PLATINUM SPONSORS SCHEDULE SESSION TWO (continued) COPa Library: A Protein Knowledgebase for BioPharmaceutical Technology Center Institute Cardiovascular Biology and Medicine Human Proteomics Program, THURSDAY, AUGUST 4, 2011 -Peipei Ping, Ph.D. University of Wisconsin-Madison 2 –4pm OPEN HOUSES at the University of Wisconsin The Cell-Environment Interface – Applications to Michael Best & Friedrich LLP Biotechnology Center Core Facility, Human Heart Disease and Biomarkers -Jennifer Van Eyk, Ph.D. Promega Corporation Proteomics Program Core Facility and Chemistry Top-Down Disease Proteomics of Myofi laments for Instrument Center Mass Spectrometry Facility Thermo Scientifi c Understanding Heart Failure -Ying Ge, Ph.D. 4:30–6:30pm RECEPTION: Pyle Center (Alumni Lounge) Name DAY ONE: CONCLUDING REMARKS GOLD SPONSORS badges and Symposium packets will be available at the Registration Table here. 5-6pm RECEPTION / POSTER SESSION / EXHIBITS AB SCIEX Bruker Daltonics Eksigent FRIDAY, AUGUST 5, 2011 SATURDAY, AUGUST 6, 2011 Waters Corporation 8–9am REGISTRATION / CONTINENTAL BREAKFAST / EXHIBITS 8–9am REGISTRATION / CONTINENTAL BREAKFAST /EXHIBITS SILVER SPONSORS 9–9:15am WELCOME: Richard Moss, Ph.D., Honorary 9–11am SESSION THREE: Proteomics Applications in Advion BioSciences, Inc. Symposium Chair Neurodegenerative Diseases Session Chair: Martha Vestling, Ph.D. Agilent Technologies 9:15-10am KEYNOTE ADDRESS: Advances in LC-MS Based Cambridge Isotope Laboratories, Inc. Proteomics -Richard Smith, Ph.D. Mass Spectrometric Analysis of Neuropeptides from Single Ascaris Neurons -Antony Stretton, Ph.D. City of Fitchburg Proteomic Technologies Towards the Membrane FOTODYNE Incorporated 10-11am SESSION ONE: Proteomics Technologies Session Chair: Michael Sussman, Ph.D. Proteome: Applications in Neuroscience Master of Science in Biotechnology Program, -Christine Wu, Ph.D. University of Wisconsin-Madison Proteomic Technologies for the Genome Age -Lloyd Smith, Ph.D. Regulation of SMN and Identifi cation of its New England Peptide Downstream Targets -Judith Steen, Ph.D Precursor Acquisition Independent from Ion Count: New Objective Extending Proteomic Dynamic Range without Mass Spectrometry-based Tools for Biomarker Discovery in Neurological Disorders -Lingjun Li, Ph.D. Pressure BioSciences, Inc. Prior Fractionation -David Goodlett, Ph.D. 11-11:15am BREAK 11 –11:15am BREAK 11:15–12:15pm SESSION ONE (continued) 11:15-12:15pm SESSION FOUR: Proteomics Applications in Cancer SYMPOSIUM How High Mass Accuracy Measurements Session Chair: William F. Dove, Ph.D. Will Transform Targeted Proteomics Application of Proteomics to Cancer and ORGANIZING COMMITTEE -Joshua Coon, Ph.D. Personalized Medicine -Sam Hanash, Ph.D. Developing Integrated Proteomic Approaches Comprehensive Glycomics for Biomarker Discovery YING GE, PH.D. for Comprehensive Profi ling of Protein Complexes and Nutrition -Carlito Lebrilla, Ph.D. Director of Mass Spectrometry -Lan Huang, Ph.D. Human Proteomics Program 12:15-1:45pm LUNCH / POSTER SESSION / EXHIBITS School of Medicine and Public Health 12:15-1:45pm LUNCH / POSTER SESSION / EXHIBITS University of Wisconsin-Madison 1:45-4:15pm SESSION FOUR (continued) LINGJUN LI, PH.D. 1:45-2:45pm SESSION ONE (continued) Session Chair: John Denu, Ph.D. Can Mass Spectrometry and Protein Footprinting Associate Professor Unraveling Novel Molecular Mechanisms of Action School of Pharmacy and Dept of Chemistry Play a Role in Structural Biology? -Michael Gross, Ph.D. of Thiopurine Drugs -Yinsheng Wang, Ph.D. University of Wisconsin-Madison A Top Down Approach to the Human Proteome Electron Irradiation of Cat- and Anions: A Potential -Neil Kelleher, Ph.D. Analytical Tool in both Proteomics and Glycomics MARTHA VESTLING, PH.D. -Kristina Hakansson, Ph.D. Director, Mass Spectrometry Facility Discovery and Characterization of Novel Lysine Department of Chemistry 2:45-3pm BREAK Modifi cations -Yingming Zhao, Ph.D. University of Wisconsin-Madison From Innovative Technologies to Model Organisms: 3-5pm SESSION TWO: Proteomics Applications in The Search for Biomarkers for the Detection of Early AMY PREVOST, M.S. Cardiovascular Diseases Stage Epithelial Ovarian Cancer Director of Scientifi c Courses Session Chair: Marion Greaser, Ph.D. –David Muddiman, Ph.D. BioPharmaceutical Technology Center Institute Electron-Based Dissociation Methods for Glycans, DISCUSSION & CONCLUDING REMARKS Glycopeptides and Glycoproteins KARIN BORGH, PH.D. -Catherine Costello, Ph.D. Executive Director 4:15-5pm RECEPTION (desserts) BioPharmaceutical Technology Center Institute HONORARY SYMPOSIUM CHAIR: SPEAKERS: Richard Moss, Ph.D. Joshua Coon, Ph.D. Neil Kelleher, Ph.D. Antony O. W. Stretton, Ph.D. University of Wisconsin-Madison University of Wisconsin-Madison Northwestern University University of Wisconsin-Madison Professor, Department of Cell and Associate Professor Professor of Molecular Biosciences Professor, Zoology Department Regenerative Biology Departments of Chemistry and Bimolecular Chemistry Department of Molecular Biosciences and Neuroscience Training Program Senior Associate Dean for Basic Research Weinberg College of Arts and Sciences Biotechnology and Graduate Studies Catherine E. Costello, Ph.D. Director, Proteomics Center of Excellence Jennifer Van Eyk, Ph.D. Boston University School of Medicine Johns Hopkins School of Medicine Executive Director, Master of Science in Biotechnology Professor, Departments of Biochemistry and Biophysics Director and Center Investigator Director, UW Cardiovascular Research Center Carlito B. Lebrilla, Ph.D. The Johns Hopkins NHLBI Proteomics Center School of Medicine and Public Health Director, Mass Spectrometry Resource University of California, Davis Director, Cardiovascular Proteomics Center Professor, Department of Chemistry Director, Bayview Proteomics Center KEYNOTE SPEAKER: Professor of Medicine, Division of Cardiology Richard D. Smith, Ph.D. Ying Ge, Ph.D. Lingjun Li, Ph.D. Biological Chemistry and Biomedical Engineering Pacific Northwest National Laboratory University of Wisconsin-Madison University of Wisconsin-Madison Battelle Fellow and Chief Scientist Director of Mass Spectrometry, Human Proteomics Program Associate Professor Christine C. Wu, Ph.D. School of Medicine and Public Health School of Pharmacy and Department of Chemistry University of Pittsburgh School of Medicine Environmental Molecular Sciences Laboratory and Biological Sciences Division Associate Professor David R. Goodlett, Ph.D. David C. Muddiman, Ph.D. Department of Cell Biology and Physiology SESSION CHAIRS: University of Washington North Carolina State University Professor, Medicinal Chemistry Professor, Mass Spectrometry Yinsheng Wang, Ph.D. Michael R. Sussman, Ph.D. [Session One] Department of Chemistry University of Wisconsin-Madison University of California at Riverside Michael L. Gross, Ph.D. Professor, Department of Biochemistry Professor in Chemistry Washington University Peipei Ping, Ph.D., FISHR, FAHA Director Environmental Toxicology Graduate Program Director, UW Biotechnology Center Professor, Department of Chemistry University of California, Los Angeles Professor of Immunology and Internal Medicine Professor and Director Yingming Zhao, Ph.D. Marion Greaser, Ph.D. [Session Two] NHLBI Proteomics Center at UCLA University of Chicago University of Wisconsin-Madison Director and Principal Investigator Mass Spectrometry Resource NHLBI PPG on Myocardial Ischemic Injury Associate Professor, The Ben May Professor, Department of Animal Sciences Department for Cancer Research School of Medicine Director of the Muscle Biology Laboratory Kristina Hakansson, Ph.D. University of Michigan Lloyd M. Smith, Ph.D. Martha M. Vestling, Ph.D. [Session Three] Associate Professor of Chemistry University of Wisconsin-Madison University of Wisconsin-Madison Professor, Department of Chemistry Director of the Mass Spectrometry Facility Sam Hanash, M.D., Ph.D. OVERVIEW Department of Chemistry Fred Hutchinson Cancer Research Center Judith A. J. Steen, Ph.D. Program Head and Full Member, Molecular Diagnostics Harvard Medical School The Human Proteomics Program at Assistant Professor of Neurology William F. Dove, Ph.D. [Session Four] Public Health Sciences the University of Wisconsin-Madison and University of Wisconsin-Madison Associate in Neurology Lan Huang, Ph.D. the BioPharmaceutical Technology Center George Streisinger Professor of Experimental Biology F.M. Kirby Neurobiology Center University of California, Irvine Children’s Hospital Boston Institute are pleased to offer this excellent Professor of Oncology and Medical Genetics Associate Professor, Developmental & Cell Biology program. Nationally recognized researchers in modern mass McArdle Laboratory for Cancer Research School of Biological Sciences spectrometry/proteomics will present their current work, with an School of Medicine and Public Health Associate Professor, Physiology & Biophysics emphasis on how these technologies will impact human health. School of Medicine John M. Denu, Ph.D. [Session Four] University of Wisconsin-Madison Speakers will address a range of proteomics applications in basic and clinical Epigenetics Theme Leader biomedical research, instrumentation/technique development and potential Wisconsin Institute for Discovery applications in clinical practice. All talks will be presented in a plenary format. Attendees Professor, Biomolecular Chemistry School of Medicine and Public Health can expect to hear about cutting-edge proteomics technology developments and proteomics applications in cardiovascular diseases, cancer and neurodegenerative diseases..