. We are looking forward to seeing joined us and introduced her fascinating research when receiving you at the next DGZ meeting! the award. In addition, young DGZ member PIs, Simone Reber (Berlin), Martin Beck (Heidelberg), Susanne Önel (Marburg) and Carien Niessen Julia Gross (Göttingen) organized 4 fantastic sessions that covered Oliver Gruss a wide range of cell biology and stimulated a lot of discussion. The Thomas M. Magin meeting, as announced, also included a DGZ member forum on Karin Schumacher the future of the DGZ, in which we received very valuable feed- back. The 2017 DGZ Spring meeting was an incredibly stimulating, intense meeting with excellent science and dense communication. DGZ Young Scientists‘ Forum 2018 In February 2018, the German Society for Cell Biology will hold an international meeting organized by and for junior scientists with a special focus on early independence. The upcoming DGZ Young Scientists’ Forum topics will - amongst others - include maintenance of cell identity, synthetic biology, dynamic cytoskeletal systems, emergent core technologies and other relevant and challenging topics (see page 5). The meeting will take place on February, 26th and 27th in Berlin. Save the date for this highly interactive, scientifically stimulating and fun meeting! 4 Cell News 02/2017 DGZ YOUNG SCIENTISTS FORUM 2018 Deutsche Gesellschaft für Zellbiologie Young Scientists’ Forum 26. & 27.02.2018 Berlin Homeostasis and Adapta- tion: How Cells and Com- Dynamic Cytoskeletal Cell Shape in Space and Time partments Change whilst Systems Maintaining their Identity hosted by hosted by Alba Diz-Muñoz & Gaia Pigino hosted by Peter Bieling & Alex Bird Robert Ernst & James Saenz Quantitative Imaging Bottom up Synthetic Biology Science & Society of Development hosted by hosted by hosted by Dora Tang Simone Reber Stephan Preibisch APPLICATION & ABSTRACT DEADLINE: 01.12.2017 SCIENTIFIC ORGANIZER: Simone Reber CONTACT: [email protected] Cell News 01/2017 5 MINUTES OF THE DGZ MEMBER MEETING Protokoll der DGZ-Mitgliederversammlung am 01.03.2017 in Leipzig HS 8, Universität Leipzig Anwesende: 40 MitgliederInnen 1. Confirmation of the minutes of the last year’s Äußerungen der Mitglieder: DGZ member meeting 2016 Einstimmig angenommen • Themenfokussiertes oder breit angelegtes Meeting: überwäl- tigende Mehrheit für breit angelegtes Meeting, Länge 3 volle 2. The president’s annual report Tage (über 4 Tage verteilt) K. Niessen bittet um Zustimmung, keinen ausführlichen • Wenig Parallel-Sitzungen Bericht vorzulegen, weil seit AM 2016 keine einschneidenden • High profile Sprecher sind wichtig Dinge zu berichten sind: keine Einwände • Möglichst viele Mitglieder sollen vortragen (15 min Vorträge) • Ständiges Organisations-Komitee aus 4-5 Mitgliedern zur 3. Financial and auditors report Organisation von Tagungen; ¼ der Mitglieder sollen jährlich O. Gruss stellt den Finanzbericht vor. Keine Fragen. Bitte um ersetzt werden Entlastung des Vorstands (R. Gräf): einstimmig angenommen • Professioneller Tagungsorganisator soll wieder an Bord sein (MCI oder andere) Neubestellung auditors: Ralph Gräf und Julia Gross stehen • Vorschlag: Royal Society for Microscopy (UK) möchte an ab Kassenjahr 2018 zur Verfügung. Tagung teilnehmen und 1-2 sessions gestalten; einhellige Zustimmung; R. Faix kümmert sich um Kontakte und konkrete 4. C. Niessen stellt folgende Punkte nach kurzer Erläuterung Planung, sobald Ort und Zeitpunkt des 2018 International zur Diskussion: Meetings festliegen a. Our mission • GBM möchte Kooperation mit DGZ stark intensivieren, die b. What do members expect of the DGZ GBM hat momentan ~5.500 Mitglieder. Bei GBM gibt es lokale c. Future Goals of DGZ Junior groups, die sehr erfolgreich sind und für die Reisesti- d. Cooperation with GBM and other related societies pendien etc. verfügbar sind. Bringen viele Jungmitglieder zu e. Means to achieve goals Tagungen. Außerdem gibt es study sections f. Problem: only ~10 % of members attend meeting, unlike in • Optionen für Kooperation: punktuelle Zusammenarbeit, other societies Gründung einer neuen Dachgesellschaft für Life Sciences; ein-