Leader in Biomolecular Solutions for Life Science Recombinant Human CLPS/Colipase Protein Catalog No.: RP00125 Recombinant Sequence Information Background Species Gene ID Swiss Prot The protein is a cofactor needed by pancreatic lipase for efficient dietary lipid Human 1208 P04118 hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall Tags hydrophobic binding site. The gene product allows lipase to anchor noncovalently C-6×His to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, Synonyms suggesting regulation of expression by tissue-specific elements. Three transcript variants encoding different isoforms have been found for this gene. Basic Information Product Information Description Recombinant Human CLPS/Colipase Protein is produced by HEK293 expression Source Purification system. The target protein is expressed with sequence (Met1-Gln112) of human HEK293 cells > 90% by SDS- CLPS/Colipase (Accession #NP_001823.1) fused with a 6×His tag at the C-terminus. PAGE. Bio-Activity Endotoxin < 0.1 EU/μg of the protein by LAL Storage method. Store the lyophilized protein at -20°C to -80 °C for long term. After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C Formulation for up to 1 week. Lyophilized from a 0.22 μm filtered Avoid repeated freeze/thaw cycles. solution of PBS, pH 7.4.Contact us for customized product form or formulation. Reconstitution Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Contact www.abclonal.com Validation Data Recombinant Human CLPS/Colipase Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 13 kDa. Antibody | Protein | ELISA Kits | Enzyme | NGS | Service For research use only. Not for therapeutic or diagnostic purposes. Please visit http://abclonal.com for a complete listing of recommended products..