Printer-friendly Page 1 of 3 Published on NYU Langone Medical Center (http://www.med.nyu.edu_) Home > Printer-friendly > Printer-friendly Printer-friendly Biosketeh / Results / Orrin Devinsky, M.D. Professor; Dir Comprehensive Epilepsy Ctr Departments of Neurology (Administration) Neurosurgery (Neurosurgery) i21 and Psychiatry Clinical [6] Addresses 223 EAST 34TH STREET, GROUND FLOOR NEWYORK, NY 10016 Hours: Mon. 9 -4; Wed. 9 - 4 Handicap Access: yes Phone: 646-558-0803 Fax: 646-385-7164 Addtional Clinical Addresses [41 Web: f.a.c.e.s. Comprehensive Epilepsy Center ~; Education Details ~: Research ! Publications;! http://www.med.nyu.edu/printibiosketch!od4 511012011 printer-friendly Page 2 of 3 Back to Results Medical Specialties Pediatric Neurology/Epilepsy, Neurology Medical Expertise Seizure Disorders (Epilepsy) Clinical Responsibilities Dr. Devinsky is Professor of Neurology, Neurosurgery, and Psychiatry at NYU School of Medicine. He directs the NYU Comprehensive Epilepsy Center and the Saint Barnabas Institute of Neurology and Neurosurgery (INN). He received his B.S. and M.S. from Yale University, M.D. from Harvard Medical School and interned at Boston’s Beth Israel Hospital. He completed neurology training at the New York HospitaI-Cornell Medical Center and his epilepsy fellowship at the NIH. Dr. Devinsky’s epilepsy research interests include quality-of-life, cognitive and behavioral issues in epilepsy, surgical therapy, and new medications, He has published widely in epilepsy and behavioral neurology, with more than 250 articles and chapters and more than 20 books and monographs. He has chaired several committees of the American Epilepsy Society and has served as a Board member. He is active in the American Academy of Neurology and the Epilepsy Foundation. He is the Co-Editor of Reviews in Neurological Diseases, Epilepsy and Behavior, and Epilepsy.corn, and serves as a reviewer for more than 30 journals. Director, Institute of Neurology Saint Barnabas Medical Center, Livingston, NJ Insurance AETNA HMO, AETNA INDEMNITY, AETNA MEDICARE, AETNA POS, AETNA PPO, Beech St PPO, Cigna HMO/POS, Cigna PPO, EBCBS CHLD HLTH, EBCBS EPO, EBCBS HLTHY NY, EBCBS HMO, EBCBS INDEMNITY, EBCBS MEDIBLUE, EBCBS POS, EBCBS PPO, HIP ACCESS I, HIP ACCESS II, HIP CHLD HLTH, HIP EPO/PPO, HIP HMO, HIP MEDICARE, HIP POS, MULTIPLAN/PHCS PPO, OXFORD FREEDOM, http://www.med.nyu.edu/printJbiosketch/od4 5/10/2011 Primer-friendly Page 3 of 3 Source URL: http:llwww.med.nyu.edulbiosketchlod4 Links: [1] http:llwww.med.nyu.edulNeurol [2] http:llwww.med.nyu.edulneurosurgeryl [3] http:llwww.med.nyu.edulPsychl [4] http:llwww.med.nyu.eduljavascript%3AtoggleAddress%28%29%3B [5] http:llwww.med.nyu.edulhttp [6] http:llwww.med.nyu.edulfind-doctodupdate-your-clinical-profile [7] http:~~www~med~nyu~edu~javascript%3Achange-tab%28%27bi~sketch%27%2c%2~%27inf~%27%29%3B [8] http:~~www~med~nyu~edu~javascript%3A~hange-tab%28%27bi~sketch%27%2c%2~%27educati~n%27%29% 3B [9] http:~~www~med~nyu~edu~javascript%3Achange-tab%28%27bi~sketch%27%2c%2~%27research%27%29%3B [1 O] http:~~www~med.nyu~edu~javascript%3Achange-tab%28%27bi~sket~h%27%2c%2~%27pub~icati~ns%27% 29%3B [11] http://www.med.nyu.edu/od4 [12] http:llhsl.med.nyu.edulfaculty-bibliography-search#about http ://www.med.nyu.edu/printPoio sketch/od4 5/10/2011 Orrin Devinsky I NYU Langone Medical Center Page 1 of 1 Publications Clinical lnfo ii~ Research ii Back to Results Board Certification Education 1987 -- Neurology 1982-1983 -- Beth Israel Hospital, Internship 1983-1986 -- New York Presbyterian - Weill Comell Medical Center (Neurology), Residency Training 1986-1988 -- National Institute of Health, Clinical Fellowships http ://www.med.nyu.edu!bio sketch/od4 5/10/2011 .Orrin Devinsky I NYU Langone Medical Center Page 1 of 1 Research Summary The Comprehensive Epilepsy Center, directed by Orrin Devinsky, M.D., offers multidisciplinary evaluation, medical treatment and surgical intervention for epilepsies by a team of epileptologists, neuropsychologists, neurosurgeons, psychiatrists, and other specially trained support personnel. The major goal of the Center is to provide comprehensive care to people with epilepsy. Routine and advanced diagnostic studies, 10 clinical pharmacologic trials, and a variety of therapeutic interventions are carried out to better understand the disorder and improve treatment. Dr. Devinsky and his co-investigatore are presently conducting studies of several investigational antiepileptic medications such as topiremate, tiagabine, lamotrigine, vigabatrin, oxcarbazepine, and remacemide, as well as vagal nerve stimulator implantation. The Comprehensive Epilepsy Center offers 16 inpatient video- EEG-monitored beds in a specialized Epilepsy Monitoring Unit. Each bed has the capacity for 64 channels of EEG data with on- line computer analysis for 24-hour seizure and spike detection. Preoperative neurepsychological assessment, invasive monitoring including depth and subdural electrode studies, intraoperetive electrecorticography and functional localization of language, motor and sensory areas permits precise surgical approaches to remove epileptic tissue while sparing necessary brain areas. Research Interests Epilepsy and Seizure Disorders Research Keywords epilepsy, seizure disorders http://www.med.nyu.edu!biosketch/od4 5/10/2011 Primer,friendly Page 1 of 3 Published on NYU Langone Medical Center (http://www.med.nyu.edu) Home ¯ Printer-friendly ¯ Printer-friendly Printer-friendly Biosketch / Results / Orrin Devinsky, M.D. Professor; Dir Comprehensive Epilepsy Ctr Departments of Neurology (Administration) Neurosurgery (Neurosurgery) i2] and Psychiatry Clinical Addresses 223 EAST 34TH STREET, GROUND FLOOR NEWYORK, NY 10016 Hours: Mon. 9 -4; Wed. 9 - 4 Handicap Access: yes Phone: 646-558-0803 Fax: 646-385-7164 Addtional Clinical Addresses [4] Web: f.a.c.e.s. 1~]; Comprehensive Epilepsy Center [~]; Clinical Info Education Details Research ] http://www.med.nyu.edu/print/biosketch!od4/publications 5/10/2011 Primer-friendly Page 2 of 3 << Back to Results t11] All data from NYU School of Medicine Ehrman Medical Library Faculty Bibliography m Data may be incomplete Contact: http://hsl.med.nyu.edu/faculty-bibliography-search#about [12] Imaging Inflammation in a Patient with Epilepsy Due to Focal Cortical Dysplasia Butler 7," Ichise M; Teich AF; Gerard E; Osborne J; French J; Devinsky O; Kuzniecky R; Gilliam F; Pervez F; Provenzano F; Goldsmith S; Vallabhajosula S; Stern E; Silbersweig D 2011 Jan 11. doi: 10.1111/j.1552-6569.2010.00572.x ## 10.1111/j.1552- 6569.2010.00572.x [doi], Journal of neuroimaging BACKGROUND AND PURPOSE: Evidence from animal models and examination of human epilepsy surgery specimens indicates that inflammation plays an important role in epilepsy. Positron emission tomography (PET) using [C11]PK11195, a marker of activated microgiia, provides a means to visualize neuroinflammation in vivo in humans. We hypothesize that in patients with active epilepsy, [Cl 1]PK11195 PET (PK-PET) may be able to identify areas of focally increased inflammation corresponding to the seizure onset zone. METHODS: A young woman with intractable epilepsy underwent PK-PET as part of an approved research study. PK- PET results were compared with results from other clinical studies. RESULTS: PK- PET revealed an area of focally increased radiotracer uptake in the right frontal lobe corresponding to this patient’s seizure focus as identified by ictal and interictal 18F- fluorodeoxyglucose (FDG)-PET and EEG. Routine brain magnetic resonance imaging (MRI) was initially considered normal, though high-resolution studies showed possible subtle dysplasia of the right frontal lobe. The patient underwent a right frontal lobe resection, and pathological evaluation showed focal cortical dysplasia with activated microglia. CONCLUSIONS: PK-PET can identify neuroinflammation associated with subtle focal cortical dysplasia, and may therefore have a clinical role in guiding epilepsy surgery for patients with difficult-to-localize seizure foci. J Neuroimaging 2011;XX:1-3 mid: J0203407, year: 2011, vol:, page: ?, stat: Journal Article, Bilateral invasive electroencephalography in patients with tuberous sclerosis complex: a path to surgery? Clinical article Carlson, Chad; Teutonico, Federica; Elliott, Robert E.; Moshel, Yaron A.; LaJoie, Josiane; Miles, Daniel; Devinsky, Orrin; Weiner, Howard L. 2011 APR;7(4):421-430, Journal of Neurosurgery: Pediatrics Object. Many children with epilepsy and tuberous sclerosis complex (TSC) have multiple tubers on MR imaging and poorly Iocalized/lateralized video electroencephalography (EEG) findings. Given the long-term risks associated with frequent seizures and multiple antiepileptic drugs, along with improved success in identifying focal epileptogenic zones in patients with multifocal lesions, the authors used bilateral intracranial EEG to lateralize the epileptogenic zone in patients with nonlateralizable noninvasive preoperative evaluations. Methods. A retrospective analysis from January 1, 1998, to June 30,2008, identified 62 children with TSC who were presented at a surgical conference. Of the 52 patients undergoing diagnostic or http ://www.med.nyu.edu/print/biosketch/od4/publications 5/10/2011 Printer-friendly Page 3 of 3 Source URL: http:llwww.med.nyu.edulbiosketchlod4/publications Links: [1] http:llwww.med.nyu.edulNeurol [2] http:llwww.med.nyu.edulneurosurgeryl [3] http:llwww.med.nyu.edulPsychl [4] http:llwww.med.nyu.eduljavascript%3AtoggleAddress%28%29%3B [5] http:llwww.med.nyu.edulhttp [6]